Beschrijving
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.The protein has no known natural ligand and its function is to enable optimal B-cell immune response, specifically against T-independent antigens.
Specifications
|
Synonyms |
MS4A1; CD20; MS4A-1; B1; Bp35; CD20 receptor; CD20S7; CVID5; LEU-16; Ly-44; MS4A2; S7 |
|
Species |
Human |
|
Source |
E.coli |
|
Sequence |
Ile141-Ser188 |
|
Accession |
Accession | P11836-1. |
|
Tag |
C-His-Avi |
|
Molecular Weight |
The protein has a predicted MW of 16.8 kDa same as Bis-Tris PAGE result. |
|
Endotoxin |
Less than 1EU per μg by the LAL method. |
|
Purity |
> 95% as determined by Bis-Tris PAGE |
|
Activity |
ELISA Data: Immobilized Human CD20, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Anti-CD20 Antibody, hFc Tag with the EC50 of 4.4μg/ml determined by ELISA. |
|
Formulation |
Supplied as 0.22μm filtered solution in 20mM PB, 10% Glycerol, 0.4M Urea, 1mM GSH, 0.1mM GSSG (pH 7.0). |
|
Appearance |
Liquid |
Storage
The products are shipped with ice pack and can be stored at -85~-65℃ for 1 year.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.
Note
1. For your safety and health, please wear lab coats and disposable gloves for operation.
2. For research use only!
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FAQ
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