{"title":"Interleukins(IL)","description":"","products":[{"product_id":"90100","title":"Recombinant Human IL-1 alpha Protein _ 90100ES","description":"\u003cdiv data-mce-fragment=\"1\" class=\"Section0\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eInterleukin-1 alpha (IL1a) is also known as  IL-1A, IL1,and is a cytokine of the interleukin-1 family. Among various species, the amino acid sequence of mature IL-1 alpha is conserved 60% to 70% and human IL-1 has been found to be biologically active on murine cell lines. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. IL-1 is a major immunoregulatory\/proinflammatory cytokine which also affects fibroblast proliferation and function and therefore it was of interest to investigate whether its constitutive expression influences the in vivo tumorigenic potential of transformed fibroblastoid cell lines\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eProduct Properties\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e \u003c\/p\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"tableResponsive\"\u003e\n\u003ctable data-mce-fragment=\"1\" width=\"562\" class=\"Table\" height=\"813\"\u003e\n\u003ctbody data-mce-fragment=\"1\"\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd style=\"width: 122.109px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 408.672px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eInterleukin-1 alpha, IL-1α, BAF, IL-1F1, LAF, LEM, preinterleukin 1 alpha, pro-interleukin-1-alpha\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd style=\"width: 122.109px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eAccession\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 408.672px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003ca data-mce-fragment=\"1\" href=\"http:\/\/www.uniprot.org\/uniprot\/P01583\" target=\"_blank\" data-mce-href=\"http:\/\/www.uniprot.org\/uniprot\/P01583\"\u003eP01583\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd style=\"width: 122.109px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eGeneID\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 408.672px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003ca data-mce-fragment=\"1\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/3552\" target=\"_blank\" data-mce-href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/3552\"\u003e3552\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd style=\"width: 122.109px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 408.672px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eE.coli-derived human IL-1alpha protein, Ser113-Ala271.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd style=\"width: 122.109px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 408.672px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eApproximately 18.0 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd style=\"width: 122.109px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eAA Sequence\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 408.672px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eSAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd style=\"width: 122.109px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eTag\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 408.672px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd style=\"width: 122.109px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003ePhysical Appearance\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 408.672px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd style=\"width: 122.109px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 408.672px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u0026gt; 97% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd style=\"width: 122.109px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eBiological Activity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 408.672px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eFully biologically active when compared to standard. The ED\u003csub data-mce-fragment=\"1\"\u003e50\u003c\/sub\u003e as determined by a cell proliferation assay using murine D10S cells is less than 1.0 pg\/mL, corresponding to a specific activity of \u0026gt; 1.0 × 10\u003csup data-mce-fragment=\"1\"\u003e9\u003c\/sup\u003e IU\/mg.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd style=\"width: 122.109px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 408.672px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u0026lt; 1.0 EU per 1\u003cspan data-mce-fragment=\"1\" style=\"font-family: 'Times New Roman', Times, serif;\" face=\"Times New Roman, Times, serif\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd style=\"width: 122.109px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 408.672px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd style=\"width: 122.109px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 408.672px;\" data-mce-fragment=\"1\" valign=\"center\"\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eShipping and Storage\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eThe products are shipped with ice pack and can be stored at -20 ℃ for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e1 month, 2 to 8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e3 months, -20 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/div\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eCaution\u003c\/b\u003e\u003cb data-mce-fragment=\"1\"\u003es\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e1.Avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e2.For your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e3.For research use only!\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eManual\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003ca href=\"https:\/\/upload.yeasen.com\/website\/doc\/90100-Recombinant%20Human%20IL-1%20alpha%20Protein-HB221025.pdf\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e90100 Manual\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":46858588717374,"sku":"90100ES10","price":90.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":46858588750142,"sku":"90100ES60","price":450.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":46858588782910,"sku":"90100ES76","price":1355.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336.jpg?v=1693295416"},{"product_id":"90101","title":"Recombinant Human IL-1 beta Protein _ 90101ES","description":"\u003cdiv class=\"Section0\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-1 beta (IL-1β) is a pro inflammatory cytokine, which is secreted by immune cells to trigger inflammation and this has been found profoundly in the lesions caused by Leishmania pathogens. IL-1 is a name that designates two pleiotropic cytokines, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2), which are the products of distinct genes. IL-1 alpha and IL-1 beta are structurally related polypeptides that share approximately 21% amino acid (aa) identity in human. Both IL-1α and IL-1β binds to the same receptor and has similar but not identical biological properties; The mature human IL1β shares 96% amino acid sequence identity with rhesus and 67%-78%  with canine, mouse and rat IL-1β.IL-1β, are known to modulate effects of neurotoxic neurotransmitters discharged during excitation or inflammation in the central nervous system (CNS).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eProduct Properties\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable class=\"Table\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 24.3555%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.2241%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-1 beta, IL-1\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003eβ\u003c\/span\u003e, IL-1, IL1B, IL-1b, IL1-BETA, IL-1F2, IL1F2IL-1 beta, interleukin-1 beta, preinterleukin 1 beta, pro-interleukin-1-beta.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 24.3555%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAccession\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.2241%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P01584\" target=\"_blank\"\u003eP01584\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 24.3555%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eGeneID\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.2241%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/3553\" target=\"_blank\"\u003e3553\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 24.3555%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.2241%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eE.coli-derived human IL-1\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003eβ\u003c\/span\u003e protein, Ala117-Ser269.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 24.3555%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.2241%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eApproximately 17.3 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 24.3555%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAA Sequence\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.2241%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eAPVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 24.3555%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eTag\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.2241%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 24.3555%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePhysical Appearance\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.2241%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 24.3555%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.2241%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 97% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 24.3555%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eBiological Activity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.2241%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe ED\u003csub\u003e50\u003c\/sub\u003e as determined by a cell proliferation assay using murine D10S cells is less than 1.0 pg\/mL, corresponding to a specific activity of \u0026gt; 1.0 × 10\u003csup\u003e9\u003c\/sup\u003e IU\/mg. Fully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 24.3555%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.2241%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1 \u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 24.3555%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.2241%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 24.3555%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.2241%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eShipping and Storage\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -20 ℃ for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1 month, 2 to 8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -20 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 align=\"justify\"\u003e\u003cstrong\u003eCautions\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003e1.Avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2.For your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3.For research use only!\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cstrong\u003eDocuments:\u003c\/strong\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eSafety Data Sheet\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e90101-_MSDS_HB260210_EN.PDF\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eManuals\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/90101ES-Manual-Ver.EN20260225.pdf?v=1772096739\"\u003e90101ES-Manual-Ver.EN20260225\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53252681204030,"sku":"90101ES10","price":90.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_b4c174e0-ee5f-41c8-b48a-b60b5937cafd.jpg?v=1693296537"},{"product_id":"90103","title":"Recombinant Human IL-2 Protein, His Tag _ 90103ES","description":"\u003cp data-mce-fragment=\"1\"\u003eThe human IL-2 protein, also known as interleukin-2, is an important cytokine that plays a vital role in regulating the immune system. It is produced by activated T cells and stimulates the proliferation and activation of various immune cells, such as T cells, B cells, and natural killer cells. IL-2 also promotes the development of immune memory and enhances the effectiveness of the immune response against infections and cancers. In addition, IL-2 has been used therapeutically in the treatment of certain diseases, such as cancer and autoimmune disorders, to boost the immune system.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eProduct information\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable data-mce-fragment=\"1\"\u003e\n\u003ctbody data-mce-fragment=\"1\"\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"207\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eSynonyms\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eInterleukin-2; T-Cell Growth Factor; TCGF; Aldesleukin\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"207\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eUniprot No.\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eP60568\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"207\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eSource\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eHEK293 cells-derived human IL-2 protein, Ala21-Thr153, with N-terminal his tag.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"207\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eMolecular Weight\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eApproximately 17.35 kDa.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"207\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003ePurity\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u0026gt; 90% as determined by SDS-PAGE.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"207\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eBiological\u003c\/b\u003e\u003c\/strong\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003e A\u003c\/b\u003e\u003c\/strong\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003ectivity\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eHuman IL-2R immobilized on CM5 chip can bind human IL-2, His tag, with an affinity constant of 3.84 x 10\u003csup data-mce-fragment=\"1\"\u003e-7\u003c\/sup\u003e M as determined in a SPR assay (Biacore 8K).\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"207\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eEndotoxin\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u0026lt; 1 EU per 1μg of the protein by the LAL method.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"207\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eFormulation\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"207\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eReconstitution\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCentrifuge tubes before opening. Dissolve lyophilized protein with PBS. Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eStorage\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThe product should be stored at -25~-15℃ for 1 year from date of receipt.