Differentiation and Phenotypic Regulation of PBMC-Derived Macrophages: Elucidating the Role of Core Cytokines

Differentiation and Phenotypic Regulation of PBMC-Derived Macrophages: Elucidating the Role of Core Cytokines

I. Peripheral Blood Mononuclear Cells (PBMCs) 1. Peripheral Blood Core Definition Peripheral Blood refers to blood circulating throughout the b...
Differentiation and Phenotypic Regulation of PBMC-Derived Macrophages: Elucidating the Role of Core Cytokines

Differentiation and Phenotypic Regulation of PBMC-Derived Macrophages: Elucidating the Role of Core Cytokines

I. Peripheral Blood Mononuclear Cells (PBMCs) 1. Peripheral Blood Core Definition Peripheral Blood refers to blood circulating throughout the b...
Differentiation and Phenotypic Regulation of Bone Marrow-Derived Macrophages: Elucidating the Role of Core Cytokines

Differentiation and Phenotypic Regulation of Bone Marrow-Derived Macrophages: Elucidating the Role of Core Cytokines

I. Macrophages 1. Origins of Macrophages 1) In Vivo Natural Sources The primary source is hematopoietic stem cells in the bone marrow, which...
Evolution and Molecular Classification of the Bone Morphogenetic Protein (BMP) Family

Evolution and Molecular Classification of the Bone Morphogenetic Protein (BMP) Family

Cytokines can be classified into six categories based on biological function: interleukins, interferons, tumor necrosis factors, colony-stimulating...
The Dual Role of Interferon: From Immune Defense to Mediator of Inflammatory Storm

The Dual Role of Interferon: From Immune Defense to Mediator of Inflammatory Storm

I. Overview of Cytokines Cytokines are small molecular proteins secreted by immune and non-immune cells. Through mechanisms such as autocrine and...
The Triple-High Powerhouse! Yeasen Biotech's HiActi™ Cytokines Make a Grand Entrance

The Triple-High Powerhouse! Yeasen Biotech's HiActi™ Cytokines Make a Grand Entrance

Unstable cell conditions, fluctuating experimental data... In countless late nights, have you ever blamed experimental failures on cell condition, ...
Unlocking the Power of Recombinant Human Fibronectin in CAR-T Cell Manufacturing

Unlocking the Power of Recombinant Human Fibronectin in CAR-T Cell Manufacturing

In the rapidly evolving field of CAR-T cell therapy, achieving efficient T-cell activation and viral transduction is essential for producing potent...
IL-3/SCF/FLT3L: The Core Driving System for Efficient In Vitro Expansion of HSPCs

IL-3/SCF/FLT3L: The Core Driving System for Efficient In Vitro Expansion of HSPCs

I. What Are Hematopoietic Stem Cells Hematopoietic stem cells (HSCs) are the core adult stem cells responsible for lifelong hematopoiesis in huma...
Major Breakthrough! Yeasen Biotech's GMP-Grade IL-3 Successfully Approved for FDA DMF Filing!

Major Breakthrough! Yeasen Biotech's GMP-Grade IL-3 Successfully Approved for FDA DMF Filing!

Recently, the GMP-grade recombinant human interleukin-3 (IL-3) protein independently developed by Yeasen Biotech successfully passed the Drug Maste...
GMP Grade Recombinant Human Interleukin-3 - A Key Factor in Hematopoietic Stem Cell Expansion

GMP Grade Recombinant Human Interleukin-3 - A Key Factor in Hematopoietic Stem Cell Expansion

Overview Interleukin-3 (IL-3) is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of megakaryocytes, g...
Production Accelerator: Recombinant Enterokinase and Kex2 Protease Boost Semaglutide Manufacturing Efficiency

組換えエンテロキナーゼによるセマグルチド製造の促進

2000年代初頭、GLP-1アナログは糖尿病治療に革命をもたらしました。主要なGLP-1アナログであるセマグルチドは、経口血糖降下薬との併用により、臨床試験において血糖値をコントロールし、減量を促進し、収縮期血圧を低下させ、β細胞機能を高めることが実証されています。同社の3つの製品、オゼンピッ...
Recombinant Human Serum Albumin—Serum-free media supplements

組み換えヒト血清アルブミン

—無血清培地サプリメント 1.背景 ヒト血清アルブミン(HSA)は、ヒト血漿中に最も多く含まれるタンパク質で、ホルモン、脂質、その他の物質の輸送体です。主な生理機能は、血漿の pH を調節し、血漿の浸透圧を維持することです。ヒト血清アルブミンは、585 個のアミノ酸から構成される単鎖タン...
Recombinant Human Lysozyme

組み換えヒトリゾチーム

リゾチームは、動物や人間の涙腺分泌物(または涙)、胃液、鼻粘液、卵白に存在する酵素であり、 リゾチームは主に細胞壁のN-アセチルムラミン酸とN-アセチルグルコサミンのβ-1,4-グリコシド結合を分解し、細胞壁の不溶性多糖類を可溶性糖ペプチドに分解し、細胞壁を破壊して内容物を逃がし、細菌を溶解...
Transferrin: Essential Iron-Binding Protein for Optimized Cell Growth and Organoid Culture

トランスフェリン

背景 トランスフェリン(TRF、Tf)としても知られるトランスフェリンは、消化管で吸収された鉄と赤血球の分解によって放出された鉄を運ぶ役割を担っています。トランスフェリンは、成熟した赤血球を生成するために、三価鉄複合体(Tf-Fe3+)の形で骨髄に入ります。トランスフェリンは主に血漿中に存在...

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