Anti-DXD Mouse mAb _ 31902ES

SKU: 31902ES60

Size: 100 μg
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Sale price$395.00

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Description

ExatecanDXDis a synthetic derivative of the naturally occurring compound camptothecin. it binds to the topoisomerase 1-DNA complex, preventing DNA re-ligation which results in the accumulation of DNA strand breaks and ultimately leads to cell death.

Specifications

Cat.No.

31902ES60/31902ES80

Size

100 μg/1 mg

Source

Monoclonal anti-DXD antibody, is produced from a hybridoma which was obtained from a mouse immunized with DXD.

Buffer

1×PBS, pH7.4.

Type

Monoclonal Antibody

Isotype

IgG1

Host

Mouse

Concentration

1 mg/mL

Purity

98% as determined by reduced SDS-PAGE

98% as determined by non-reduced SDS-PAGE

> 98% as determined by SEC-HPLC

Activity

EC50=41.4 ng/mL by ELISA

Application

ELISA

Storage

This product should be stored at -25~-15℃ for one year, do not freeze.

 Notes

  1. This product is for research use only.
  2. Please operate with lab coats and disposable gloves, for your safety.

 

Data

SDS-PAGE

Anti-DXD mouse mAb on SDS-PAGE under reduced condition. The purity is 98.2%

Anti-DXD mouse mAb on SDS-PAGE under non-reduced condition. The purity is 98.4%.

 

SEC-HPLC

The purity of Anti-DXD mouse mAb is 99% as determined by SEC-HPLC.

 

ELISA Data

Dose response curve shows that the EC50 of Anti-DXD mouse mAb is 41.4 ng/mL.

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