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e2-7 days, 2 ~8 °C under sterile conditions after reconstitution.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e3 months, -25~-15℃ under sterile conditions after reconstitution.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eNotes\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e1.Please operate with lab coats and disposable gloves, for your safety.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e2.This product is for research use only.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003e                            \u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e                           \u003c\/strong\u003e      \u003cstrong data-mce-fragment=\"1\"\u003e                                         \u003c\/strong\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213677158718,"sku":"90103ES10","price":70.0,"currency_code":"USD","in_stock":true},{"title":"100  ug","offer_id":53213677191486,"sku":"90103ES60","price":285.0,"currency_code":"USD","in_stock":true},{"title":"500  ug","offer_id":53213677224254,"sku":"90103ES76","price":570.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_6e1db7a5-337b-46f9-86b9-eea7ab92dfec.jpg?v=1693298446"},{"product_id":"90104","title":"Recombinant Human IL-3 Protein, Flag Tag _ 90104ES","description":"\u003cdiv class=\"Section0\"\u003e\n\u003cdiv align=\"center\"\u003e\n\u003ctable class=\"MsoNormalTable\" border=\"0\" cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"434\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eProduct Name\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"143\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eCat#\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"219\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eSize\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"434\" valign=\"center\" rowspan=\"5\"\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eRecombinant Human IL-3 Protein\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"143\" valign=\"center\"\u003e\n\u003cp\u003e90104ES10\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"219\" valign=\"center\"\u003e\n\u003cp\u003e10 μg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"143\" valign=\"center\"\u003e\n\u003cp\u003e90104ES50\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"219\" valign=\"center\"\u003e\n\u003cp\u003e50 μg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"143\" valign=\"center\"\u003e\n\u003cp\u003e90104ES60\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"219\" valign=\"center\"\u003e\n\u003cp\u003e100 μg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"143\" valign=\"center\"\u003e\n\u003cp\u003e90104ES76\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"219\" valign=\"center\"\u003e\n\u003cp\u003e500 μg (5×100 μg)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"143\" valign=\"center\"\u003e\n\u003cp\u003e90104ES80\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"219\" valign=\"center\"\u003e\n\u003cp\u003e1 mg (10×100 μg)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eBackground\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eIL-3, also known as Interleukin-3, is a cytokine that is produced by activated T cells and mast cells. It plays a crucial role in regulating the growth, differentiation, and function of various cell types in the immune system. human IL-3 is an important cytokine that regulates the growth, differentiation, and function of immune cells. Its study contributes to our understanding of immune system regulation and its potential applications in immunotherapy and disease treatment.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eProduct Properties\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003ctable class=\"MsoNormalTable\" border=\"0\" cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"159\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"650\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eInterleukin-3, IL-3, Hematopoietic growth factor, MCGF, Multipotential colony-stimulating factor, P-cell-stimulating factor\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"159\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"650\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P08700\"\u003eP08700\u003c\/a\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"159\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"650\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/3562\"\u003e3562\u003c\/a\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"159\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"650\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eE.coli-derived human IL-1alpha protein, Ala20-Phe152.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"159\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"650\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eApproximately 15.0 kDa.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"159\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"650\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eAPMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"159\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"650\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"159\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eAppearance\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"650\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"159\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"650\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e5\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"159\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"650\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eThe ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by a cell proliferation assay using human TF-1 cells is less than 0.1 ng\/m\u003c\/span\u003e\u003cspan\u003eL\u003c\/span\u003e\u003cspan\u003e, corresponding to a specific activity of \u0026gt; 1.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e7\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eFully biologically active when compared to standard. \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"159\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"650\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u0026lt; \u003c\/span\u003e\u003cspan\u003e0.01\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003epe\u003c\/span\u003er 1μg of the p\u003cspan\u003erotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"159\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"650\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"159\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"650\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1\u003c\/span\u003e\u003cspan\u003e% \u003c\/span\u003e\u003cspan\u003eBSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"Section1\"\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eThe product\u003c\/span\u003e\u003cspan\u003e should\u003c\/span\u003e\u003cspan\u003e be stored at -25~\u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e15℃\u003c\/span\u003e\u003cspan\u003e for 1 year from date of receipt\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e2-7 days\u003c\/span\u003e\u003cspan\u003e, 2 ~8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003cspan\u003e  \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e3\u003c\/span\u003e\u003cspan\u003e-6\u003c\/span\u003e\u003cspan\u003e months, -\u003c\/span\u003e\u003cspan\u003e8\u003c\/span\u003e\u003cspan\u003e5~\u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e6\u003c\/span\u003e\u003cspan\u003e5℃ under sterile conditions after reconstitution.\u003c\/span\u003e\u003cspan\u003e  \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eCaution\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003es\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e1.For your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e2.For research use only.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eAssay Data\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cstrong\u003eSDS- PAGE \u003c\/strong\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cimg style=\"display: block; margin-left: auto; margin-right: auto;\" alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/90104-1.png?v=1752735915\"\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: center;\" class=\"MsoNormal\"\u003e\u003cspan\u003eThe purity of Human IL-3 is greater than 95% as determined by\u003c\/span\u003e\u003cspan\u003e SDS-PAGE.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eSEC-HPLC\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/90104-2_1.png?v=1752737968\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: center;\" class=\"MsoNormal\"\u003e\u003cspan\u003eThe purity of Human IL-3 is greater than 95% as determined by SEC-HPLC.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan\u003e\u003cbr clear=\"all\" style=\"page-break-before: always; mso-break-type: section-break;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eCell Based Assay\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003e\u003cimg style=\"display: block; margin-left: auto; margin-right: auto;\" alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/90104-3.png?v=1752735915\"\u003e \u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: center;\" class=\"MsoNormal\"\u003e\u003cspan\u003eThe ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.1 ng\/mL, \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003ecorresponding to a specific acti\u003c\/span\u003evity of \u0026gt; 1.0 × 107 IU\/mg.\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eDocuments:\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp\u003eManuals\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003ca aria-describedby=\"a11y-new-window-message\" rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/90104ES-Recombinant_Human_IL-3-HB20250710_1.pdf?v=1752736016\" target=\"_blank\"\u003e90104_Manual_Ver.EN20250708.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53209626640702,"sku":"90104ES10","price":80.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53209626673470,"sku":"90104ES60","price":340.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53209626706238,"sku":"90104ES76","price":1015.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/90104.jpg?v=1693483483"},{"product_id":"90112","title":"Recombinant Human IL-13 Protein _ 90112ES","description":"\u003cdiv class=\"Section0\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-13 (IL-13) was first recognized for its effects on B cells and monocytes, where it upregulated class II expression, promoted IgE class switching and inhibited inflammatory cytokine production. IL-13 is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. Mature human IL-13 shares approximately 58% amino acid sequence identity with mouse and rat IL-13. It has become evident that IL-13 is a key mediator in the pathogenesis of allergic inflammation, and IL-13 is key proinflammatory cytokines in asthma. The cytokines interleukin IL-13 have pleiotropic effects on a variety of cell types and impact both pathologic changes and tissue remodeling.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eProduct \u003c\/b\u003e\u003cb\u003eProperties\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" class=\"Table\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eBHR1interleukin-13, IL13, interleukin 13, MGC116786, NC30, P600\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAccession\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P35225\" target=\"_blank\"\u003eP35225\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eGeneID\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/3596\" target=\"_blank\"\u003e3596\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eE.coli-derived Human IL-13, Gly35-Asp146.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eApproximately 12.5 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAA Sequence\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eGPVPPSTALR ELIEELVNIT QNQKAPLCNG SMVWSINLTA GMYCAALESL INVSGCSAIE KTQRMLSGFC PHKVSAGQFS SLHVRDTKIE VAQFVKDLLL HLKKLFREGR FN\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eTag\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePhysical Appearance\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 97% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eBiological Activity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe ED\u003csub\u003e50\u003c\/sub\u003e as determined by a cell proliferation assay using human TF-1 cells is less than 1 ng\/mL, corresponding to a specific activity of \u0026gt; 1.0 × 10\u003csup\u003e6\u003c\/sup\u003e IU\/mg. Fully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4 with 5% trehalose.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 20 mM HCl to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003e≤\u003c\/span\u003e -20\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003e℃\u003c\/span\u003e. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eS\u003c\/b\u003e\u003cb\u003ehipping\u003c\/b\u003e\u003cb\u003e and S\u003c\/b\u003e\u003cb\u003etorage\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -20 ℃ for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1 month, 2 to 8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -20 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eCaution\u003c\/b\u003e\u003cb\u003es\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003e1.\u003c\/span\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003e2.\u003c\/span\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003e3.\u003c\/span\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":46859376722238,"sku":"90112ES10","price":170.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":46859376755006,"sku":"90112ES60","price":760.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":46859376787774,"sku":"90112ES76","price":1980.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_2e1cb486-4c16-4dff-b665-8efcfc144e30.jpg?v=1693299922"},{"product_id":"90120","title":"Recombinant Human IL-21 Protein,Flag tag _90120ES","description":"\u003cp align=\"justify\"\u003e\u003cspan\u003eHunan IL-21 protein is a molecule that is found in the immune system of individuals. It is a type of interleukin, which is a protein that helps in the communication between immune cells. IL-21 plays a crucial role in regulating the body's immune response, specifically in the development, differentiation, and function of certain immune cells, such as T cells and natural killer cells.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb data-mce-fragment=\"1\"\u003eProduct Properties\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" class=\"Table\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 21.9238%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.5026%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-21, IL-21, Za11\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 21.9238%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eUniprot No.