Beschrijving
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and it is also found in regulatory T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells.
Product Information
|
Product Information. |
Catalog Number |
Size |
|
Recombinant Rat CTLA-4/CD152 Protein,His Tag |
96596ES60 |
100 μg |
|
96596ES76 |
500 μg |
Product Properties
|
Synonyms |
CTLA4,CD152 |
|
Species |
Rat |
|
Expression Sequence |
Ile38-Asp161,with C-terminal His |
|
Accession |
Q62859 |
|
Tag |
C-His Tag |
|
Expression System |
HEK293 |
|
Molecular Weight |
19-26 kDa (Reducing) |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
< 0.1 EU/μg |
|
Formulation |
PBS, pH7.4. |
|
Appearance |
Lyophilized Powder |
|
Reconstitution Method |
Reconstitute at 0.1-1 mg/mL according to the size in ultrapure water after rapid centrifugation. |
Product Features
High activity, high purity, low endotoxin, high lot-to-lot consistency
Application Example
ELISA Data: Immobilized CTLA-4/CD152 His Tag Protein, Rat at 2.0 μg/mL (100 μL/well) can bind B7-1/CD80 Fc Chimera Protein, Mouse with EC50 of 1.36-1.57 ng/mL.
Storage
Store at -25 ~ -15°C, valid for 1 year after receipt. After reconstitution, store at 2~8°C under sterile conditions, valid for 7 days. After reconstitution, store at -85 ~ -65°C under sterile conditions, valid for 3 months.
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