C-type lectin domain family 7 member A (Clec7a, or Dectin-1) is a transmembrane protein containing an intracellular immunoreceptor tyrosine-based activation (ITAM)-like motif and an extracellular C-type lectin-like domain for recognition. Clec7a is expressed by macrophages and some other immune cells and is believed to control the innate immune responses to pathogens and the phagocytotic properties, through regulating phagocytosis and production of reactive oxygen species (ROS). Moreover, a recent study has shown that Clec7a is critical for macrophage polarization during renal interstitial fibrosis.

Product Information

Product Properties

Product Features

High activity, high purity, low endotoxin, high lot-to-lot consistency

Storage

Store at -25 ~ -15°C, valid for 1 year after receipt. After reconstitution, store at 2~8°C under sterile conditions, valid for 7 days. After reconstitution, store at -85 ~ -65°C under sterile conditions, valid for 3 months.

Documents:

Manuals

96588_Manual_HB20260421