\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.5026%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eQ9HBE4\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 21.9238%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.5026%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eHEK293 cells-derived human IL-21 protein, Gln30-Ser162, with N-terminal Flag tag.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 21.9238%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.5026%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe protein has a predicted MW of 16.5 kDa. And it migrates as 19 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 21.9238%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.5026%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 95% as determined by SDS-PAGE.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 21.9238%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.5026%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt; 0.1 EU per 1μg of the protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 21.9238%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.5026%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 21.9238%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 75.5026%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eCentrifuge tubes before opening. Dissolve lyophilized protein with PBS. Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb data-mce-fragment=\"1\"\u003eShipping and Storage\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe product should be stored at -25~-15℃ for 1 year from date of receipt.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e2-7 days, 2 ~8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -25~-15℃ under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb data-mce-fragment=\"1\"\u003eCaution\u003c\/b\u003e\u003cb data-mce-fragment=\"1\"\u003es\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1.Please operate with lab coats and disposable gloves, for your safety.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e2.This product is for research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213677060414,"sku":"90120ES10","price":115.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213677093182,"sku":"90120ES60","price":625.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213677125950,"sku":"90120ES76","price":2195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/90120.jpg?v=1693483840"},{"product_id":"90128","title":"Recombinant Human Interleukin-36 gamma, 169aa (Human IL-36¦Ã, 169aa) _ 90128ES","description":"\u003cp\u003e\u003cspan\u003eIL-36 gamma [previously called IL-1F9, IL-1 epsilon (epsilon), and IL-1H1] is a member of the IL-1 family which includes IL1 beta, IL1 alpha, IL1ra, IL18, IL36 Ra (IL1F5), IL-36 alpha (IL1F6), IL36 beta (IL1F8), IL37 (IL1F7) and IL-1F10. All family members show a 12 beta strand, beta trefoil configuration, and are believed to have arisen from a common ancestral gene. IL36 gamma is an 1822 kDa, 169 amino acid intracellular and secreted protein that contains no signal sequence, no prosegment and no potential Nlinked glycosylation sites. Human IL36 gamma (aa 18169) shares 58%, 59%, 68% and 69% aa sequence identity with mouse, rat, bovine and equine IL36 gamma, respectively, and 2357% aa sequence identity with other family members. 134 aa isoform missing aa 1953 has been reported. Highest levels of IL36 gamma are produced by Langerhans cells, keratinocytes, and stomach Chief cells and parietal cells; these cells contribute to firstline defense against pathogens in the skin, lungs and digestive tract. Its expression is induced by LPS treatment of monocytes, and by IL alpha \/ beta, IL17 or TNF alpha treatment of keratinocytes and bronchial epithelia. Skin IL-36 gamma expression is increased in contact hypersensitivity and psoriasis. It is elevated in inflammatory disorders of the lung (such as asthma) and viral infections. Lung IL36 gamma and other IL36 proteins contribute to neutrophil influx. The receptor for IL-36 gamma is a combination of IL1 Rrp2, mainly found in epithelia and keratinocytes, and the widely expressed IL1 RAcP. IL36 alpha,beta and gamma all activate NF kappa B and MAPK pathways in an IL1 Rrp2 dependent manner, and IL36 gamma induces production of inflammatory cytokines and chemokines such as CXCL8\/IL8.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd style=\"width: 23.8547%;\" valign=\"center\" data-mce-style=\"width: 23.8547%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 74.4909%;\" valign=\"center\" data-mce-style=\"width: 74.4909%;\"\u003e\n\u003cp\u003e\u003cspan\u003eIL-1RP2, IL-1 epsilon, IL-1F9, IL-1H1\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8547%;\" valign=\"center\" data-mce-style=\"width: 23.8547%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 74.4909%;\" valign=\"center\" data-mce-style=\"width: 74.4909%;\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q9NZH8\" data-mce-href=\"http:\/\/www.uniprot.org\/uniprot\/Q9NZH8\" target=\"_blank\"\u003eQ9NZH8\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8547%;\" valign=\"center\" data-mce-style=\"width: 23.8547%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 74.4909%;\" valign=\"center\" data-mce-style=\"width: 74.4909%;\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/56300\" data-mce-href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/56300\" target=\"_blank\"\u003e56300\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8547%;\" valign=\"center\" data-mce-style=\"width: 23.8547%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 74.4909%;\" valign=\"center\" data-mce-style=\"width: 74.4909%;\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived human \u003c\/span\u003e\u003cspan\u003eInterleukin-36 \u003c\/span\u003e\u003cspan\u003egamma\u003c\/span\u003e\u003cspan\u003e protein\u003c\/span\u003e\u003cspan\u003e, \u003c\/span\u003e\u003cspan\u003eMet1-Asp169, with an N-terminal Met.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8547%;\" valign=\"center\" data-mce-style=\"width: 23.8547%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 74.4909%;\" valign=\"center\" data-mce-style=\"width: 74.4909%;\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 18.7 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8547%;\" valign=\"center\" data-mce-style=\"width: 23.8547%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 74.4909%;\" valign=\"center\" data-mce-style=\"width: 74.4909%;\"\u003e\n\u003cp\u003e\u003cspan\u003eMRGTPGDADG GGRAVYQSMC KPITGTINDL NQQVWTLQGQ NLVAVPRSDS VTPVTVAVIT CKYPEALEQG RGDPIYLGIQ NPEMCLYCEK VGEQPTLQLK EQKIMDLYGQ PEPVKPFLFY RAKTGRTSTL ESVAFPDWFI ASSKRDQPII LTSELGKSYN TAFELNIND\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8547%;\" valign=\"center\" data-mce-style=\"width: 23.8547%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 74.4909%;\" valign=\"center\" data-mce-style=\"width: 74.4909%;\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8547%;\" valign=\"center\" data-mce-style=\"width: 23.8547%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 74.4909%;\" valign=\"center\" data-mce-style=\"width: 74.4909%;\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8547%;\" valign=\"center\" data-mce-style=\"width: 23.8547%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 74.4909%;\" valign=\"center\" data-mce-style=\"width: 74.4909%;\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e5\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8547%;\" valign=\"center\" data-mce-style=\"width: 23.8547%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 74.4909%;\" valign=\"center\" data-mce-style=\"width: 74.4909%;\"\u003e\n\u003cp\u003e\u003cspan\u003eFully biologically active when compared to standard. The specific activity is determined by its binding ability in a functional ELISA. Immobilized rHuIL-36γ at 1 µg\/mL can bind recombinant human IL-1 Rrp2 Fc Chimera with a range of 0.15-5 µg\/mL.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8547%;\" valign=\"center\" data-mce-style=\"width: 23.8547%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 74.4909%;\" valign=\"center\" data-mce-style=\"width: 74.4909%;\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1.0 \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8547%;\" valign=\"center\" data-mce-style=\"width: 23.8547%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 74.4909%;\" valign=\"center\" data-mce-style=\"width: 74.4909%;\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 23.8547%;\" valign=\"center\" data-mce-style=\"width: 23.8547%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 74.4909%;\" valign=\"center\" data-mce-style=\"width: 74.4909%;\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan\u003e\u003cbr clear=\"all\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-\u003c\/span\u003e\u003cspan\u003ethaw \u003c\/span\u003e\u003cspan\u003ecycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eManual\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/upload.yeasen.com\/website\/file\/20220711164246385.pdf\"\u003e\u003cspan\u003e90128ES Manual\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213676994878,"sku":"90128ES10","price":190.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213677027646,"sku":"90128ES60","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_9a936a11-8b1f-411d-9fc6-8c3d6bb05338.jpg?v=1693299949"},{"product_id":"90144","title":"Recombinant Mouse IL-4 Protein _ 90144ES","description":"\u003cdiv class=\"Section0\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eProduct Description\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a pleiotropic cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells and produced by by mast cells, activated T cells and bone marrow stromal cells. Mature human IL-4 shares 55%, 39% and 43% aa sequence identity with bovine, mouse, and rat IL-4, respectively.It is a potent cytokine produced by T cells and to a lesser extent by tumor-associated natural killer cells, basophils, and mast cells. IL-4 is a differentiation factor for transforming growth factor-beta secreting Th3. And IL-4 activates two distinct signalling pathways through tyrosine phosphorylation of Stat6, a signal transducer and activator of transcription, and of a 170K protein called 4PS.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eProduct Properties\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" class=\"Table\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-4, IL-4, BSF-1, BCDF, IL4E12, Pitrakinra\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAccession\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P07750\" target=\"_blank\"\u003eP07750\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eGeneID\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/16189\" target=\"_blank\"\u003e16189\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eE.coli-derived mouse IL-1alpha protein, His21-Ser140, with an N-terminal Met.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eApproximately 13.5 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAA Sequence\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eMHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eTag\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePhysical Appearance\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 97% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eBiological Activity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe ED\u003csub\u003e50\u003c\/sub\u003e as determined by the dose-dependant prolifiration of Murine HT-2 cells is less then 2 ng\/mL, corresponding to a Specific Activity of \u0026gt; 5 × 10\u003csup\u003e5\u003c\/sup\u003e IU\/mg. Fully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003e℃\u003c\/span\u003e. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eS\u003c\/b\u003e\u003cb\u003ehipping\u003c\/b\u003e\u003cb\u003e and S\u003c\/b\u003e\u003cb\u003etorage\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -20 ℃ for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1 month, 2 to 8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -20 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eCaution\u003c\/b\u003e\u003cb\u003es\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1.Avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2.For your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3.For research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"5 ug","offer_id":46859383832894,"sku":"90144ES08","price":75.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":46859383865662,"sku":"90144ES60","price":570.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":46859383898430,"sku":"90144ES76","price":1425.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_bac40062-c0e2-4926-b517-88c3a1870305.jpg?v=1693299959"},{"product_id":"90165","title":"Recombinant Rat IL-1 beta Protein _  90165ES","description":"\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-1 beta (IL-1β) is a pro inflammatory cytokine, which is secreted by immune cells to trigger inflammation and this has been found profoundly in the lesions caused by Leishmania pathogens. IL-1 is a name that designates two pleiotropic cytokines, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2), which are the products of distinct genes. IL-1 alpha and IL-1 beta are structurally related polypeptides that share approximately 21% amino acid (aa) identity in human. Both IL-1α and IL-1β binds to the same receptor and has similar but not identical biological properties. The mature human IL1β shares 96% amino acid sequence identity with rhesus and 67% -78% with canine, mouse and rat IL-1β.IL-1β, are known to modulate effects of neurotoxic neurotransmitters discharged during excitation or inflammation in the central nervous system (CNS).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eProduct \u003c\/b\u003e\u003cb\u003eProperties\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" class=\"Table\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-1 beta, IL-1\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003eβ\u003c\/span\u003e, IL-1, IL1B, IL-1b, IL1-BETA, IL-1F2, IL1F2IL-1 beta, interleukin-1 beta, preinterleukin 1 beta, pro-interleukin-1-beta.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAccession\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q63264\" target=\"_blank\"\u003eQ63264\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eUnigene\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRn.9869.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eE.coli-derived rat IL-1β protein, Val117-Ser268, with an N-terminal Met.