Beschrijving
OpenCRISPR-1 is a gene editing tool designed de novo using artificial intelligence technology, with a Cas9-like protein as its core component. This protein has undergone extensive sequence re-engineering, featuring up to 400 mutations compared to the widely used SpCas9, and nearly 200 distinct differences from any known natural CRISPR-associated protein. Despite these extensive modifications, the product retains gene editing efficiency and target specificity comparable to, or even superior than, SpCas9.
Features
Protein purity: ≥95%;
Bacterial endotoxin: <10 EU/mg;
Escherichia coli host cell DNA: <3 ng/mL;
Escherichia coli host cell protein: <0.1 ppm;
Mycoplasma contamination test: negative.
No residual nuclease, nicking enzyme, RNAase, or phosphatase (<0.0001 U);
Specifications
|
Item No. |
14703ES60 / 14703ES80 |
|
Size |
100 μg / 1 mg |
|
Expression Host |
E.coli |
|
Concentration |
10 mg/mL |
|
Molecular Weight |
163.5 kDa |
|
Purity |
≥95% |
Components
|
Components No. |
Name |
14703ES60 |
14703ES80 |
|
14703-A |
OpenCRISPR-1 (10 mg/mL) |
10 μL |
100 μL |
|
14703-B |
10× Cas9 Nuclease Reaction Buffer |
500 μL |
1 mL |
Storage
This product should be stored at -25~-15℃ for 1 year.
Application
Genome editing based on CRISPR/Cas technology;
Genetic modification of cell and gene therapy products (e.g., hematopoietic stem cells, T cells);
In vitro screening of effective sgRNAs;
In vitro cleavage of target DNA.
Documents:
Safety Data Sheet
Manuals
Betaling en beveiliging
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FAQ
Het product is alleen bedoeld voor onderzoeksdoeleinden en is niet bedoeld voor therapeutisch of diagnostisch gebruik bij mensen of dieren. Producten en inhoud worden beschermd door patenten, handelsmerken en auteursrechten die eigendom zijn van
Voor bepaalde toepassingen zijn mogelijk aanvullende intellectuele eigendomsrechten van derden vereist.