Recombinant Human IL-9 GMP Protein _ 90372ES
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Recombinant Human IL-9 GMP Protein _ 90372ES
Recombinant Human IL-9 GMP Protein _ 90372ES
IInterleukin-9 (IL-9) is primarily expressed by activated T cells. IL-9 exerts its biological effects by binding to its specific receptor, IL-9Rα. It promotes Th2-type immune responses and is involved in the pathogenesis of allergic diseases, such as asthma and atopic dermatitis. Furthermore, IL-9 supports the growth of helper T cells in an IL-2 and IL-4-independent manner, and promotes the proliferation of mast cells, erythroid progenitor cells, and other cell types. Components Name 90372ES10 90372ES50 90372ES80 Recombinant Human IL-9 GMP Protein 10 μg 50 μg 1 mg Performance Synonyms Interleukin-9, IL-9, Cytokine P40...

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Recombinant Human IL-9 GMP Protein _ 90372ES

YeasenSKU: 90372ES10
Size: 10 μg
Preis:
$265.00
Aktie:
Auf Lager

IInterleukin-9 (IL-9) is primarily expressed by activated T cells. IL-9 exerts its biological effects by binding to its specific receptor, IL-9Rα. It promotes Th2-type immune responses and is involved in the pathogenesis of allergic diseases, such as asthma and atopic dermatitis. Furthermore, IL-9 supports the growth of helper T cells in an IL-2 and IL-4-independent manner, and promotes the proliferation of mast cells, erythroid progenitor cells, and other cell types.

Components

Name

90372ES10

90372ES50

90372ES80

Recombinant Human IL-9 GMP Protein

10 μg

50 μg

1 mg

Performance

Synonyms

Interleukin-9, IL-9, Cytokine P40

Source

Human IL-9 Protein is expressed from CHO Cells.

Sequence

Gln 19 - Ile 144

Molecular Weight

The protein has a calculated MW of 14.1 kDa. The protein migrates as 40 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession

P15248

Biological Activity

The ED50 as determined by the dose-dependent stimulation of the proliferation of human M07e cells is ≤ 2.0 ng/ml.

Purity

＞95% as determined by SDS-PAGE.

Endotoxin

＜0.01 EU/μg protein as determined by LAL method.

Sterility

Negative.

Mycoplasma

Negative.

Vitro Virus

Negative.

Host Cell Protein

Less than 0.5 ng/μg when tested by ELISA.

Host Cell DNA

Less than 20 ng/mg when tested by qPCR.

Formulation

Lyophilized from 0.22μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Physical Appearance

Lyophilized Powder

Product Features

High Purity: >95%, minimizing the risk of immune responses caused by residual host cell proteins (HCPs) or DNA.

Ultra-Low Endotoxin: <10 EU/mg, reducing the risk of fever or inflammatory responses.

Batch-to-Batch Consistency: Ensures stability and reproducibility in cell culture.

Regulatory Compliance: Meets regulatory requirements for cell therapy products and supports IND applications.

Animal-Origin-Free: Free from animal viruses, pathogenic substances, and adventitious agent contamination, ensuring a high level of safety.

Figures

1. SDS- PAGE

Figure 1. Human IL-9 GMP Protein on SDS-PAGE under reduced condition. The purity is greater than 95%.

2.Cell Based Assay

Figure 2. The ED50 as determined by a cell proliferation assay using human M07e cells is less than 2.0 ng/mL.

Storage

This product should be stored at -25 ~ -15°C for 2 years. After reconstitution, store at -85 to -65°C. Valid for 3 months.

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