شرح
Contactin-2 is also known as CNTN2, TAX1 (transiently-expressed axonal glycoprotein), TAG1 (transient axonal glycoprotein), and axonin-1, and is a member of the immunoglobulin superfamily . In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region .As a neural cell adhesion molecule expressed by a subset of neuronal populations in the developing CNS and PNS, CNTN2 mediates cell-cell interactions either via homophilic, or heterophilic contacts with various adhesion molecules including NgCAM, NrCAM, NCAM and neurocan.
Product Information
|
Product Information. |
Catalog Number |
Size |
|
Recombinant Human TAG1/Contactin 2 Protein,His Tag |
96713ES60 |
100 μg |
|
96713ES76 |
500 μg |
Product Properties
|
Synonyms |
AXT, CNTN2,contactin 2 (axonal), Contactin2 |
|
Species |
Human |
|
Expression Sequence |
Ser31-Asn1012,with C-terminal His |
|
Accession |
Q02246 |
|
Tag |
C-His Tag |
|
Expression System |
HEK293 |
|
Molecular Weight |
110-130 kDa (Reducing) |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
<0.1 EU/μg |
|
Formulation |
PBS, 0.1M Arg, pH7.4. |
|
Appearance |
Lyophilized Powder |
|
Reconstitution Method |
Reconstitute at 0.1-1 mg/mL according to the size in ultrapure water after rapid centrifugation. |
Product Features
High activity, high purity, low endotoxin, high lot-to-lot consistency
Storage
Store at -25 ~ -15°C, valid for 1 year after receipt. After reconstitution, store at 2~8°C under sterile conditions, valid for 7 days. After reconstitution, store at -85 ~ -65°C under sterile conditions, valid for 3 months.
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