Descrição
IInterleukin-9 (IL-9) is primarily expressed by activated T cells. IL-9 exerts its biological effects by binding to its specific receptor, IL-9Rα. It promotes Th2-type immune responses and is involved in the pathogenesis of allergic diseases, such as asthma and atopic dermatitis. Furthermore, IL-9 supports the growth of helper T cells in an IL-2 and IL-4-independent manner, and promotes the proliferation of mast cells, erythroid progenitor cells, and other cell types.
Components
|
Name |
90372ES10 |
90372ES50 |
90372ES80 |
|
Recombinant Human IL-9 GMP Protein |
10 μg |
50 μg |
1 mg |
Performance parameters
|
Synonyms |
Interleukin-9, IL-9, Cytokine P40 |
|
Source |
Human IL-9 Protein is expressed from CHO Cells. |
|
Sequence |
Gln 19 - Ile 144 |
|
Molecular Weight |
The protein has a calculated MW of 14.1 kDa. The protein migrates as 40 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
|
Accession |
P15248 |
|
Biological Activity |
The ED50 as determined by the dose-dependent stimulation of the proliferation of human M07e cells is ≤ 2.0 ng/ml. |
|
Purity |
＞95% as determined by SDS-PAGE. |
|
Endotoxin |
＜0.01 EU/μg protein as determined by LAL method. |
|
Sterility |
Negative. |
|
Mycoplasma |
Negative. |
|
Vitro Virus |
Negative. |
|
Host Cell Protein |
Less than 0.5 ng/μg when tested by ELISA. |
|
Host Cell DNA |
Less than 20 ng/mg when tested by qPCR. |
|
Formulation |
Lyophilized from 0.22μm filtered solution in PBS, pH7.4 with trehalose as protectant. |
|
Physical Appearance |
Lyophilized Powder |
Storage
This product should be stored at -25 ~ -15°C for 2 years. After reconstitution, store at -85 to -65°C. Valid for 3 months.
Figure
1. SDS- PAGE
Figure 1. Human IL-9 GMP Protein on SDS-PAGE under reduced condition. The purity is greater than 95%.
2.Cell Based Assay
Figure 2. The ED50 as determined by a cell proliferation assay using human M07e cells is less than 2.0 ng/mL.
Documents:
Safety Data Sheet
Manuals
Pagamento e segurança
Suas informações de pagamento são processadas com segurança. Não armazenamos detalhes do cartão de crédito nem temos acesso às informações do seu cartão de crédito.
Você também pode gostar
Investigação
Perguntas frequentes
O produto é apenas para fins de pesquisa e não se destina ao uso terapêutico ou diagnóstico em humanos ou animais. Os produtos e o conteúdo são protegidos por patentes, marcas registradas e direitos autorais de propriedade da
Certos aplicativos podem exigir direitos adicionais de propriedade intelectual de terceiros.