{"product_id":"92300","title":"Lattogeno placentare umano ricombinante\/proteina CSH1","description":"\u003cdiv\u003e  \u003cp class=\"MsoNormal\"\u003e  \u003c\/p\u003e  \u003cp\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eIl lattogeno placentare umano (abbreviato PL o hPL), noto anche come ormone somatoprolattinico corionico 1 (abbreviato CSH1), è un membro della famiglia della prolattina\/ormone della crescita (PRL\/GH). Il PL umano condivide il 98% di identità aa con il PL dello scimpanzé e \u0026gt;85% di identità di sequenza aa con altri ormoni della crescita umani. Tuttavia, condivide solo il 25% di identità aa con il PL di topo, pecora o bovino. Il PL è espresso principalmente dalle cellule dello strato sinciziotrofoblastico della placenta, che producono quantità crescenti di PL con l'avanzare della gravidanza. La parte principale entra nella circolazione materna, dove si lega a GH2 (GH specifico della placenta) e sostituisce la funzione del GH pituitario durante la gravidanza. Piccole quantità di PL circolano nel feto. Il PL dei primati mostra un'elevata affinità per i recettori PRL e una bassa affinità per i recettori GH. La ridotta stimolazione del PL da parte dell'angiotensina 2 è associata alla restrizione della crescita intrauterina.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003ch3\u003e  \u003cb\u003e\u003cspan class=\"15\"\u003eParametri di prestazione\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan class=\"15\"\u003e\u003c\/span\u003e\u003c\/b\u003e  \u003c\/h3\u003e  \u003ctable class=\"MsoNormalTable\" border=\"0\" cellspacing=\"0\"\u003e  \u003ctbody\u003e  \u003ctr\u003e  \u003ctd width=\"201\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eSinonimi\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"384\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eCS-1; CSAchorionic somatomammotropin A; CSH1; CSH2; CSMT; FLJ75407; hCS-A; Lattogeno; PL; Lattogeno placentare;\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr\u003e  \u003ctd width=\"201\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eSpecie\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"384\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eUmano\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr\u003e  \u003ctd width=\"201\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eFonte\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"384\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eHEK293\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr\u003e  \u003ctd width=\"201\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eSequenza\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"384\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eVal27-Phe217\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr\u003e  \u003ctd width=\"201\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eAdesione\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"384\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eP0DML2\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr\u003e  \u003ctd width=\"201\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eEtichetta\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"384\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eC-suo\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr\u003e  \u003ctd width=\"201\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003ePeso molecolare\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"384\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003e24KDa\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr\u003e  \u003ctd width=\"201\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eEndotossina\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"384\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003e\u0026lt; 1 EU\/μg con il metodo LAL.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr\u003e  \u003ctd width=\"201\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003ePurezza\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"384\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003e\u0026gt; 95% come determinato da SDS-PAGE\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr\u003e  \u003ctd width=\"201\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eFormulazione\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"384\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eLiofilizzato da una soluzione filtrata a 0,2 μm di 20 mM Tris-HCl, 150 mM NaCl, pH 8,0.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr\u003e  \u003ctd width=\"201\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003eAspetto\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"384\" valign=\"center\"\u003e  \u003cp\u003e\u003cspan\u003ePolvere liofilizzata\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003c\/tbody\u003e  \u003c\/table\u003e  \u003ch3\u003e  \u003cb\u003e\u003cspan class=\"15\"\u003e\u003cspan style=\"font-family: Calibri;\"\u003eMagazzinaggio\u003c\/span\u003e\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e  \u003c\/h3\u003e  \u003cp\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eConservare a -25~-15\u003c\/span\u003e\u003cspan style=\"font-family: sans-serif;\"\u003e℃\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003e, valido per 1 anno dal ricevimento. Dopo la ricostituzione, conservare a 2~8 \u003c\/span\u003e\u003cspan style=\"font-family: sans-serif;\"\u003e°\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003eC, valido per 7 giorni. Dopo la ricostituzione, conservare a -85~-65\u003c\/span\u003e\u003cspan style=\"font-family: sans-serif;\"\u003e℃\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003e, valido per 3 mesi.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003ch3\u003e  \u003cb\u003e\u003cspan class=\"15\"\u003e\u003cspan style=\"font-family: Calibri;\"\u003eMetodo di ricostituzione\u003c\/span\u003e\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e  \u003c\/h3\u003e  \u003cp\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eCentrifugare prima dell'apertura. Utilizzare acqua distillata sterile per ricostituire la proteina liofilizzata e la concentrazione di ricostituzione deve superare 100 \u003c\/span\u003e\u003cspan style=\"font-family: sans-serif;\"\u003eio\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003eg\/mL. Non usare il vortex per favorire la dissoluzione, mescolare capovolto. Si consiglia di dividere la proteina nella quantità per ogni esperimento quando la si usa per la prima volta per evitare ripetuti congelamenti e scongelamenti.\u003c\/span\u003e\u003c\/span\u003e\u003cb\u003e\u003cspan class=\"15\"\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e  \u003ch3\u003e  \u003cb\u003e\u003cspan class=\"15\"\u003e\u003cspan style=\"font-family: Calibri;\"\u003ePrecauzioni\u003c\/span\u003e\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e  \u003c\/h3\u003e  \u003cp\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003e1. Per la vostra sicurezza e salute, indossate un camice da laboratorio e guanti monouso durante l'operazione.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e  \u003cp\u003e\u003c!-- [se !supportLists]--\u003e\u003cspan\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e2. \u003c\/span\u003e\u003c\/span\u003e\u003c!--[fine]--\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eQuesto prodotto è destinato esclusivamente alla ricerca scientifica.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e  \u003c\/span\u003e\u003c\/p\u003e  \u003c\/div\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":51118666547518,"sku":"92300ES10","price":270.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":51118666580286,"sku":"92300ES50","price":675.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/b0d1ebc8d04cdb404c5a5bacdddbb37e_53629d38-27c0-4959-b2ff-dd20d3c4a2c1.jpg?v=1736482823","url":"https:\/\/www.yeasenbio.com\/it\/products\/92300","provider":"Yeasen - Leading Innovation in Molecular Enzymes and Reagents","version":"1.0","type":"link"}