Beschrijving
Cyclophilin A (CyPA, 18 kDa) is a ubiquitously distributed protein belonging to the immunophilin family. Cyclophilin A (CyPA) is a peptidyl-prolyl cis-trans isomerase that exists in the intracellular and secretory forms and has multiple functions. Intracellular CypA takes part in folding, transport, and assembly of proteins; regulates cell proliferation; is a ligand for cyclosporine A (CsA), mediating its immune-suppressive activity; mediates signal transduction from a T cell receptor, and controls the balance of T helpers 1 and 2, inhibiting activity of T helpers 2.
Product Information
|
Product Information. |
Catalog Number |
Size |
|
Recombinant Human Cyclophilin A Protein, GST Tag |
96600ES25 |
25 μg |
|
96600ES60 |
100 μg |
|
|
96600ES76 |
500 μg |
Product Properties
|
Synonyms |
Peptidyl-prolyl cis-trans isomerase A,PPIase A,Cyclosporin A-binding protein,Rotamase A |
|
Species |
Human |
|
Expression Sequence |
Met1-Glu165,with GST Tag at the N-terminal |
|
Accession |
P62937 |
|
Tag |
N-GST Tag |
|
Expression System |
E.coli |
|
Molecular Weight |
43.5 kDa |
|
Endotoxin |
<0.1 EU/μg |
|
Formulation |
1*PBS，PH7.4 |
|
Appearance |
Lyophilized Powder |
|
Reconstitution Method |
Reconstitute at 0.1-1 mg/mL according to the size in ultrapure water after rapid centrifugation. |
Product Features
High activity, high purity, low endotoxin, high lot-to-lot consistency
Storage
Store at -25 ~ -15°C, valid for 1 year after receipt. After reconstitution, store at 2~8°C under sterile conditions, valid for 7 days. After reconstitution, store at -85 ~ -65°C under sterile conditions, valid for 3 months.
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