وصف
CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152 (Cluster of Differentiation 152 is), a protein receptor that downregulates immune responses. As a member of the immunoglobulin superfamily, CTLA-4 is expressed on the surface of helper T cells and delivers an inhibitory signal to regulate T cell activity . Structurally, the protein comprises an extracellular V domain, a transmembrane domain, and a cytoplasmic tail.
Specifications
|
Cat.No. |
96526ES25 / 96526ES60 / 96526ES76 |
|
Size |
25 μg / 100 μg / 500 μg |
Components
|
Name |
96526ES25 |
96526ES60 |
96526ES76 |
|
Recombinant Human BDCA2/DLEC4C Protein,hFc Tag |
25 μg |
100 μg |
500 μg |
Performance parameters
|
Synonyms |
Celiac Disease 3,CD152,CTLA4,CTLA-4 |
|
Species |
Mouse |
|
Expression Sequence: |
Glu36-Asp161 with His & Avi Tag at C-Terminus |
|
Accession |
P09793 |
|
Tag |
C-His-Avi Tag |
|
Expression System |
HEK293 |
|
Molecular Weight |
25-30 kDa (Reducing) |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
< 1.0 EU per μg by the LAL method. |
|
Formulation |
PBS, PH7.4, 5% trehalose |
|
Appearance |
Lyophilized Powder |
|
Reconstitution |
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
Storage
Store at -25°C to -15°C for 1 year upon receipt; after reconstitution under aseptic conditions, the product is stable for 7 days at 2°C to 8°C or for 3 months at -85°C to -65°C.
Product Features
High Activity & Purity, Low Endotoxin, High Lot-to-Lot Consistency.
Application Example
ELISA Data: Immobilized B7-1/CD80 Fc Chimera Protein,Mouse at 5.0 μg/mL (100 μL/well) can bind Biotinylated CTLA-4/CD152 His&Avi Tag Protein,Mouse with EC50 of 6.38-9.26 ng/mL.
Notes
1. This product is for research use only.
2. Please operate with lab coats and disposable gloves, for your safety.
Documents:
Manual
Payment & Security
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The product is for research purposes only and is not intended for therapeutic or diagnostic use in humans or animals. Products and content are protected by patents, trademarks, and copyrights owned by Yeasen Biotechnology. Trademark symbols indicate the country of origin, not necessarily registration in all regions.
Certain applications may require additional third-party intellectual property rights.
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