{"product_id":"90906","title":"Rekombinant İnsan Büyümesi Düzenlenmiş Protein-Gamma\/CXCL3 (İnsan Gro-y\/Cxcl3) _ 90906es","description":"\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eİnsan GRO alfa, GRO beta (MIP-2 alfa) ve GRO gama (MIP-2 beta), üç ayrı, alelik olmayan insan geninin ürünleridir. GRO beta ve GRO gama, GRO alfa ile sırasıyla %90 ve %86 amino asit dizisi homologluğuna sahiptir. Üç insan GRO'su da kemokinlerin alfa (CXC) alt ailesinin üyeleridir ve homologları oldukları düşünülmektedir fare KC ve MIP-2.\u003c\/span\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eÜç GRO cDNA'sı, olgun GRO'ları oluşturmak için N-terminal 34 amino asit kalıntısının kesildiği 107 amino asit öncü proteini kodlar. Amino asit dizilerinde potansiyel N-bağlı glikozilasyon bölgeleri yoktur. GRO ekspresyonu, monositlerde, fibroblastlarda, melanositlerde ve epitel hücrelerinde serum veya PDGF ve\/veya IL-1 ve TNF gibi çeşitli inflamatuar mediatörler tarafından indüklenebilir. Bazı tümör hücre hatlarında GRO sürekli olarak eksprese edilir.\u003c\/span\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eDiğer alfa kemokinlere benzer şekilde, üç GRO proteini güçlü nötrofil çekicileri ve aktivatörleridir. Ek olarak, bu kemokinler bazofillere karşı da aktiftir. Üç GRO da IL-8 reseptörü tip B'ye yüksek afiniteyle bağlanabilir.\u003c\/span\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e  \u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eÜrün \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eÖzellikler\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003cdiv class=\"tableResponsive\" data-mce-fragment=\"1\"\u003e  \u003ctable width=\"100%\" cellspacing=\"0\" data-mce-fragment=\"1\"\u003e  \u003ctbody data-mce-fragment=\"1\"\u003e  \u003ctr class=\"firstRow\" data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eEş anlamlılar\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eGRO-gama, MIP2-beta\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eKatılım\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eP19876\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eGenKimliği\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e2921\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eKaynak\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eE.coli türevi İnsan \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003eGRO-γ\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e,Ala35-Asn107.\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eMoleküler Ağırlık\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eYaklaşık 7,9 kDa\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAA Dizisi\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eEtiket\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHiçbiri\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eFiziksel Görünüm\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eSteril Filtrelenmiş Beyaz liyofilize (dondurularak kurutulmuş) toz.\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eSaflık\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u0026gt; SDS-PAGE ve HPLC analizleri ile %97.\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eBiyolojik Aktivite\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eStandartla karşılaştırıldığında tamamen biyolojik olarak aktiftir. İnsan CXCR2 transfekte edilmiş insan 293 hücreleri kullanılarak yapılan bir kemotaksi biyolojik testi ile belirlenen biyolojik aktivite 10-100 ng\/m2 konsantrasyon aralığındadır\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003eL\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e.\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eEndotoksin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u0026lt;  LAL yöntemi ile 1 μg protein başına 1 EU.\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eFormülasyon\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e20 mM PB, pH 7,4, 50 mM NaCl'de 0,2 µm filtrelenmiş konsantre çözeltiden liyofilize edildi.\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eYeniden yapılanma\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eİçeriğin dibe çökmesi için bu şişenin açılmadan önce kısa bir süre santrifüj edilmesini öneririz. 0,1% BSA içeren steril damıtılmış su veya sulu tamponda 0,1-1,0 mg\/mL konsantrasyona kadar yeniden oluşturun.Stok çözeltiler çalışma alikotlarına bölünerek ≤ -20°C'de saklanmalıdır. Daha fazla seyreltme uygun tamponlu çözeltilerde yapılmalıdır.\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003c\/tbody\u003e  \u003c\/table\u003e  \u003c\/div\u003e  \u003cp data-mce-fragment=\"1\"\u003e  \u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eNakliye ve Depolama\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eÜrünler buz torbasıyla birlikte gönderilmekte olup, \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e-\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e20\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e℃ ila -80℃\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e için \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e1\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e yıl.\u003c\/span\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eİlk kullanımda proteinin daha küçük miktarlara bölünmesi önerilir\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e  \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003eve tekrarlanan donmalardan kaçının\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003eçözülmek \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003edöngüler.\u003c\/span\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e  \u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eDikkat Edilmesi Gerekenler\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e1.Tekrarlanan dondurma-çözme döngüsünden kaçının.\u003c\/span\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e2.Kendi güvenliğiniz ve sağlığınız için lütfen operasyon sırasında laboratuvar önlüğü ve tek kullanımlık eldiven giyin.\u003c\/span\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e3.Sadece araştırma amaçlıdır.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"100 ug","offer_id":53213668114750,"sku":"90906ES60","price":565.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213668147518,"sku":"90906ES76","price":1410.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_ae34779f-37e4-4793-819f-f925c62d95a5.jpg?v=1708077079","url":"https:\/\/www.yeasenbio.com\/tr\/products\/90906","provider":"Yeasen - Leading Innovation in Molecular Enzymes and Reagents","version":"1.0","type":"link"}