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eApproximately 17.3 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAA Sequence\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eMVPIRQLHCR LRDEQQKCLV LSDPCELKAL HLNGQNISQQ VVFSMSFVQG ETSNDKIPVA LGLKGLNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKTK VEFESAQFPN WYISTSQAEH RPVFLGNSNG RDIVDFTMEP VSS\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eTag\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePhysical Appearance\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 96% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eBiological Activity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe ED\u003csub\u003e50\u003c\/sub\u003e as determined by a cell proliferation assay using murine D10S cells is less than 0.1 ng\/mL, corresponding to a specific activity of \u0026gt; 1.0 × 10\u003csup\u003e7\u003c\/sup\u003e IU\/mg. Fully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4, with 5% trehalose, 0.02% Tween-20.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003e℃\u003c\/span\u003e. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eS\u003c\/b\u003e\u003cb\u003ehipping\u003c\/b\u003e\u003cb\u003e and S\u003c\/b\u003e\u003cb\u003etorage\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -20\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003e℃\u003c\/span\u003e for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1 month, 2 to 8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -20 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eCaution\u003c\/b\u003e\u003cb\u003es\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1.Avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2.For your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3.For research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213676929342,"sku":"90165ES10","price":240.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213676962110,"sku":"90165ES60","price":995.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_31219595-c46e-4c89-8427-65138b19965a.jpg?v=1693299995"},{"product_id":"90167","title":"Recombinant Rat IL-2 Protein _ 90167ES","description":"\u003cdiv class=\"Section0\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-2 (IL-2) is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2\/IL-2R signaling is required for T- cell proliferation and other fundamental functions which are essential for the immune response. The receptor for IL-2 consists of three subunits (55 kDa IL-2Rα, 75 kDa IL-2Rβ, and 64 kDa common gamma chain γc\/IL-2Rγ) that are present on the cell surface in varying preformed complexes. Mature human IL-2 shares 56% and 66% amino acid sequence identity with mouse and rat IL-2, respectively. Human and mouse IL-2 exhibit cross-species activity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eProduct \u003c\/b\u003e\u003cb\u003eProperties\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" class=\"Table\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-2, IL-2, T-cell Growth Factor, TCGF, Aldesleukin\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAccession\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P17108\" target=\"_blank\"\u003eP17108\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eGeneID\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/116562\" target=\"_blank\"\u003e116562\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eE.coli-derived rat IL-2 protein, Ala21-Gln155.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eApproximately 15.5 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAA Sequence\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eAPTSSPAKET QQHLEQLLLD LQVLLRGIDN YKNLKLPMML TFKFYLPKQA TELKHLQCLE NELGALQRVL DLTQSKSFHL EDAGNFISNI RVTVVKLKGS ENKFECQFDD EPATVVEFLR RWIAICQSII STMTQ\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eTag\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePhysical Appearance\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 97% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eBiological Activity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe ED\u003csub\u003e50 \u003c\/sub\u003eas determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.2 ng\/mL, corresponding to a specific activity of \u0026gt; 5.0 × 10\u003csup\u003e6\u003c\/sup\u003e IU\/mg. Fully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in 10 mM sodium citrate, pH 4.0.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eS\u003c\/b\u003e\u003cb\u003ehipping\u003c\/b\u003e\u003cb\u003e and S\u003c\/b\u003e\u003cb\u003etorage\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -20 ℃ for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1 month, 2 to 8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -20 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eCaution\u003c\/b\u003e\u003cb\u003es\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli align=\"justify\"\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli align=\"justify\"\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli align=\"justify\"\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Yeasen","offers":[{"title":"5 ug","offer_id":53213676831038,"sku":"90167ES08","price":115.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213676863806,"sku":"90167ES60","price":1050.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213676896574,"sku":"90167ES76","price":2720.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_4f2e30ba-d26f-4b71-aa87-6ac511e1a594.jpg?v=1693299997"},{"product_id":"90174","title":"Recombinant Rat IL-10 _  90174ES","description":"\u003cp\u003e\u003cspan\u003eInterleukin-10 (IL-10), also known as cytokine synthesis inhibitory factor (CSIF), is the charter member of the IL-10 family of α-helical cytokines that also includes IL-19, IL-20, IL-22, IL-24, and IL-26\/AK155. \u003c\/span\u003e\u003cspan\u003eIL-10 is a 178 amino acid molecule that contains two intrachain disulfide bridges and is expressed as a 36 kDa noncovalently associated homodimer.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eMature human IL10 shares 72%86% amino acid sequence identity with bovine, canine, equine, feline, mouse, ovine, porcine, and rat IL10. IL-10, a cytokine produced by CD4+ T lymphocytes belonging to the Th-2 subset, has previously been shown to inhibit the synthesis of IFN-gamma by both T cells and NK cells.\u003c\/span\u003e\u003cspan\u003e The anti-inflammatory actions of IL-10 may be therapeutically useful either directly or through modulation of HO-1 activity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct Properties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd width=\"126\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"531\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eInterleukin-10\u003c\/span\u003e\u003cspan\u003e,\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eIL-1\u003c\/span\u003e\u003cspan\u003e0, Cytokine synthesis inhibitory factor, IL10A, TGIF, CSIF\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"126\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"531\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eP29456\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"126\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"531\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/25325\" target=\"_blank\"\u003e25325\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"126\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"531\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived rat IL-10 protein, Ser19-Asn178.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"126\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"531\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 18.6 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"126\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"531\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eSKGHSIRGDN NCTHFPVSQT HMLRELRAAF SQVKTFFQKK DQLDNILLTD SLLQDFKGYL GCQALSEMIK FYLVEVMPQA ENHGPEIKEH LNSLGEKLKT LWIQLRRCHR FLPCENKSKA VEQVKNDFNK LQDKGVYKAM NEFDIFINCI EAYVTLKMKN\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"126\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"531\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"126\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"531\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"126\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"531\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e7\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"126\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"531\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eThe ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by a cell proliferation assay using murine MC\/9-2 cells is less than 1.0 ng\/m\u003c\/span\u003e\u003cspan\u003eL\u003c\/span\u003e\u003cspan\u003e, corresponding to a specific activity of \u0026gt; 1.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e6\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eFully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"126\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"531\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; \u003c\/span\u003e\u003cspan\u003e0\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"126\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"531\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris-HCl, pH 8.0, 100 mM NaCl.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"126\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"531\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 10 mM HCl to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20\u003c\/span\u003e\u003cspan\u003e℃\u003c\/span\u003e\u003cspan\u003e. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eS\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003ehipping\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003e and S\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003etorage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCaution\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003es\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53252682187070,"sku":"90174ES10","price":210.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_9ec6cec8-0298-4cbd-b45d-e7d3b7586267.jpg?v=1693300010"},{"product_id":"90177","title":"Recombinant Rat Interleukin-17A (Rat IL-17A) _ 90177ES","description":"\u003cp\u003e\u003cspan\u003eInterleukin-17A (IL-17A), also known as CTLA-8, is a glycosylated cytokine that plays an important role in anti-microbial and chronic inflammation. The six IL-17 cytokines (IL-17A-F) are encoded by separate genes but adopt a conserved cystine knot fold. Mature rat IL-17A shares 60% and 89% amino acid sequence identity with human and mouse IL-17A, respectively. IL-17A is secreted by Th17 cells, gamma \/δ\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eT cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. It forms disulfide-linked homodimers as well as disulfide-linked heterodimers with IL-17F. IL-17A exerts its effects through the transmembrane IL-17RA in complex with IL-17RC or IL-17RD. Both IL-17RA and IL-17RC are required for responsiveness to heterodimeric IL-17A\/F. IL-17A promotes protective mucosal and epidermal inflammation in response to microbial infection. It induces chemokine production, neutrophil influx, and the production of antibacterial peptides. IL-17A\/F likewise induces neutrophil migration, but IL-17F does not. IL-17A additionally enhances the production of inflammatory mediators by rheumatoid synovial fibroblasts and contributes to TNF-alpha induced shock. In contrast, it can protect against the progression of colitis by limiting chronic inflammation. IL-17A encourages the formation of autoreactive germinal centers and exacerbates the onset and progression of experimental models of autoimmunity. IL-17A has been shown to exert either tumorigenic or anti-tumor effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eCTLA8; CTLA-8\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eQ61453\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eUnigene\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eRn.218513.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eRat IL-17A\u003c\/span\u003e\u003cspan\u003e，\u003c\/span\u003e\u003cspan\u003eAla18\u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003eSer150\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately \u003c\/span\u003e\u003cspan\u003e30.0\u003c\/span\u003e\u003cspan\u003e kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eAVLIPQSSVC PNAEANNFLQ NVKVNLKVIN SLSSKASSRR PSDYLNRSTS PWTLSRNEDP DRYPSVIWEA QCRHQRCVNA EGKLDHHMNS VLIQQEILVL KREPEKCPFT FRVEKMLVGV GCTCVSSIVR HAS\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e5\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eThe ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by inducing IL-6 secretion of murine NIH\/3T3 cells is less than 1.0 ng\/m\u003c\/span\u003e\u003cspan\u003eL\u003c\/span\u003e\u003cspan\u003e, corresponding to a specific activity of \u0026gt; 1.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e6\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eFully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; \u003c\/span\u003e\u003cspan\u003e0.1\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eEU \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein by \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 µm filtered concentrated solution in 2 × PBS, pH 6.5.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan\u003e\u003cbr clear=\"all\"\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"5 ug","offer_id":53213676732734,"sku":"90177ES08","price":75.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213676765502,"sku":"90177ES60","price":590.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_420f383c-62a6-43bf-922a-b4a099df6136.jpg?v=1693300016"},{"product_id":"90188","title":"Recombinant Human IL-7 Protein _ 90188ES","description":"\u003cp\u003e\u003cstrong\u003e\u003cb\u003eDescription\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eInterleukin 7 (IL-7) is a cytokine involved in the regulation of immune cell development and survival, including T and B lymphocytes. It is produced by stromal cells, such as fibroblasts and bone marrow stromal cells. Dysregulation of IL-7 signaling has been implicated in autoimmune diseases and cancer.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eProduct information\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"803\"\u003e\n\u003cp\u003eInterleukin 7;IL7; IL-7; IL-7interleukin-7; interleukin 7; Lymphopoietin-1; PBGF\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eUniprot No.\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"803\"\u003e\n\u003cp\u003eP13232\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"803\"\u003e\n\u003cp\u003eRecombinant Human IL-7 Protein is expressed from HEK293 Cells with His tag at the N-terminal. It contains Asp 26-His 177.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"803\"\u003e\n\u003cp\u003eThe protein has a predicted MW of 19.34 kDa. And it migrates as 25-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"803\"\u003e\n\u003cp\u003e\u0026gt; 95% as determined by SDS-PAGE.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"803\"\u003e\n\u003cp\u003e\u0026lt;0.1 EU per 1μg of the protein by the LAL method.