Description
This kit contains recombinant mouse IL-2, IL-4, IL-21, and BAFF for the in vitro polarization of mouse B cells.
IL-2 is typically added as an enhancing component to existing polarization systems. Its most important applications include synergizing with IL-4 to enhance IgG1/IgE class switching, and with TGF-β to enhance IgA class switching. In the early stages of the B cell response, it promotes clonal expansion and prepares cells for class switching; in later stages, it may influence the fate decision between plasma cells and memory B cells.
IL-4 is the core instructive factor for IgG1 and IgE class switching. In T cell-dependent responses, IL-4 is the most critical cytokine for inducing B cells to switch from expressing IgM/IgD to expressing IgG1 and IgE. Meanwhile, it is a potent B cell co-stimulatory proliferation factor, acting synergistically with BCR or CD40 signaling.
IL-21 induces B cell differentiation into plasma cells and antibody secretion.
BAFF promotes B cell survival and maturation.
Product Information
|
Product Information. |
Catalog Number |
Size |
|
Mouse B lymphocyte Polarization Cytokine Set |
92655ES10 |
10 μg |
|
92655ES50 |
50 μg |
|
|
92655ES60 |
100 μg |
Components
|
Component Cat No. |
Component Name |
92655ES10 |
92655ES50 |
92655ES60 |
Quantity |
|
92655ES-A |
Mouse IL-2 Protein |
10 μg |
50 μg |
100 μg |
1 |
|
92655ES-B |
Mouse IL-4 Protein |
10 μg |
50 μg |
100 μg |
1 |
|
92655ES-C |
Mouse IL-21 Protein |
10 μg |
50 μg |
100 μg |
1 |
|
92655ES-D |
Mouse BAFF Protein |
10 μg |
50 μg |
100 μg |
1 |
Product Includes
|
Component Cat No. |
Product Name |
Source |
Appearance |
|
90239ES |
Mouse IL-2 Protein |
HEK293 |
Liquid |
|
90241ES |
Mouse IL-4 Protein |
HEK293 |
Liquid |
|
90233ES |
Mouse IL-21 Protein |
HEK293 |
Liquid |
|
90641ES |
Mouse BAFF Protein |
HEK293 |
Lyophilized powder |
Reconstitution Method
|
Component Name |
Reconstitution Method |
|
Recombinant Mouse BAFF Protein |
Before opening, centrifuge to bring the contents to the bottom. Reconstitute with ultrapure water to a concentration of 0.1-1.0 mg/mL. Further dilution can be performed based on subsequent experiments. |
Performance Parameters
|
Species |
Mouse |
|
Tag |
No Tag |
|
Expression System |
HEK293 |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
< 0.01 EU per µg by the LAL method. |
|
Formulation |
PBS buffer. |
|
Appearance |
Liquid |
Storage
Store at -85 ~ -65°C. Valid for 1 year from the date of receipt.
After reconstitution, store at -85 ~ -65°C under sterile conditions for 3 months.
Product Features
High activity, high purity, high stability, low endotoxin.
Documents
Manual
Paiement et sécurité
Vos informations de paiement sont traitées en toute sécurité. Nous ne stockons pas les détails de la carte de crédit ni accès aux informations de votre carte de crédit.
Vous pouvez aussi aimer
Enquête
FAQ
Le produit est destiné à des fins de recherche uniquement et n'est pas destiné à un usage thérapeutique ou diagnostique chez l'homme ou l'animal. Les produits et le contenu sont protégés par des brevets, des marques déposées et des droits d'auteur appartenant à Yeasen Biotechnology. Les symboles de marque indiquent le pays d'origine, pas nécessairement l'enregistrement dans toutes les régions.
Certaines applications peuvent nécessiter des droits de propriété intellectuelle tiers supplémentaires.
Yeasen se consacre à la science éthique, estimant que nos recherches doivent répondre à des questions cruciales tout en garantissant la sécurité et les normes éthiques.