Описание
Aprotinin, also known as Iniprol, is a competitive, reversible serine protease inhibitor that forms stable complexes with serine proteases, blocking the active sites of these enzymes. This binding is reversible; most Aprotinin-protease complexes dissociate under extreme pH conditions (pH<3.0). Aprotinin inhibits chymotrypsin, trypsin, plasmin, and kallikrein but does not inhibit Factor Xa and thrombin. Structurally, Aprotinin is a monomeric globular protein derived from bovine lung, consisting of 58 amino acids arranged in a single polypeptide chain with three cross-linked disulfide bonds.
Yeasen's recombinant Aprotinin is produced in E. coli under GMP regulations, free from any animal-derived components, eliminating the risk of contamination with animal-derived viruses. Its amino acid sequence is identical to that of bovine lung-derived Aprotinin, exhibiting the same enzymatic properties and can be used as a substitute for animal-derived Aprotinin in various biotechnological processes, such as inhibition of serine protease activity in recombinant protein production and cell culture.
Additionally, Yeasen offers Aprotinin sourced from bovine lung (Cat#20105ES, animal-derived).
Features
Wide Application Range: Efficiently recovers DNA fragments from 50 bp to 15 kb.
High Recovery Efficiency: Binds up to 8 μg of DNA per column.
Fast & Efficient Workflow: Purify DNA in just 10 minutes with up to 85% recovery.
Specifications
|
Source |
E. coli expression |
|
CAS No. |
9087-70-1 |
|
Appearance |
White, off-white, or off-yellow powder |
|
Solubility (5mg/ml in 0.9% NaCl) |
Soluble, clear or slightly turbid |
|
Purity |
≥95% (HPLC) |
|
Protein Content |
≥60% |
|
Enzyme Concentration |
≥3.0 EPU/mg pro |
|
Activity Definition |
Trypsin Unit: The amount of enzyme that hydrolyzes 1 μmol of N-benzoyl-L-arginine ethyl ester (BAEE) per second is defined as one trypsin unit. |
Components
|
Components No. |
Name |
20419ES03 |
20419ES10 |
|
20419 |
Aprotinin, Recombinant, Expressed in E.coli |
1 mg |
10 mg |
Shipping and Storage
This product should be stored at 2~8°C for up to 2 years.
Documents:
Safety Data Sheet
Manuals
20419_Manual_Ver.EN20250717.pdf
Citations & References:
Оплата и безопасность
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Расследование
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Продукт предназначен только для исследовательских целей и не предназначен для терапевтического или диагностического использования на людях или животных. Продукты и содержимое защищены патентами, товарными знаками и авторскими правами, принадлежащими Yeasen Biotechnology. Символы товарных знаков указывают на страну происхождения, а не обязательно на регистрацию во всех регионах.
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