{"product_id":"92300","title":"Recombinant Human Placental Lactogen\/CSH1 Protein","description":"\u003cdiv\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eHuman placental lactogen (abbreviated PL or hPL), also known as chorionic somatoprolactin hormone 1 (abbreviated CSH1), is a member of the prolactin\/growth hormone (PRL\/GH) family. Human PL shares 98% aa identity with chimpanzee PL and \u0026gt;85% aa sequence identity with other human growth hormones. However, it shares only 25% aa identity with mouse, sheep or cattle PL. PL is mainly expressed by cells of the syncytiotrophoblast layer of the placenta, which produce increasing amounts of PL as pregnancy progresses. The main part enters the maternal circulation, where it binds to GH2 (placenta-specific GH) and replaces the function of pituitary GH during pregnancy. Small amounts of PL circulate in the fetus. Primate PL shows high affinity for PRL receptors and low affinity for GH receptors. Reduced stimulation of PL by angiotensin 2 is associated with intrauterine growth restriction.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan class=\"15\"\u003ePerformance parameters\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan class=\"15\"\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003ctable cellspacing=\"0\" border=\"0\" class=\"MsoNormalTable\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"201\"\u003e\n\u003cp\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"384\"\u003e\n\u003cp\u003e\u003cspan\u003eCS-1; CSAchorionic somatomammotropin A; CSH1; CSH2; CSMT; FLJ75407; hCS-A; Lactogen; PL; Placental Lactogen;\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"201\"\u003e\n\u003cp\u003e\u003cspan\u003eSpecies\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"384\"\u003e\n\u003cp\u003e\u003cspan\u003eHuman\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"201\"\u003e\n\u003cp\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"384\"\u003e\n\u003cp\u003e\u003cspan\u003eHEK293\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"201\"\u003e\n\u003cp\u003e\u003cspan\u003eSequence\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"384\"\u003e\n\u003cp\u003e\u003cspan\u003eVal27-Phe217\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"201\"\u003e\n\u003cp\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"384\"\u003e\n\u003cp\u003e\u003cspan\u003eP0DML2\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"201\"\u003e\n\u003cp\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"384\"\u003e\n\u003cp\u003e\u003cspan\u003eC-His\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"201\"\u003e\n\u003cp\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"384\"\u003e\n\u003cp\u003e\u003cspan\u003e24 KDa\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"201\"\u003e\n\u003cp\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"384\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1 EU\/μg by the LAL method.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"201\"\u003e\n\u003cp\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"384\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 95% as determined by SDS-PAGE\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"201\"\u003e\n\u003cp\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"384\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"201\"\u003e\n\u003cp\u003e\u003cspan\u003eAppearance\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"384\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized powder\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan class=\"15\"\u003e\u003cspan style=\"font-family: Calibri;\"\u003eStorage\u003c\/span\u003e\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eStore at -25~-15\u003c\/span\u003e\u003cspan style=\"font-family: sans-serif;\"\u003e℃\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003e, valid for 1 year after receipt. After reconstitution, store at 2~8 \u003c\/span\u003e\u003cspan style=\"font-family: sans-serif;\"\u003e°\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003eC, valid for 7 days. After reconstitution, store at -85~-65\u003c\/span\u003e\u003cspan style=\"font-family: sans-serif;\"\u003e℃\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003e, valid for 3 months.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan class=\"15\"\u003e\u003cspan style=\"font-family: Calibri;\"\u003eReconstitution method\u003c\/span\u003e\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eCentrifuge before opening. Use sterile distilled water to reconstitute the lyophilized protein, and the reconstitution concentration should exceed 100 \u003c\/span\u003e\u003cspan style=\"font-family: sans-serif;\"\u003eμ\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003eg\/mL. Do not use vortexing to assist dissolution, mix upside down. It is recommended to divide the protein into the amount for each experiment when using it for the first time to avoid repeated freezing and thawing.\u003c\/span\u003e\u003c\/span\u003e\u003cb\u003e\u003cspan class=\"15\"\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan class=\"15\"\u003e\u003cspan style=\"font-family: Calibri;\"\u003ePrecautions\u003c\/span\u003e\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003e1. For your safety and health, please wear a lab coat and disposable gloves when operating.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e2. \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eThis product is for scientific research purposes only.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":51118666547518,"sku":"92300ES10","price":270.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":51118666580286,"sku":"92300ES50","price":675.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/b0d1ebc8d04cdb404c5a5bacdddbb37e_53629d38-27c0-4959-b2ff-dd20d3c4a2c1.jpg?v=1736482823","url":"https:\/\/www.yeasenbio.com\/fa\/products\/92300","provider":"Yeasen - Leading Innovation in Molecular Enzymes and Reagents","version":"1.0","type":"link"}