شرح
Transmembrane protein 27 (TMEM27/collectrin), a glycoprotein and homolog of angiotensin-converting enzyme 2 (ACE2), is a regulator of renal amino acid uptake in the proximal tubule and may have a protective role in hypertension. Mature human Collectrin consists of a 127 amino acid (aa) extracellular domain (ECD), a 21 aa transmembrane segment, and a 60 aa cytoplasmic domain. Collectrin is highly expressed in the proximal convoluted tubules of the renal collector and inhibits the proliferation of tubular epithelial cells.
Product Information
|
Product Information. |
Catalog Number |
Size |
|
Recombinant Human Collectrin/TMEM27 Protein,hFc Tag |
96591ES60 |
100 μg |
|
96591ES76 |
500 μg |
Product Properties
|
Synonyms |
NX-17 Protein,Human,NX17 Protein,Human |
|
Species |
Human |
|
Expression Sequence |
Glu15-Pro141,with C-hIgG1 Fc |
|
Accession |
Q9HBJ8 |
|
Tag |
C-hFc Tag |
|
Expression System |
HEK293 |
|
Molecular Weight |
53-60 kDa (Reducing) |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
< 0.1 EU/μg |
|
Formulation |
PBS, pH7.4. |
|
Appearance |
Lyophilized Powder |
|
Reconstitution Method |
Reconstitute at 0.1-1 mg/mL according to the size in ultrapure water after rapid centrifugation. |
Product Features
High activity, high purity, low endotoxin, high lot-to-lot consistency
Storage
Store at -25 ~ -15°C, valid for 1 year after receipt. After reconstitution, store at 2~8°C under sterile conditions, valid for 7 days. After reconstitution, store at -85 ~ -65°C under sterile conditions, valid for 3 months.
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