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Anti-Payload Antibody
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Antibody-drug conjugates(ADCs) are immunoconjugates comprised of a monoclonal antibody tethered to a cytotoxic drug(known as the payload) via a chemical linker. The components that make up an ADC are a tumour antigen-specific mAb, a stable cleavable or non-cleavable chemical linker, and a potent cytotoxic payload. The Anti-Payload Antibody was used in Pharmacokinetic (PK) analysis of ADC drugs in plasma/serum, determination of drug binding affinity, DAR value analysis and efficacy evaluation of ADC drugs.
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