Description
Description
Interleukin 7 (IL-7) is a cytokine involved in the regulation of immune cell development and survival, including T and B lymphocytes. It is produced by stromal cells, such as fibroblasts and bone marrow stromal cells. Dysregulation of IL-7 signaling has been implicated in autoimmune diseases and cancer.
Product information
Synonyms |
Interleukin 7;IL7; IL-7; IL-7interleukin-7; interleukin 7; Lymphopoietin-1; PBGF |
Uniprot No. |
P13232 |
Source |
Recombinant Human IL-7 Protein is expressed from HEK293 Cells with His tag at the N-terminal. It contains Asp 26-His 177. |
Molecular Weight |
The protein has a predicted MW of 19.34 kDa. And it migrates as 25-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Purity |
> 95% as determined by SDS-PAGE. |
Endotoxin |
<0.1 EU per 1μg of the protein by the LAL method. |
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
Reconstitution |
Centrifuge tubes before opening. Dissolve lyophilized protein with sterile PBS to ensure the concentration is greater than 100 ug/mL. |
Storage
The product should be stored at -25~-15℃ for 1 year from date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Notes
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.