Recombinant Rat LPS-induced CXC Chemokine/CXCL5 (Rat LIX/CXCL5) _ 90938ES

SKU: 90938ES08

Size: 5 μg
Price:
Sale price$78.00

Shipping calculated at checkout

Stock:
In stock
Bulk Quote Inquiry

Description

CXCL5 (epithelial neutrophil-activating peptide-78) is a member of a proangiogenic subgroup of the CXC-type chemokine family of small, secreted proteins. Human CXCL5 shares 57% amino acid (aa) sequence identity with mouse and rat CXCL5. Full length CXCL5 (78 aa) is trimmed at the N-terminus by cathepsin G and chymotrypsin to ENA-74 (74 aa) and ENA-70 (70 aa), with the shortened forms showing increased potency relative to full length CXCL5. CXCL5 which acts as a potent chemoattractant and activator of neutrophil function was reported to play a multifaceted role in tumorigenesis. CXCL5 targeted therapy would prevent not only the development of type II diabetes in obese subjects, but also several other obesity-related co morbidities.

 

Product Properties

Synonyms

chemokine (C-C motif) ligand 5, C-X-C motif chemokine 5, CXCL5, CXCL5/ENA-78, Cytokine LIX, ENA-78, Neutrophil-activating peptide ENA-78, neutrophil-activating protein 78, SCYB5ENA78, Small-inducible Cytokine B5

Accession

P97885

GeneID

60665

Source

E.coli-derived rat LIX/CXCL5 protein, Ala38-Gln130.

Molecular Weight

Approximately 10.1 kDa.

AA Sequence

APFSAMVATE LRCVCLTLAP RINPKMIANL EVIPAGPHCP KVEVIAKLKN QKDNVCLDPQ APLIKKVIQK ILGSENKKTK RNALALVRSA STQ

Tag

None

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration of 10-100 ng/ml. Fully biologically active when compared to standard.

Endotoxin

< 1.0 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in 2 × PBS, pH 7.4.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20. Further dilutions should be made in appropriate buffered solutions.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

1. Avoid repeated freeze-thaw cycles.

2. For your safety and health, please wear lab coats and disposable gloves for operation.

3. For research use only!

Inquiry

You may also like