Beschreibung
CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152 (Cluster of Differentiation 152 is), a protein receptor that downregulates immune responses. As a member of the immunoglobulin superfamily, CTLA-4 is expressed on the surface of helper T cells and delivers an inhibitory signal to regulate T cell activity . Structurally, the protein comprises an extracellular V domain, a transmembrane domain, and a cytoplasmic tail.
Specifications
|
Cat.No. |
96526ES25 / 96526ES60 / 96526ES76 |
|
Size |
25 μg / 100 μg / 500 μg |
Components
|
Name |
96526ES25 |
96526ES60 |
96526ES76 |
|
Recombinant Human BDCA2/DLEC4C Protein,hFc Tag |
25 μg |
100 μg |
500 μg |
Performance parameters
|
Synonyms |
Celiac Disease 3,CD152,CTLA4,CTLA-4 |
|
Species |
Mouse |
|
Expression Sequence: |
Glu36-Asp161 with His & Avi Tag at C-Terminus |
|
Accession |
P09793 |
|
Tag |
C-His-Avi Tag |
|
Expression System |
HEK293 |
|
Molecular Weight |
25-30 kDa (Reducing) |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
< 1.0 EU per μg by the LAL method. |
|
Formulation |
PBS, PH7.4, 5% trehalose |
|
Appearance |
Lyophilized Powder |
|
Reconstitution |
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
Storage
Store at -25°C to -15°C for 1 year upon receipt; after reconstitution under aseptic conditions, the product is stable for 7 days at 2°C to 8°C or for 3 months at -85°C to -65°C.
Product Features
High Activity & Purity, Low Endotoxin, High Lot-to-Lot Consistency.
Application Example
ELISA Data: Immobilized B7-1/CD80 Fc Chimera Protein,Mouse at 5.0 μg/mL (100 μL/well) can bind Biotinylated CTLA-4/CD152 His&Avi Tag Protein,Mouse with EC50 of 6.38-9.26 ng/mL.
Notes
1. This product is for research use only.
2. Please operate with lab coats and disposable gloves, for your safety.
Documents:
Manual
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