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"803\"\u003e\n\u003cp\u003eLyophilized from 0.22 μm filtered solution in PBS (pH 7.4).\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"803\"\u003e\n\u003cp\u003eCentrifuge tubes before opening. Dissolve lyophilized protein with sterile  PBS to ensure the concentration is greater than 100 ug\/mL.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eStorage\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe product should be stored at -25~-15℃ for 1 year from date of receipt.\u003c\/p\u003e\n\u003cp\u003e2-7 days, 2 ~8 °C under sterile conditions after reconstitution.\u003c\/p\u003e\n\u003cp\u003e3 months, -25~-15℃ under sterile conditions after reconstitution.\u003c\/p\u003e\n\u003cp\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eNotes\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1.Please operate with lab coats and disposable gloves,for your safety.\u003c\/p\u003e\n\u003cp\u003e2.This product is for research use only.\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":46859402805566,"sku":"90188ES10","price":170.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":46859402871102,"sku":"90188ES60","price":700.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":46859402903870,"sku":"90188ES76","price":1745.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/90188.jpg?v=1693484090"},{"product_id":"90194","title":"Recombinant Human IL-10 Protein, His tag _ 90194ES","description":"\u003cp align=\"justify\"\u003e\u003cspan\u003eIL-10 is an anti-inflammatory cytokine. IL-10 is produced primarily by monocytes, but also secreted by T cells, macrophages, mast cells, and other cell lines. IL-10 can inhibit the secretion of cytokines such as IFN-γ, IL-2, IL-3, TNF and GM-CSF, which plays an important role in the fight against human transitional immunity. In addition, IL-10 may play a role in the clinical inhibition of organ transplantation rejection due to its immunosuppressive properties.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb data-mce-fragment=\"1\"\u003eProduct Properties\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" class=\"Table\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eCSIF;IL10\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eUniprot No.\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eP05231\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecombinant Human IL-10 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Ser19-Asn178.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe protein has a predicted MW of 19.79 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 95% as determined by SDS-PAGE.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt;0.1 EU per 1\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from 0.22 μm filtered solution in PBS (pH 7.4).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eCentrifuge tubes before opening. The concentration of protein solution used for lyophilization is generally 1mg\/mL. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 ug\/mL.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb data-mce-fragment=\"1\"\u003eShipping and Storage\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe product should be stored at -25~-15℃ for 1 year from date of receipt.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e2-7 days, 2 ~8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -25~-15℃ under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb data-mce-fragment=\"1\"\u003eCaution\u003c\/b\u003e\u003cb data-mce-fragment=\"1\"\u003es\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1.Please operate with lab coats and disposable gloves,for your safety.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e2.This product is for research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213676634430,"sku":"90194ES10","price":125.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213676667198,"sku":"90194ES60","price":610.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213676699966,"sku":"90194ES76","price":1980.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/90194.jpg?v=1693484306"},{"product_id":"90195","title":"Recombinant Human IL-5 Protein, His-Fc tag _ 90195ES","description":"\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin 5 (IL-5) is a member of the hematopoietic Th2 cytokine family and consists of 115 amino acids. Unlike other members of the cytokine family (IL-3 and GM-CSF), this glycoprotein is activated as a homologous dimer. IL-5 is secreted by Th2 cells and mast cells. Its biological activity on B cells and other cell types suggests that IL-5 is functionally important for Th2 cell activity. By binding to its receptor, IL-5 stimulates B cell growth and enhances immunoglobulin secretion. It is also a key factor in the activation of eosinophils. IL-5 has been associated with a variety of diseases, including allergic rhinitis and asthma, with substantial increases seen in circulating tissue, tracheal tissue, and a decrease in sputum eosinophils.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb data-mce-fragment=\"1\"\u003eProduct Properties\u003c\/b\u003e \u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable class=\"Table\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eTRF,Interleukin-5\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eUniprot No.\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eP05113-1\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecombinant Human IL-5 Protein is expressed from HEK293 Cells with His tag at the N-terminal and Fc tag at the C-terminal. It contains Ile20-Ser134.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe protein has a predicted MW of  45.33 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 95% as determined by SDS-PAGE.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt;0.1 EU per 1\u003cspan style=\"font-family: 'Times New Roman', Times, serif;\" face=\"Times New Roman, Times, serif\" data-mce-style=\"font-family: 'Times New Roman', Times, serif;\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from 0.22 μm filtered solution in PBS (pH 7.4).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eCentrifuge tubes before opening. The concentration of protein solution used for lyophilization is generally 1mg\/mL. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 ug\/mL.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb data-mce-fragment=\"1\"\u003eShipping and Storage\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe product should be stored at -25~-15℃ for 1 year from date of receipt.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e2-7 days, 2 ~8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -25~-15℃ under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb data-mce-fragment=\"1\"\u003eCaution\u003c\/b\u003e\u003cb data-mce-fragment=\"1\"\u003es\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1.Please operate with lab coats and disposable gloves,for your safety.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e2.This product is for research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213676536126,"sku":"90195ES10","price":125.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213676568894,"sku":"90195ES60","price":610.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213676601662,"sku":"90195ES76","price":1980.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_709e1f31-081d-46b6-b22b-ffd9e9a2963a.jpg?v=1693300043"},{"product_id":"90197","title":"Recombinant Human IL-4 Protein, His _90197ES","description":"\u003cp align=\"justify\"\u003e\u003cspan\u003eIL-4 is a protein that regulates the immune response by promoting the growth and differentiation of B cells. It also plays a role in the development of allergic reactions and asthma. IL-4 is produced by a variety of cells, including T cells and mast cells.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb\u003eProduct Properties\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" class=\"Table\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-4, IL-4, BSF-1, BCDF, IL4E12, Pitrakinra\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eUniprot No.\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eP05112\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eHuman IL-4 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains His25-Ser153.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe protein has a predicted MW of 16.05 kDa. And it migrates as 20 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 95% as determined by SDS-PAGE.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt;0.01 EU per 1\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from 0.22 μm filtered solution in PBS (pH 7.4).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eCentrifuge tubes before opening. Dissolve lyophilized protein with sterile  PBS to ensure the concentration is greater than 100 ug\/mL.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb\u003eShipping and Storage\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe product should be stored at -25~-15℃ for 1 year from date of receipt.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e2-7 days, 2 ~8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -25~-15℃ under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb\u003eCaution\u003c\/b\u003e\u003cb\u003es\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1.Please operate with lab coats and disposable gloves,for your safety.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e2.This product is for research use only.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eDocuments:\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eSafety Data Sheet\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/90197-Recombinant_Human_IL-4_Protein_His_Tag-MSDS-HB230512.pdf?v=1739772364\"\u003e\u003cu\u003e\u003cspan class=\"15\"\u003e90197 MSDS HB230512  EN.PDF\u003c\/span\u003e\u003c\/u\u003e\u003c\/a\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eManuals\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/90197ES-Recombinant_Human_IL-4_Protein_His_tag-CN20230509.pdf?v=1739772364\"\u003e\u003cu\u003e\u003cspan class=\"15\"\u003e90197_Manual_Ver.EN20230419.pdf\u003c\/span\u003e\u003c\/u\u003e\u003c\/a\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213676437822,"sku":"90197ES10","price":125.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213676470590,"sku":"90197ES60","price":610.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213676503358,"sku":"90197ES76","price":1980.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/90197.jpg?v=1693484584"},{"product_id":"90198","title":"Recombinant Human IL-23 Protein _ 90198ES","description":"\u003cp align=\"justify\"\u003e\u003cspan\u003eIL-23 is a proinflammatory, heterodimeric protein composed of two subunits: a unique p19 subunit, and a p40 subunit that is shared with IL-12. IL-23 is secreted by activated dendritic cells and macrophages, and signals though a receptor comprised of IL-23R complexed with IL-12Rβ1. IL-23 has been shown to enhance proliferation of memory T cells.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb data-mce-fragment=\"1\"\u003eProduct Properties\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" class=\"Table\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-23\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSf 21 (baculovirus)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eApparent molecular mass of 65 kDa, 43-45 kDa and 20 kDa in SDS-PAGE under reducing conditions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eAA Sequence\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eHuman IL-23 p40\u003cspan face=\"Helvetica Neue宋体\" style=\"font-family: 'Helvetica Neue宋体';\"\u003e（\u003c\/span\u003eIle23-Ser328\u003cspan face=\"Helvetica Neue宋体\" style=\"font-family: 'Helvetica Neue宋体';\"\u003e）\u003c\/span\u003e\u0026amp;Human IL-23 p19 (Ala21-Pro189, Accession # AAG37232)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eBiological Activity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eMeasured by its ability to induce IL-17 secretion by mouse splenocytes. The ED\u003csub\u003e50 \u003c\/sub\u003efor this effect is 0.05-0.3 ng\/mL..\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 95% by SDS-PAGE.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt;1.0 EU per 1μg of the protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from 0.2 μm filtered concentrated sterile solution in 20 mM MES, pH 6.0, 500 mM NaCl and 1 mM EDTA.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb data-mce-fragment=\"1\"\u003eShipping and Storage\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe product should be stored at -25~-15℃ for 1 year from date of receipt.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1 month, 2 ~8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -25~-15℃ under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb data-mce-fragment=\"1\"\u003eCaution\u003c\/b\u003e\u003cb data-mce-fragment=\"1\"\u003es\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1.Please operate with lab coats and disposable gloves,for your safety.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e2.This product is for research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213676372286,"sku":"90198ES10","price":140.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213676405054,"sku":"90198ES60","price":980.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_7be70a04-1f3f-4e6d-9a77-3113bd6936bf.jpg?v=1693300047"},{"product_id":"92131","title":"Recombinant Human CNTF Protein, His tag _92131ES","description":"\u003cp\u003e\u003cstrong\u003e\u003cb\u003eDescription\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCNTF protein is a neurotrophic factor that promotes neuronal survival and differentiation. It is involved in the regulation of various cellular processes, such as inflammation, metabolism, and immune response. CNTF has potential therapeutic applications for the treatment of neurodegenerative diseases.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eProduct information\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"207\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\"\u003e\n\u003cp\u003eHCNTF,ciliary neurotrophic factor\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"207\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eUniprot No.\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\"\u003e\n\u003cp\u003eP26441\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"207\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\"\u003e\n\u003cp\u003eRecombinant Human CNTF Protein is expressed from HEK293 Cells with His tag at the N-terminal. It contains Met1-Met200.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"207\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\"\u003e\n\u003cp\u003eThe protein has a predicted MW of 24.01 kDa. And it migrates as 25-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"207\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\"\u003e\n\u003cp\u003e\u0026gt; 95% as determined by SDS-PAGE.