وصف
Interleukin-5 (IL-5) is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils.IL-5 is produced by mast cells, T-cells, and eosinophils, and plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors.Elevated levels of IL-5 can lead to eosinophilia, which may cause asthma and other allergic diseases. Human and mouse IL-5 are cross-species reactive.
Recombinant human IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains. This product is supplied as Fluids, high activity, high purity, low endotoxin, NO labeling.
Product Properties
|
Synonyms |
IL5; IL-5; IL-5T-cell replacing factor; interleukin 5 (colony-stimulating factor, eosinophil); interleukin-5; |
|
Species |
Mouse |
|
Source |
HEK293 Ceslls |
|
Sequence |
Met21-Gly133 |
|
Accession |
P04401 |
|
Tag |
NO |
|
Predicted molecularmass |
13.1 KDa |
|
Endotoxin |
<0.010 EU per 1 μg of the protein by the LAL method |
|
Purity |
> 95%, determined by SDS-PAGE |
|
Activity |
Measured in a cell proliferation assay using TF1 human erythroleukemic cells. The EC50 for this effect is 0.04-0.15 ng/mL. |
|
Formulation |
Dissolved in sterile PBS buffer. |
|
Appearance |
Fluids |
Shipping and Storage
-85~-65℃ storage, valid for 1 year after receipt.
Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.
Figure
Figure 1.Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The EC50 for this effect is 17-35.6 pg/mL.
Figure 2.4 ug/lane protein was resolved with SDS-PAGE under non-reducing (NR) and reducing (R) conditions and visualized by Coomassie Blue staining.
Cautions
1. For your safety and health, please wear lab coat and disposable gloves.
2. This product is for scientific research purposes only.
Payment & Security
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
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