LZCap AG (3'Ma-Cy5) (25 mM) _ 10688ES

SKU: 10688ES10

Size: 50 μL
Price:
Sale price$1,000.00

Shipping calculated at checkout

Stock:
In stock
Bulk Quote Inquiry

Description

Cap AG (3' Cy5) is a Cy5 labeled cap1 analog which can track mRNA dynamics in live cells.

US patent approved.

Components

Cat No.

Name

Size

10688

LZCap AG (3' Cy5) (25 mM) 

50 μL

100 μL

Product Details

Molecular Formula

C66H84N18O30P4S2 (Free acid)

Molecular weight

1797.51(Free acid)

Concentration

25 mM

Purity

HPLC ≥90%

 

Figure

Figure 1. Cap Cy5-labeled mRNA can be used for intracellular localization analysis.  We applied SM102 LNP to deliver Cy5-LZCap capped mRNA into Huh7 cells,  the labeled mRNAs aggregated in the cell which could be readily visualized by confocal microscopy, and over time, Cy5-labeled mRNA gradually co-localized with lysosomes

Figure 2. Cap Cy5-labeled mRNA was used for cell delivery efficiency test in 293T cells. Quantitative results from flow cytometry showed the percentages of Cy5 specific 293T cells at 1h (A) and 4h (B) post transfection compared to control cells. 

Storage

This product could be stored at -25~-15 ℃ for two years.

Precautions

  1. For your safety and health, please wear personal protective equipment (PPE), such as laboratory coats and disposable gloves, when operating with this product.
  2. For research use only

Inquiry

You may also like