شرح
Interleukin-13 (IL-13) is an immunomodulatory cytokine primarily produced by activated Th2 cells, as well as mast cells and NK cells. IL-13 exerts anti-inflammatory effects on monocytes and macrophages by inhibiting the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6, and IL-8. Additionally, IL-13 enhances B cell proliferation and induces isotype switching, thereby increasing IgE production.
This recombinant mouse IL-13 is supplied as a lyophilized powder. It features high activity, high purity, low endotoxin levels, and is tag-free.
Components
|
Components No. |
Name |
90151ES05 |
90151ES10 |
90151ES50 |
90151ES60 |
90151ES76 |
|
90151 |
Recombinant Mouse IL-13 Protein |
2 μg |
10 μg |
50 μg |
100 μg |
500 μg |
Specifications
|
Synonyms |
BHR1interleukin-13, IL13, interleukin 13, MGC116786, NC30, P600 |
|
Source |
E.coli-derived Mouse IL-13, Pro22-Phe131, with an N-terminal Met. |
|
Accession |
|
|
Molecular Weight |
Approximately 12.3 kDa. |
|
AA Sequence |
MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F |
|
Endotoxin |
< 1.0 EU/μg by the LAL method. |
|
Purity |
> 97% as determined by SDS-PAGE and HPLC analyses. |
|
Biological Activity |
The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 4 ng/mL, corresponding to a specific activity of > 2.5 × 105 IU/mg. Fully biologically active when compared to standard. |
|
Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
|
Tag |
No Tag |
|
Physical Appearance |
White lyophilized powder |
Storage
This product should be stored at -25~-15℃ for 1 year. Once reconstituted under sterile conditions, it can be stored at 2 ~ 8°C for 7 days, or at -85 to -65°C for 3 months.
Reconstitution Instructions
Centrifuge the vial briefly before opening to pellet the contents at the bottom. Reconstitute with sterile deionized water or PBS to a final concentration of 0.1–1.0 mg/mL. Further dilution can be performed as needed for downstream applications. For long-term storage, it is recommended to add a carrier protein (e.g., 0.1% BSA) to the dilution buffer. After initial reconstitution, aliquot the solution into single-use portions and store at -80°C to avoid repeated freeze-thaw cycles.
Notes
1. This product is for research use only.
2. Please operate with lab coats and disposable gloves,for your safety.
Documents:
Safety Data Sheet
Manuals:
Payment & Security
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
Certain applications may require additional third-party intellectual property rights.
Yeasen is dedicated to ethical science, believing our research should address critical questions while ensuring safety and ethical standards.

