Recombinant Human IL-9 GMP Protein _ 90372ES

YeasenSKU: 90372ES10

Size: 10 μg
Fiyat:
Satış fiyatı$265.00

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Stoklamak:
Stokta var

Tanım

IInterleukin-9 (IL-9) is primarily expressed by activated T cells. IL-9 exerts its biological effects by binding to its specific receptor, IL-9Rα. It promotes Th2-type immune responses and is involved in the pathogenesis of allergic diseases, such as asthma and atopic dermatitis. Furthermore, IL-9 supports the growth of helper T cells in an IL-2 and IL-4-independent manner, and promotes the proliferation of mast cells, erythroid progenitor cells, and other cell types.

Components

Name

90372ES10

90372ES50

90372ES80

Recombinant Human IL-9 GMP Protein

10 μg

50 μg

1 mg

Performance parameters

Synonyms

Interleukin-9, IL-9, Cytokine P40

Source

Human IL-9 Protein is expressed from CHO Cells.

Sequence

Gln 19 - Ile 144

Molecular Weight

The protein has a calculated MW of 14.1 kDa. The protein migrates as 40 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession

P15248

Biological Activity

The ED50 as determined by the dose-dependent stimulation of the proliferation of human M07e cells is ≤ 2.0 ng/ml.

Purity

95% as determined by SDS-PAGE.

Endotoxin

0.01 EU/μg protein as determined by LAL method.

Sterility

Negative.

Mycoplasma

Negative.

Vitro Virus

Negative.

Host Cell Protein

Less than 0.5 ng/μg when tested by ELISA.

Host Cell DNA

Less than 20 ng/mg when tested by qPCR.

Formulation

Lyophilized from 0.22μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Physical Appearance

Lyophilized Powder

Storage

This product should be stored at -25 ~ -15°C for 2 years. After reconstitution, store at -85 to -65°C. Valid for 3 months.

Figure

1. SDS- PAGE

Figure 1. Human IL-9 GMP Protein on SDS-PAGE under reduced condition. The purity is greater than 95%.

Figure 1. Human IL-9 GMP Protein on SDS-PAGE under reduced condition. The purity is greater than 95%.

2.Cell Based Assay

Figure 2. The ED50 as determined by a cell proliferation assay using human M07e cells is less than 2.0 ng/mL.

 Figure 2. The ED50 as determined by a cell proliferation assay using human M07e cells is less than 2.0 ng/mL.

Documents:

Safety Data Sheet

90372_MSDS_HB260716

Manuals

90372_Manual_HB20260716

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