Beschrijving
DCIR, also known as Lectin-like Immunoreceptor (LLIR), is a type II membrane protein belonging to the C-type lectin domain family and is designated CLEC4A. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. DCIR expressed on antigen presenting cells and granulocytes and acts as an inhibitory receptor via an intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM).
Product Information
|
Product Information. |
Catalog Number |
Size |
|
Recombinant Human CLECSF6/DCIR/CLEC4A Protein,His Tag |
96589ES60 |
100 μg |
|
96589ES76 |
500 μg |
Product Properties
|
Synonyms |
CD367 Protein,Human,CLEC4A Protein,Human,CLECSF6 Protein,Human,DCIR Protein,Human,DDB27 Protein,Human,HDCGC13P Protein,Human,LLIR Protein,Human |
|
Species |
Human |
|
Expression Sequence |
Gln70-Leu237,with N-terminal 8*His hhhhhhhhgggsQKYSQLLEKKTTKELVHTTLECVKKNMPVEETAWSCCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMKIHL |
|
Accession |
Q9UMR7 |
|
Tag |
N-His Tag |
|
Expression System |
HEK293 |
|
Molecular Weight |
23-28 kDa (Reducing) |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
< 0.1 EU/μg |
|
Formulation |
PBS, pH7.4. |
|
Appearance |
Lyophilized Powder |
|
Reconstitution Method |
Reconstitute at 0.1-1 mg/mL according to the size in ultrapure water after rapid centrifugation. |
Product Features
High activity, high purity, low endotoxin, high lot-to-lot consistency
Storage
Store at -25 ~ -15°C, valid for 1 year after receipt. After reconstitution, store at 2~8°C under sterile conditions, valid for 7 days. After reconstitution, store at -85 ~ -65°C under sterile conditions, valid for 3 months.
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