Frequently Bought Together
PD-L1 is one of the ligands for PD-1 and plays a critical role in the regulation of T cell immunity. The PD-L1 protein belong to the B7 family of immune regulatory molecules. PD-L1 provides a molecular stop signal to the adaptive immune system helping to distinguish between self and foreign antigens. PD-L1 also plays a role in the development of immune tolerance by promoting T cell anergy and enhancing regulatory T cell development.
Specifications
|
Synonyms |
PD-L1,CD274,B7-H1,PDCD1L1,PDCD1LG1,PDL1 |
|
Uniprot No. |
Q9NZQ7 |
|
Source |
Recombinant Human PDL1 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Phe 19- Thr 239. |
|
Molecular Weight |
The protein has a predicted MW of 26 kDa. And it migrates as an approximately 33 kDa under reducing condition in SDS-PAGE due to glycosylation. |
|
Purity |
> 95% as determined by SDS-PAGE |
|
Endotoxin |
<1 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
|
Reconstitution |
Centrifuge tubes before opening. The concentration of protein solution used for lyophilization is generally 1mg/mL. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 μg/mL. |
Storage
The product should be stored at -25~-15℃ for 1 year from date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Note
1.Please operate with lab coats and disposable gloves for your safety.
2.This product is for research use only.
Product Data
SDS-PAGE
Bioactivity -SPR Data
Storage
FAQ
Citations
Documents
Applications
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FAQ
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