Description
Macrophage colony stimulating factor 1, also known as CSF-1 and M-CSF, is a one-way membrane protein that forms homodimers or heterodimers via disulfide bonds. M-CSF is a major regulator of macrophage survival, proliferation and differentiation. M-CSF can promote monocyte survival, monocyte transformation to macrophage and macrophage proliferation.
Product Properties
|
Synonyms |
CSF-1,Lanimostim |
|
Uniprot No. |
CSF-1,Lanimostim |
|
Source |
Recombinant Human M-CSF Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Glu33-Arg255. |
|
Molecular Weight |
The protein has a predicted MW of 27.08 kDa. And it migrates as 33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
<0.01 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
|
Reconstitution |
Centrifuge tubes before opening. Dissolve lyophilized protein with sterile PBS to ensure the concentration is greater than 100 ug/mL. |
Shipping and Storage
The product should be stored at -25~-15℃ for 1 year from date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.