Interferon-gamma (IFN-γ) is an immunomodulatory protein and a member of the interferon family. Primarily produced by activated T cells, NK cells, and certain lymphocyte subsets, IFN-γ is a cytokine with diverse biological functions. It plays a critical regulatory role in immune responses by enhancing the cytotoxic capacity of macrophages and dendritic cells, promoting their release of pro-inflammatory cytokines, and regulating the expression of antigen-presenting molecules, thereby strengthening cellular immune responses. Furthermore, IFN-γ regulates T cell differentiation and function, promotes Th1 cell development, enhances B cell class switching to IgG, and maintains the balance between cellular and humoral immunity.

Features

High Purity: >95% purity to avoid immune responses caused by residual Host Cell Proteins (HCP) or DNA.

Ultra-Low Endotoxin: <10 EU/mg to minimize the risk of fever or inflammation.

Batch-to-Batch Consistency: Ensures stability and reproducibility in cell culture applications.

Regulatory Compliance: Meets regulatory requirements for cell therapy products and supports Investigational New Drug (IND) applications.

Animal-Origin Free (AOF): Free from animal viruses, pathogens, and exogenous factor contamination, ensuring maximum safety.

Components

Specifications

Storage

This product should be stored at -25~-15℃ for 3 years. After reconstitution, store at -85 to -65°C. Valid for 3 months.

Figure

SDS-PAGE

Figure 1. Human IFN-gamma GMP Protein on SDS-PAGE under reduced condition. The purity is greater than 95

SEC-HPLC

Figure 2. The purity of Human IFN-gamma GMP Protein is greater than 95% as determined by SEC-HPLC.

Cell Based Assay

Figure 3. Human IFN-gamma GMP Protein inhibits the proliferation of HT-29 cells.the specific activity of GMP Human IFN-gamma Protein is > 0.6×10^6 IU/mg, which is calibrated against human interferon gamma Standard (NIBSC code: 87/586)

Documents:

Safety Data Sheet

91224_MSDS_HB260716

Manuals

91224_Manual_HB20260716