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"207\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\"\u003e\n\u003cp\u003e\u0026lt;0.01 EU per 1μg of the protein by the LAL method.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"207\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\"\u003e\n\u003cp\u003eLyophilized from 0.22 μm filtered solution in PBS (pH 7.4).\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"207\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"767\"\u003e\n\u003cp\u003eCentrifuge tubes before opening. Dissolve lyophilized protein with sterile  PBS to ensure the concentration is greater than 100 ug\/mL.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eStorage\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe product should be stored at -25~-15℃ for 1 year from date of receipt.\u003c\/p\u003e\n\u003cp\u003e2-7 days, 2 ~8 °C under sterile conditions after reconstitution.\u003c\/p\u003e\n\u003cp\u003e3 months, -25~-15℃ under sterile conditions after reconstitution.\u003c\/p\u003e\n\u003cp\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eNotes\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1.Please operate with lab coats and disposable gloves,for your safety.\u003c\/p\u003e\n\u003cp\u003e2.This product is for research use only.\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213675225406,"sku":"92131ES10","price":115.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213675258174,"sku":"92131ES60","price":525.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213675290942,"sku":"92131ES76","price":1385.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/1_5e281b7b-a4ce-41eb-922d-8d97c380aaa0.jpg?v=1696749215"},{"product_id":"90196","title":"Recombinant Human IL-6 Protein, His tag-90196ES","description":"\u003cp align=\"justify\"\u003e\u003cspan\u003eIL-6 is similar to other interleukins in that it has a compact globular folding structure and is held in place by two disulfide bonds. The cysteine involved in forming these two disulfide bonds is highly conserved. IL-6, expressed by a variety of cells, regulates cell growth and differentiation in various tissues and is an important pro-inflammatory and immunomodulatory cytokine.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb data-mce-fragment=\"1\"\u003eProduct Properties\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" class=\"Table\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-6,BSF2,HSF,IFNB2\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eUniprot No.\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eP05231\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecombinant Human IL-6 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Val30-Met212.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe protein has a predicted MW of 22.75 kDa. And it migrates as 25-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 95% as determined by SDS-PAGE.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt;0.1 EU per 1\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from 0.22 μm filtered solution in PBS (pH 7.4).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eConcentration\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1mg\/ml.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb data-mce-fragment=\"1\"\u003eShipping and Storage\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe product should be stored at -25~-15℃ for 1 year from date of receipt.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb data-mce-fragment=\"1\"\u003eCaution\u003c\/b\u003e\u003cb data-mce-fragment=\"1\"\u003es\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1.Please operate with lab coats and disposable gloves,for your safety.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e2.This product is for research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213674570046,"sku":"90196ES10","price":115.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213674602814,"sku":"90196ES60","price":525.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213674635582,"sku":"90196ES76","price":1385.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/90196.jpg?v=1693568042"},{"product_id":"90111","title":"Recombinant Human IL-12 Protein _ 90111ES","description":"\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct Description\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eInterleukin-12 (\u003ca name=\"OLE_LINK4\" target=\"_blank\"\u003e\u003c\/a\u003eIL-12) is a cytokine that has regulatory effects on T and natural killer (NK) cells and is composed of two disulfide-bonded subunits, p40 and p35.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eI\u003c\/span\u003e\u003cspan\u003et\u003c\/span\u003e\u003cspan\u003e is a heterodimeric cytokine produced by macrophages, mitogen stimulated- or EBV infected-B lymphocytes, keratinocytes, and probably dendritic cells, with important immunoregulatory functions in vitro and in vivo. In its role as the initiator of cell-mediated immunity, it has been suggested that IL-12 has therapeutic potential as a stimulator of cell-mediated immune responses to microbial pathogens, metastatic cancers, and viral infections such as AIDS.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eImportantly, IL-12 also inhibited secondary granuloma formation in mice presensitized with eggs demonstrating a role for the cytokine in reversing established Th2-type responses.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct Properties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" style=\"width: 27.0537%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 71.4758%;\"\u003e\n\u003cp\u003e\u003cspan\u003eInterleukin\u003c\/span\u003e\u003cspan\u003e-12\u003c\/span\u003e\u003cspan\u003e,\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eIL-12, NKSF2, CLMF p40\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 27.0537%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 71.4758%;\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P29459\" target=\"_blank\"\u003eP29459\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 27.0537%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 71.4758%;\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/3592\" target=\"_blank\"\u003e3592\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 27.0537%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 71.4758%;\"\u003e\n\u003cp\u003e\u003cspan\u003eSf21-derived human IL\u003c\/span\u003e\u003cspan\u003e-12\u003c\/span\u003e\u003cspan\u003e protein\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 27.0537%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 71.4758%;\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 41 kDa and 29 kDa under reducing conditions\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 27.0537%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 71.4758%;\"\u003e\n\u003cp\u003e\u003cspan\u003eHuIL-12 p40: Ile23 - Ser328; Accession # P29460\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003eHuIL-12 p35: Arg23 - Ser219; Accession # P29459\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 27.0537%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 71.4758%;\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 27.0537%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 71.4758%;\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 27.0537%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 71.4758%;\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 97 % by SDS-PAGE.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 27.0537%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 71.4758%;\"\u003e\n\u003cp\u003e\u003cspan\u003eMeasured in a cell proliferation assay using PHA-stimulated human T lymphoblasts. The ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e for this effect is 0.01-0.05 ng\/mL. The specific activity of rH\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eIL-12 is approximately 1.1 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e4\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e units\/μg, which is calibrated against rHuIL-12 WHO Standard (NIBSC code: 95\/544).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 27.0537%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 71.4758%;\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1.0 \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 27.0537%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 71.4758%;\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.2.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 27.0537%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 71.4758%;\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile PBS to a concentration of 0.1 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20\u003c\/span\u003e\u003cspan\u003e℃\u003c\/span\u003e\u003cspan\u003e. Further dilutions should be made in appropriately buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eS\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003ehipping\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003e and S\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003etorage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCaution\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003es\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cbr clear=\"all\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213674471742,"sku":"90111ES10","price":185.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213674504510,"sku":"90111ES60","price":790.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213674537278,"sku":"90111ES76","price":1980.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_594235fd-c6d8-4dbd-820d-46ab46fb90d0.jpg?v=1693568873"},{"product_id":"90184","title":"Recombinant Equine Interleukin-1 beta ( Equine  IL-1¦Â) _ 90184ES","description":"\u003cp\u003e\u003cspan\u003eIL-1 is a name that designates two pleiotropic cytokines, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2), which are the products of distinct genes. IL-1 alpha and IL-1 beta are structurally related polypeptides that share approximately 27% amino acid (aa) identity in equine. Both proteins are produced by a wide variety of cells in response to inflammatory agents, infections, or microbial endotoxins. While IL-1 alpha and IL-1 beta are regulated independently, they bind to the same receptor and exert identical biological effects. IL-1 RI binds directly to IL-1 alpha or IL-1 beta and then associates with IL-1R accessory protein (IL-1 R3\/IL-1 R AcP) to form a high-affinity receptor complex that is competent for signal transduction. IL-1RII has high affinity for IL-1 beta but functions as a decoy receptor and negative regulator of IL-1 beta activity. IL-1ra functions as a competitive antagonist by preventing IL-1 alpha and IL-1 beta from interacting with IL-1 RI. The equine IL-1 beta cDNA encodes a 268 aa precursor. A 115 aa propeptide is cleaved intracellularly by the cysteine protease IL-1 beta -converting enzyme (Caspase-1\/ICE) to generate the active cytokine. An alternatively spliced form of equine IL-1 beta has a deletion which encompasses the Caspase-1 cleavage site and potentially results in a membrane-associated form. The 17 kDa mature equine IL-1 beta shares 65%-\u003c\/span\u003e\u003cspan\u003e75% aa sequence identity with canine, cotton rat, feline, human, mouse, porcine, rat, and rhesus IL-1 beta.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eIL-1 beta\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q28386\" target=\"_blank\"\u003eQ28386\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/100034237\" target=\"_blank\"\u003e100034237\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived\u003c\/span\u003e\u003cspan\u003e Equine IL-1β\u003c\/span\u003e\u003cspan\u003e, Ala116-Ala268.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 17.3 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eAAMHSVNCRL RDIYHKSLVL SGACELQAVH LNGENTNQQV VFCMSFVQGE EETDKIPVAL GLKEKNLYLS CGMKDGKPTL QLETVDPNTY PKRKMEKRFV FNKMEIKGNV EFESAMYPNW YISTSQAEKS PVFLGNTRGG RDITDFIMEI TSA\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e5\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eThe ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by a cell proliferation assay using murine D10S cells is less than 20 pg\/m\u003c\/span\u003e\u003cspan\u003eL\u003c\/span\u003e\u003cspan\u003e, corresponding to a specific activity of \u0026gt; 5.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e7\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eFully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; \u003c\/span\u003e\u003cspan\u003e1.0\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eEU \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein by \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in 1 × PBS, pH 7.4, 0.1 % Tween-80.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213672407358,"sku":"90184ES10","price":265.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213672440126,"sku":"90184ES60","price":1720.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213672472894,"sku":"90184ES76","price":3790.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_a62142ca-430d-4cb4-83ef-c3d19701c405.jpg?v=1708076992"},{"product_id":"91208","title":"Recombinant Human Interferon-lambda1\/Interleukin-29 (Human IFN-¦Ë1\/IL-29) _ 91208ES","description":"\u003cp\u003e\u003cspan\u003eIFN λ1, 2, and \u003c\/span\u003e\u003cspan\u003e3\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e(also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and the interferons. All three IFN-lambdas use a distinct receptor system composed of an IFN-λR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defenses similar to, but distinct from, that of type I interferons. Recombinant Human IFN-λ1 is a 19.8 kDa protein containing 178 amino acid residues.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eCytokine Zcyto21\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eQ8IU54\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e282618\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived \u003c\/span\u003e\u003cspan\u003eHuman IFN-λ1\u003c\/span\u003e\u003cspan\u003e protein,Gly20-Thr200.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately  19.8 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eGPVPTSKPTT TGKGCHIGRF KSLSPQELAS FKKARDALEE SLKLKNWSCS SPVFPGNWDL RLLQVRERPV ALEAELALTL KVLEAAAGPA LEDVLDQPLH TLHHILSQLQ ACIQPQPTAG PRPRGRLHHW LHRLQEAPKK ESAGCLEASV TFNLFRLLTR DLKYVADGNL CLRTSTHPES T\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 97% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eFully biologically active when compared to standard. The ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is less than 5 ng\/mL, corresponding to a specific activity of \u0026gt; 2.