Descrição
CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152 (Cluster of Differentiation 152 is), a protein receptor that downregulates immune responses. As a member of the immunoglobulin superfamily, CTLA-4 is expressed on the surface of helper T cells and delivers an inhibitory signal to regulate T cell activity . Structurally, the protein comprises an extracellular V domain, a transmembrane domain, and a cytoplasmic tail.
Specifications
|
Cat.No. |
96526ES25 / 96526ES60 / 96526ES76 |
|
Size |
25 μg / 100 μg / 500 μg |
Components
|
Name |
96526ES25 |
96526ES60 |
96526ES76 |
|
Recombinant Human BDCA2/DLEC4C Protein,hFc Tag |
25 μg |
100 μg |
500 μg |
Performance parameters
|
Synonyms |
Celiac Disease 3,CD152,CTLA4,CTLA-4 |
|
Species |
Mouse |
|
Expression Sequence: |
Glu36-Asp161 with His & Avi Tag at C-Terminus |
|
Accession |
P09793 |
|
Tag |
C-His-Avi Tag |
|
Expression System |
HEK293 |
|
Molecular Weight |
25-30 kDa (Reducing) |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
< 1.0 EU per μg by the LAL method. |
|
Formulation |
PBS, PH7.4, 5% trehalose |
|
Appearance |
Lyophilized Powder |
|
Reconstitution |
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
Storage
Store at -25°C to -15°C for 1 year upon receipt; after reconstitution under aseptic conditions, the product is stable for 7 days at 2°C to 8°C or for 3 months at -85°C to -65°C.
Product Features
High Activity & Purity, Low Endotoxin, High Lot-to-Lot Consistency.
Application Example
ELISA Data: Immobilized B7-1/CD80 Fc Chimera Protein,Mouse at 5.0 μg/mL (100 μL/well) can bind Biotinylated CTLA-4/CD152 His&Avi Tag Protein,Mouse with EC50 of 6.38-9.26 ng/mL.
Notes
1. This product is for research use only.
2. Please operate with lab coats and disposable gloves, for your safety.
Documents:
Manual
Pagamento e segurança
Suas informações de pagamento são processadas com segurança. Não armazenamos detalhes do cartão de crédito nem temos acesso às informações do seu cartão de crédito.
Você também pode gostar
Investigação
Perguntas frequentes
O produto é apenas para fins de pesquisa e não se destina ao uso terapêutico ou diagnóstico em humanos ou animais. Os produtos e o conteúdo são protegidos por patentes, marcas registradas e direitos autorais de propriedade da
Certos aplicativos podem exigir direitos adicionais de propriedade intelectual de terceiros.