Description
OpenCRISPR-1 is a gene editing tool designed de novo using artificial intelligence technology, with a Cas9-like protein as its core component. This protein has undergone extensive sequence re-engineering, featuring up to 400 mutations compared to the widely used SpCas9, and nearly 200 distinct differences from any known natural CRISPR-associated protein. Despite these extensive modifications, the product retains gene editing efficiency and target specificity comparable to, or even superior than, SpCas9.
Features
Protein purity: ≥95%;
Bacterial endotoxin: <10 EU/mg;
Escherichia coli host cell DNA: <3 ng/mL;
Escherichia coli host cell protein: <0.1 ppm;
Mycoplasma contamination test: negative.
No residual nuclease, nicking enzyme, RNAase, or phosphatase (<0.0001 U);
Specifications
|
Item No. |
14703ES60 / 14703ES80 |
|
Size |
100 μg / 1 mg |
|
Expression Host |
E.coli |
|
Concentration |
10 mg/mL |
|
Molecular Weight |
163.5 kDa |
|
Purity |
≥95% |
Components
|
Components No. |
Name |
14703ES60 |
14703ES80 |
|
14703-A |
OpenCRISPR-1 (10 mg/mL) |
10 μL |
100 μL |
|
14703-B |
10× Cas9 Nuclease Reaction Buffer |
500 μL |
1 mL |
Storage
This product should be stored at -25~-15℃ for 1 year.
Application
Genome editing based on CRISPR/Cas technology;
Genetic modification of cell and gene therapy products (e.g., hematopoietic stem cells, T cells);
In vitro screening of effective sgRNAs;
In vitro cleavage of target DNA.
Documents:
Safety Data Sheet
Manuals
Payment & Security
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Inquiry
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FAQ
The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
Certain applications may require additional third-party intellectual property rights.
Yeasen is dedicated to ethical science, believing our research should address critical questions while ensuring safety and ethical standards.