Descrição
PDGFRA is a cell surface receptor protein that binds to Platelet-derived growth factor (PDGF). This activation plays a crucial role in the regulation of cell growth, proliferation, and differentiation. Abnormal expression of PDGFRA can lead to various diseases like cancer and fibrosis.
Product Properties
|
Synonyms |
PDGFRA；CD140A；PDGFR2；RHEPDGFRA；MGC74795 |
|
Uniprot No. |
P16234 |
|
Source |
Recombinant Human PDGFA Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Gln24-Ala528. |
|
Molecular Weight |
The protein has a predicted MW of 57.63 kDa. And it migrates as 72-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
<0.1 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
|
Reconstitution |
Centrifuge tubes before opening. Dissolve lyophilized protein with sterile PBS to ensure the concentration is greater than 100 ug/mL. |
Storage
The product should be stored at -25~-15℃ for 1 year from date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Note
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.
Product Data
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Investigação
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