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e5\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1 EU\/μg of protein as determined by LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-\u003c\/span\u003e\u003cspan\u003ethaw \u003c\/span\u003e\u003cspan\u003ecycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. Avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. For your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. For research use only.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"5 ug","offer_id":53213667131710,"sku":"91208ES08","price":115.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213667164478,"sku":"91208ES60","price":1125.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213667197246,"sku":"91208ES76","price":2920.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_696874f4-da40-4aae-8c0f-bdc054d79e6b.jpg?v=1708077113"},{"product_id":"90200","title":"Recombinant Human IL-12 Protein, His tag _90200ES","description":"\u003cp align=\"justify\"\u003e\u003cspan\u003eIL-12 is a cytokine protein that plays a key role in the immune system's response to infection and cancer. It stimulates the activation and proliferation of T cells and natural killer cells, and also stimulates the production of interferon-gamma, an important immune signaling molecule. IL-12 has been studied for its potential use in cancer immunotherapy and vaccine development.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e?\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica NeueËÎÌå\" style=\"font-family: 'Helvetica NeueËÎÌå';\"\u003eÐÔÄܲÎÊý\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" class=\"Table\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-12,?IL-12, NKSF, CTL Maturation Factor (TCMF), Cytotoxic Lymphocyte Maturation Factor (CLMF), TSF\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eUniprot No.\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eIL-12A:P29459-1\u003cspan face=\"˼ԴºÚÌå CN Regular\" style=\"font-family: '˼ԴºÚÌå CN Regular';\"\u003e£»\u003c\/span\u003e\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003eIL-12B:P29460-1\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecombinant Human IL-12 Protein?is expressed from HEK293 Cells with His tag at the N-terminal. IL-12A contains Arg23-Ser219. IL-12B contains Ile23-Ser328.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe protein has a predicted MW of?24.5?kDa(IL-12A)\u0026amp;36.6kDa(IL-12B). And it migrates as 35-40?kDa(IL-12A)\u0026amp;40-55kDa(IL-12B) under reducing (R) condition (SDS-PAGE) due to glycosylation.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eConcentration\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1mg\/ml.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 95% as determined by SDS-PAGE.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt;1 EU per 1¦Ìg of the protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSupplied as sterile PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e?\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica NeueËÎÌå\" style=\"font-family: 'Helvetica NeueËÎÌå';\"\u003e´¢´æÌõ¼þ\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe product?should?be stored at -25~-15¡æ?for 1 year from date of receipt.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e2-7 days, 2 ~8 ¡ãC under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -25~-15¡æ under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used?and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e?\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica NeueËÎÌå\" style=\"font-family: 'Helvetica NeueËÎÌå';\"\u003eעÒâÊÂÏî\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1.Please operate with lab coats and disposable gloves,for your?safety.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e2.This product is for research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10ug","offer_id":53209567887678,"sku":"90200ES10","price":125.0,"currency_code":"USD","in_stock":true},{"title":"100ug","offer_id":53209567920446,"sku":"90200ES60","price":625.0,"currency_code":"USD","in_stock":true},{"title":"500ug","offer_id":53209567953214,"sku":"90200ES76","price":1880.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/90200_d05ecbb0-c8bf-43f7-b946-ce1eca5dbf08.jpg?v=1708077127"},{"product_id":"90191","title":"Recombinant Human Interleukin-18 (Human IL-18) _ 90191ES","description":"\u003cp\u003e\u003cspan\u003eInterleukin-18 (IL-18), also known as IL-1F4,\u003c\/span\u003e\u003cspan\u003e is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature human IL-18 shares approximately 63% amino acid sequence identity with mouse and rat IL-18. IL-18 activation is induced by infection or tissue damage and leads to disease pathology in chronic inflammation. In the presence of IL-12 or IL-15, IL-18 enhances anti-viral Th1 immune responses by inducing IFN-gamma production and the cytolytic activity of CD8+ T cells and NK cells. IL-18 induces the antigen-independent production of IL-17 by gamma δ T cells and CD4+ T cells. IL-18 also promotes myeloid dendritic cell maturation and triggers neutrophil respiratory burst. In the absence of IL-12 or IL-15, IL-18 promotes production of the Th2 cytokines IL-4 and IL-13 by CD4+ T cells and basophils. IL-18 induces the antigen-independent production of IL-17 by gamma δ T cells and CD4+ T cells. IL-18 also promotes myeloid dendritic cell maturation and triggers neutrophil respiratory burst. In cancer, IL-18 has shown a variety of activities, including enhancing anti-tumor immunity, inhibiting or promoting angiogenesis, and promoting tumor cell metastasis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eIL-1F4\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eQ14116\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003e3606\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived Human IL-11, Tyr37-Asp193\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 1\u003c\/span\u003e\u003cspan\u003e8\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003cspan\u003e2\u003c\/span\u003e\u003cspan\u003e kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eYFGKLESKLS VIRNLNDQVL FIDQGNRPLF EDMTDSDCRD NAPRTIFIIS MYKDSQPRGM AVTISVKCEK ISTLSCENKI ISFKEMNPPD NIKDTKSDII FFQRSVPGHD NKMQFESSSY EGYFLACEKE RDLFKLILKK EDELGDRSIM FTVQNED\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 95% by SDS-PAGE analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eTest in processing.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eLess than 0.1 EU\/μg of rHuIL-18 as determined by LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered solution in PBS, pH 7.0.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1\u003c\/span\u003e\u003cspan\u003e%\u003c\/span\u003e\u003cspan\u003e BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20\u003c\/span\u003e\u003cspan\u003e℃\u003c\/span\u003e\u003cspan\u003e. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":48768525369662,"sku":"90191ES10","price":170.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":48768525402430,"sku":"90191ES60","price":680.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":48768525435198,"sku":"90191ES76","price":2035.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_b1207f0a-83d6-4649-83aa-e33d33cac17a.jpg?v=1708077130"},{"product_id":"90189","title":"Recombinant Human Interleukin-8, 72aa\/CXCL8 (Human IL-8,72aa\/CXCL8) _ 90189ES","description":"\u003cp\u003e\u003cspan\u003eInterleukin-8 (IL-8), also known as CXCL8, GCP-1, and NAP-1, is a widely expressed proinflammatory member of the CXC family of chemokines. This chemokine is secreted by a variety of cell types including monocyte\/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, and various tumor cell lines in response to inflammatory stimuli (IL1, TNF, LPS, etc). IL-8\/CXCL8 can associate into a homodimer or a heterodimer with CXCL4\/PF4 (2), and it can interact with matrix and cell surface glycosaminoglycans. \u003c\/span\u003e\u003cspan\u003eNear its N-terminus, this 8-9 kDa chemokine contains an ELR motif which is important for its angiogenic properties\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003cspan\u003e Numerous observations have established IL-8\/CXCL8 as a key mediator in neutrophil-mediated acute inflammation due to its potent actions on neutrophils. In addition\u003c\/span\u003e\u003cspan\u003e, \u003c\/span\u003e\u003cspan\u003eIL-\u003c\/span\u003e\u003cspan\u003e8\/CXCL8 has crucial roles in various pathological conditions such as chronic inflammation and cancer. \u003c\/span\u003e\u003cspan\u003eI\u003c\/span\u003e\u003cspan\u003et induces VEGF expression, vascular endothelial cell proliferation, angiogenesis, and tumor cell invasiveness\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct Properties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003e(Ser-IL-8)72, GCP\/IL-8 protein I, IL8\/NAP1 form III, LYNAP, MDNCF-c, NAF\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eP\u003c\/span\u003e\u003cspan\u003e10145\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003e3576\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived Human IL-8,72aa\/CXCL8, \u003c\/span\u003e\u003cspan\u003eSer28\u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003eSer99\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 8.\u003c\/span\u003e\u003cspan\u003e4\u003c\/span\u003e\u003cspan\u003e kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eSAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 97% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003e The ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by a chemotaxis bioassay using human CXCR2 transfected mouse BaF3 cells is less than 2 ng\/m\u003c\/span\u003e\u003cspan\u003eL\u003c\/span\u003e\u003cspan\u003e, corresponding to a specific activity of \u0026gt; 5.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e5\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eFully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1.0 \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"5 ug","offer_id":53213666738494,"sku":"90189ES08","price":75.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53403339292990,"sku":null,"price":305.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213666771262,"sku":"90189ES60","price":550.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213666804030,"sku":"90189ES76","price":1430.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_2c09032d-3ca1-41ef-a651-08638b318bbe.jpg?v=1708077135"},{"product_id":"90126","title":"Recombinant Human Interleukin-36 beta, 157aa (Human IL-36¦Â, 157aa) _ 90126ES","description":"\u003cp\u003e\u003cspan\u003eInterleukin-36 Beta Human Recombinant Shipping: Synonyms Interleukin 36 beta, interleukin 1 family member 8 (eta), Interleukin-1 homolog 2, IL1F8 (Canonical product IL-1F8a), IL-1F8 (FIL1-eta), Interleukin-1 \u003c\/span\u003e\u003cspan\u003eSuperfamily,IL1H2,MGC126880, MGC126882. Introduction Human IL-36b belongs to the IL-1 family that includes IL-1b, IL-1a, IL-1ra, IL-18, IL-36ra (IL1F5), IL-36b (IL1F8), IL-36g (IL1F9), IL-37 (IL1F7) and IL-38 (IL-1F10). The IL-1 family members display a 12 b-strand, b-trefoil configuration, and are thought to have ascended from a mutual ancestral gene. IL-36 beta is known to be actively secreted. Cells expressing IL-36 beta include resting and activated monocytes and B cells. The receptor for IL-36 beta is a blend of IL-1 Rrp2 and IL-1 RAcP. Recombinant IL-36 beta stimulates processes involving NF-kB and MAPK in an IL-1 Rrp2-dependent manner. Description IL36B Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 157 amino acids and having a molecular mass of 17.7kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct Properties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"21\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"394\"\u003e\n\u003cp\u003e\u003cspan\u003eFIL1 eta, IL-1 eta, IL-1F8, IL-1H2\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"21\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"394\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q9NZH7-2\" target=\"_blank\"\u003eQ9NZH7-2\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"21\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"381\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/27177\" target=\"_blank\"\u003e27177\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"21\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"381\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived human \u003c\/span\u003e\u003cspan\u003eInterleukin-36 \u003c\/span\u003e\u003cspan\u003ebeta protein,\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eMet1-Glu157,\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ewith an N-terminal Met.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"21\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"381\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 17.7kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"21\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"381\"\u003e\n\u003cp\u003e\u003cspan\u003eMNPQREAAPK SYAIRDSRQM VWVLSGNSLI AAPLSRSIKP VTLHLIACRD TEFSDKEKGN MVYLGIKGKD LCLFCAEIQG KPTLQLKEKN IMDLYVEKKA QKPFLFFHNK EGSTSVFQSV SYPGWFIATS TTSGQPIFLT KERGITNNTN FYLDSVE\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"21\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"381\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"21\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"381\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"21\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"381\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e7\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"21\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"381\"\u003e\n\u003cp\u003e\u003cspan\u003eFully biologically active when compared to standard. The specific activity is determined by its binding ability in a functional ELISA. Immobilized rHuIL-36β at 1 µg\/mL can bind recombinant human IL-1 Rrp2 Fc Chimera with a range of 0.15-5 µg\/mL.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"21\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"381\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1.0 \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"21\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"381\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"21\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"381\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCaution\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003es\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213666640190,"sku":"90126ES10","price":190.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213666672958,"sku":"90126ES60","price":855.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213666705726,"sku":"90126ES76","price":5055.