Beschreibung
IInterleukin-9 (IL-9) is primarily expressed by activated T cells. IL-9 exerts its biological effects by binding to its specific receptor, IL-9Rα. It promotes Th2-type immune responses and is involved in the pathogenesis of allergic diseases, such as asthma and atopic dermatitis. Furthermore, IL-9 supports the growth of helper T cells in an IL-2 and IL-4-independent manner, and promotes the proliferation of mast cells, erythroid progenitor cells, and other cell types.
Components
|
Name |
90372ES10 |
90372ES50 |
90372ES80 |
|
Recombinant Human IL-9 GMP Protein |
10 μg |
50 μg |
1 mg |
Performance parameters
|
Synonyms |
Interleukin-9, IL-9, Cytokine P40 |
|
Source |
Human IL-9 Protein is expressed from CHO Cells. |
|
Sequence |
Gln 19 - Ile 144 |
|
Molecular Weight |
The protein has a calculated MW of 14.1 kDa. The protein migrates as 40 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
|
Accession |
P15248 |
|
Biological Activity |
The ED50 as determined by the dose-dependent stimulation of the proliferation of human M07e cells is ≤ 2.0 ng/ml. |
|
Purity |
＞95% as determined by SDS-PAGE. |
|
Endotoxin |
＜0.01 EU/μg protein as determined by LAL method. |
|
Sterility |
Negative. |
|
Mycoplasma |
Negative. |
|
Vitro Virus |
Negative. |
|
Host Cell Protein |
Less than 0.5 ng/μg when tested by ELISA. |
|
Host Cell DNA |
Less than 20 ng/mg when tested by qPCR. |
|
Formulation |
Lyophilized from 0.22μm filtered solution in PBS, pH7.4 with trehalose as protectant. |
|
Physical Appearance |
Lyophilized Powder |
Storage
This product should be stored at -25 ~ -15°C for 2 years. After reconstitution, store at -85 to -65°C. Valid for 3 months.
Figure
1. SDS- PAGE
Figure 1. Human IL-9 GMP Protein on SDS-PAGE under reduced condition. The purity is greater than 95%.
2.Cell Based Assay
Figure 2. The ED50 as determined by a cell proliferation assay using human M07e cells is less than 2.0 ng/mL.
Documents:
Safety Data Sheet
Manuals
Zahlung und Sicherheit
Ihre Zahlungsinformationen werden sicher verarbeitet. Wir speichern weder Kreditkartendaten noch Zugriff auf Ihre Kreditkarteninformationen.
Sie können auch mögen
Anfrage
FAQ
Das Produkt ist nur für Forschungszwecke bestimmt und nicht für die therapeutische oder diagnostische Anwendung bei Menschen oder Tieren. Produkte und Inhalte sind durch Patente, Marken und Urheberrechte von
Für bestimmte Anwendungen sind möglicherweise zusätzliche geistige Eigentumsrechte Dritter erforderlich.