{"product_id":"94102","title":"Proteina umana PDL1\/B7-H1, il suo tag","description":"\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003ePD-L1 is one of the ligands for PD-1 and plays a critical role in the regulation of T cell immunity. The PD-L1 protein belong to the B7 family of immune regulatory molecules. PD-L1 provides a molecular stop signal to the adaptive immune system helping to distinguish between self and foreign antigens. PD-L1 also plays a role in the development of immune tolerance by promoting T cell anergy and enhancing regulatory T cell development.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 class=\"p\" align=\"justify\"\u003e\n\u003cb\u003e\u003cspan\u003eSpecifications\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003ctable border=\"0\" cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"116\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cb\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"533\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003ePD-L1,CD274,B7-H1,PDCD1L1,PDCD1LG1,PDL1\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"116\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cb\u003e\u003cspan\u003eUniprot No.\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"533\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003eQ9NZQ7\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"116\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cb\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"533\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003eRecombinant Human PDL1 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Phe 19- Thr 239.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"116\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cb\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"533\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003eThe protein has a predicted MW of  26 kDa. And it migrates as an approximately 33 kDa under reducing condition in SDS-PAGE due to glycosylation.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"116\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cb\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"533\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 95% as determined by SDS-PAGE\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"116\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cb\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"533\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003e\u0026lt;1 EU per 1μg of the protein by the LAL method.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"116\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cb\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"533\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003eLyophilized from 0.22 μm filtered solution in PBS (pH 7.4).\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"116\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cb\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"533\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003eCentrifuge tubes before opening. The concentration of protein solution used for lyophilization is generally 1mg\/mL. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 μg\/mL.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 class=\"p\" align=\"justify\"\u003e\n\u003cb\u003e\u003cspan\u003eStorage\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003eThe product should be stored at -25~-15℃\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003efor 1 year from date of receipt.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003e2-7 days, 2 ~8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003e3 months, -25~-15℃ under sterile conditions after reconstitution.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 class=\"p\" align=\"justify\"\u003e\n\u003cb\u003e\u003cspan\u003eNote\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003e1.Please operate with lab coats and disposable gloves for your safety.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003e2.This product is for research use only.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cb\u003e\u003cspan\u003eProduct Data\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cb\u003e\u003cspan\u003eSDS-PAGE\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e    \u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cb\u003e\u003cspan\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/Picture2_e5643247-bfeb-4f1f-ae81-1f1ec12470b2.png?v=1742425891\"\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"center\" class=\"p\"\u003e\u003cimg height=\"258\" width=\"666\"\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\" class=\"p\"\u003e\u003cb\u003e\u003cspan\u003eBioactivity -SPR Data\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\" class=\"p\"\u003e\u003cspan\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/Picture3_18180ad2-629e-4af9-8cc5-fd0feeacf1fc.png?v=1742425933\"\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"25 ug","offer_id":53213618929982,"sku":"94102ES25","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213618962750,"sku":"94102ES60","price":490.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213618995518,"sku":"94102ES76","price":1710.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":51400697151806,"sku":"94102ES80","price":3260.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/2022080117164387_73ae8813-bf81-489e-8d2d-290cf41e37ef.jpg?v=1740982307","url":"https:\/\/www.yeasenbio.com\/it\/products\/94102","provider":"Yeasen - Leading Innovation in Molecular Enzymes and Reagents","version":"1.0","type":"link"}