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_4d4cd872-502b-466d-9dd9-4cc00c92bf1a.jpg?v=1708077137"},{"product_id":"90124","title":"Recombinant Human Interleukin-36 alpha, 158aa (Human IL-36¦Á, 158aa) _ 90124ES","description":"\u003cp\u003e\u003cspan\u003eHuman IL-36 alpha, previously called IL-1F6 and FIL1 epsilon  (family of IL-1 member epsilon), is a member of the IL-1 family which includes IL-1 beta, IL-1 alpha, IL-1ra, IL-18, and novel family members IL-36 Ra (IL-1F5), IL-36 beta (IL-1F8), IL-36 gamma (IL-1F9), IL-37 (IL-1F7) and IL38 (IL1F10) . All family members show a 12 beta strand, beta -trefoil configuration, and are believed to have arisen from a common ancestral gene. IL-36 alpha is an 1822 kDa, 158 amino acid (aa) intracellular and secreted protein that contains no signal sequence, no prosegment and no potential from Nlinked glycosylation sites. It can be released in response to LPS and the cell ATPinduced activation of the P2X7 receptor. A 120 aa isoform missing aa 138 has been reported. Human IL36 alpha (aa 6 158) shares 5768% aa sequence identity with mouse, rabbit, equine and bovine IL36 alpha and 2757% aa sequence identity with other novel IL1 family members. IL36 alpha is mainly found in skin and lymphoid tissues, but also in fetal brain, trachea, stomach and intestine. It is expressed by monocytes, B and T cells. The receptor for IL36 alpha is a combination of IL1 Rrp2 (also called IL1RL2 or IL1 R6), mainly found in epithelia and keratinocytes, and the widely expressed IL1\u003c\/span\u003e\u003cspan\u003e RAcP. IL-36 alpha, beta, and gamma all activate NF-kappa B and MAPK pathways in an IL1 Rrp2 dependent manner, and induce production of inflammatory cytokines and chemokines such as CXCL8\/IL-8. IL-36 alpha and other family members are overexpressed in psoriatic skin lesions, and transgenic overexpression of IL36 alpha in skin keratinocytes produces epidermal hyperplasia. IL-36 alpha is present in kidney tubule epithelia, and it is highly expressed in intubulointerstitial lesions in mouse models of chronic glomerulonephritis, lupus nephritis and diabetic nephritis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eFIL1 epsilon, IL-1 epsilon, IL-1F6, IL-1H1\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q9UHA7\" target=\"_blank\"\u003eQ9UHA7\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/27179\" target=\"_blank\"\u003e27179\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived human IL-36 \u003c\/span\u003e\u003cspan\u003ealpha\u003c\/span\u003e\u003cspan\u003e protein, Met1-Phe158.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 17.7 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eMEKALKIDTP QQGSIQDINH RVWVLQDQTL IAVPRKDRMS PVTIALISCR HVETLEKDRG NPIYLGLNGL NLCLMCAKVG DQPTLQLKEK DIMDLYNQPE PVKSFLFYHS QSGRNSTFES VAFPGWFIAV SSEGGCPLIL TQELGKANTT DFGLTMLF\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e5\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eFully biologically active when compared to standard. The specific activity determined by its ability in a functional ELISA. Immobilized rHuIL-36α at 1 µg\/mL can bind recombinant human IL-1 Rrp2 Fc Chimera with a range of 0.15-5 µg\/mL.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1μg of the protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in 2 × PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-\u003c\/span\u003e\u003cspan\u003ethaw \u003c\/span\u003e\u003cspan\u003ecycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213666541886,"sku":"90124ES10","price":190.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213666574654,"sku":"90124ES60","price":855.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213666607422,"sku":"90124ES76","price":5055.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_9d8987f4-834f-4110-b3c2-aecce22f4270.jpg?v=1708077139"},{"product_id":"90123","title":"Recombinant Human Interleukin-33 (Human IL-33) _ 90123ES","description":"\u003cp\u003e\u003cspan\u003eIL-33, also known as NF-HEV and DVS 27, is a 30 kDa proinflammatory protein that may also regulate gene transcription. DVS 27 was identifed as a gene that is upregulated in vasospastic cerebral arteries. NFHEV was described as a nuclear factor that is preferentially expressed in the endothelial cells of high endothelial venules relative to endothelial cells from other tissues. IL33 was identified based on sequence and structural homology with IL1 family cytokines. DVS 27, NFHEV, and IL33 share 100% amino acid sequence identity. IL33 is constitutively expressed in smooth muscle and airway epithelia. It is up-regulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL1 alpha or IL1 beta stimulation. Similar to IL1, IL33 can be cleaved \u003c\/span\u003e\u003cem\u003e\u003cspan\u003ein vitro\u003c\/span\u003e\u003c\/em\u003e\u003cspan\u003e by caspase1, generating an Nterminal fragment that is slightly shorter than the Cterminal fragment. The Nterminal portion of full length IL33 contains a predicted bipartite nuclear localization sequence and a homeodomainlike helixturnhelix DNA binding domain. By immunofluorescence, full length IL33 localizes to the nucleus in HUVECs and transfectants. The Cterminal fragment, corresponding to mature IL33, binds and triggers signaling through mast cell IL1 R4\/ST2L, a longtime orphan receptor involved in the augmentation of Th2 cell responses. A ternary signaling complex is formed by the subsequent association of IL33 and ST2L with IL1R AcP . Stimulation of Th2 polarized lymphocytes with mature IL33 in vitro induces IL5 and IL13 secretion. In vivo administration of mature IL33 promotes increased production of IL5, IL13, IgE, and IgA, as well as splenomegaly and inflammatory infiltration of mucosal tissues . Full length and mature human IL33 share\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e5258% aa sequence identity with mouse and rat IL33. Human IL33 shares less than 20% aa sequence identity with other IL1 family proteins.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eIL-1F11, NF-HEV, DVS 27\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/O95760\" target=\"_blank\"\u003eO95760\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/90865\" target=\"_blank\"\u003e90865\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived human IL-33 protein, Ser112-Thr270.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 17.9 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSITGISPITE YLASLSTYND QSITFALEDE SYEIYVEDLK KDEKKDKVLL SYYESQHPSN ESGDGVDGKM LMVTLSPTKD FWLHANNKEH SVELHKCEKP LPDQAFFVLH NMHSNCVSFE CKTDPGVFIG VKDNHLALIK VDSSENLCTE NILFKLSET\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e7\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eFully biologically active when compared to standard. The ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by a cell proliferation assay using murine D10S cells is less than \u003c\/span\u003e\u003cspan\u003e0.05\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eng\/mL of corresponding to a specific activity of \u0026gt; 2.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e7\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1.0 \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-\u003c\/span\u003e\u003cspan\u003ethaw \u003c\/span\u003e\u003cspan\u003ecycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":48768526418238,"sku":"90123ES10","price":115.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":48768526451006,"sku":"90123ES60","price":475.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":48768526483774,"sku":"90123ES76","price":1425.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_4ebc2fad-e316-41ee-83d2-b5cfc06fabff.jpg?v=1708077143"},{"product_id":"90122","title":"Recombinant Human Interleukin-31 (Human IL-31) _ 90122ES","description":"\u003cp\u003e\u003cspan\u003eHuman Interleukin-31 (IL-31) is a 24 kDa, short-chain member of the alpha -helical family of cytokines. The human IL-31 cDNA encodes a 164 amino acid (aa) precursor that contains a 23 aa signal peptide and a 141 aa mature protein. The mature region shows four alpha -helices which would be expected to show a typical upupdowndown topology. Human and mouse IL-31 share 24% aa sequence identity in the mature region. IL-31 is mainly associated with activated T cells and preferentially expressed by Th2 rather than Th1 cells. IL-31 signals via a heterodimeric receptor complex composed of a 120 kDa, gp130-related molecule termed IL31 RA (also GPL and GLM-R) and the 180 kDa oncostatin M receptor (OSM R beta ). In the complex, IL-31 directly binds to GPL, not OSM R. IL-31 signaling has been shown to involve the Jak\/STAT pathway, the PI3 kinase\/AKT cascade, and the MAP kinase pathway. Although multiple isoforms of IL-31 RA are known, only a form that contains the entire length of the cytoplasmic domain is signaling-capable. The IL-31 receptor is constitutively expressed by keratinocytes and upregulated by IFN-gamma on monocytes. Studies using transgenic mice indicate that IL-31 may contribute to the pruritis (itching) associated with nonatopic dermatitis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eIL-31\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q6EBC2\" target=\"_blank\"\u003eQ6EBC2\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/386653\" target=\"_blank\"\u003e386653\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived human IL-31 protein, Ser24-Thr164.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 15.8 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e7\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eFully biologically active when compared to standard. The specific activity is determined by inducing STAT3 activation using human U-87 MG cells. 5 ng\/mL of rHuIL-31 can effectively induce STAT3 activation.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1.0 \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-\u003c\/span\u003e\u003cspan\u003ethaw \u003c\/span\u003e\u003cspan\u003ecycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213666443582,"sku":"90122ES10","price":170.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213666476350,"sku":"90122ES60","price":760.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213666509118,"sku":"90122ES76","price":1905.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_eb8181fa-fda8-4ce7-9b1b-41e3a622ed3f.jpg?v=1708077146"},{"product_id":"90121","title":"Recombinant Human IL-22 Protein _ 90121ES","description":"\u003cdiv class=\"Section0\"\u003e\n\u003cdiv class=\"Section0\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-22 (IL-22), also known as IL-10-related T cell-derived inducible factor (IL-TIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Human IL-22 cDNA encodes a 179 amino acid (aa) residue protein with a putative 33 aa signal peptide that is cleaved to generate a 147 aa mature protein that shares approximately 79% and 22% aa sequence identity with mouse IL-22 and human IL-10, respectively. The human IL-22 gene is localized to chromosome 12q15. Although it exists as a single copy gene in human and in many mouse strains, the mouse IL-22 gene is duplicated in some mouse strains including C57B1\/6, FVB and 129. The two mouse genes designated IL-TIF alpha and IL-TIF beta, share greater than 98% sequence homology in their coding region. IL-22 has been shown to activate STAT1 and STAT-3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal T cells upon anti-CD3 stimulation in humans. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10R beta (previously known as CRF2-4), belonging to the class II cytokine receptor family.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eProduct \u003c\/b\u003e\u003cb\u003eProperties\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable class=\"Table\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eCytokine Zcyto 18, TIF\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAccession\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q9GZX6\" target=\"_blank\"\u003eQ9GZX6\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eGeneID\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/50616\" target=\"_blank\"\u003e50616\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eE.coli-derived human IL-22 protein,Ala34-Ile179.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eApproximately 33.6 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAA Sequence\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eMAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eTag\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePhysical Appearance\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 97% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eBiological Activity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eFully biologically active when compared to standard. The ED\u003csub\u003e50\u003c\/sub\u003e as determined by inducing IL-10 secretion of human COLO 205 cells is less than 0.3 ng\/ml, corresponding to a specific activity of \u0026gt; 3.3 × 10\u003csup\u003e6 \u003c\/sup\u003eIU\/mg.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1\u003cspan face=\"Times New Roman, Times, serif\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 5.0.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eShipping and Storage\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -20\u003cspan face=\"Times New Roman, Times, serif\"\u003e℃\u003c\/span\u003e for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1 month, 2 to 8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -20 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eCaution\u003c\/b\u003e\u003cb\u003es\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1.Avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2.For your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3.For research use only.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213666345278,"sku":"90121ES10","price":170.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213666378046,"sku":"90121ES60","price":760.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213666410814,"sku":"90121ES76","price":1905.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_722e30fe-7714-438c-bad2-14c875b13f5d.jpg?v=1708077150"},{"product_id":"90119","title":"Recombinant Human Interleukin-20 (Human IL-20) _ 90119ES","description":"\u003cp\u003e\u003cspan\u003eIL-\u003c\/span\u003e\u003cspan\u003e20 belongs to the IL-10 family. It is a cytokine structurally related to interleukin 10.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eHuman IL-20 is synthesized as a 176 amino acid (aa) precursor with a 24 aa signal sequence and a 152 aa mature segment. IL-20 production has been found in skin\u003c\/span\u003e\u003cspan\u003e,\u003c\/span\u003e\u003cspan\u003e trachea, and other tissues. In particular, \u003c\/span\u003e\u003cspan\u003ei\u003c\/span\u003e\u003cspan\u003et is produced by activated keratinocytes and monocytes\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003cspan\u003e It has been shown that \u003c\/span\u003e\u003cspan\u003eIL\u003c\/span\u003e\u003cspan\u003e-20 transduces its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. It may be involved in epidermal function and psoriasis. It also regulates the proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. Also, \u003c\/span\u003e\u003cspan\u003ei\u003c\/span\u003e\u003cspan\u003et is reported to induce the proliferation of multipotential hematopoietic progenitor cells, direct the differentiation and expansion of keratinocytes, and promote the release of proinflammatory mediators in keratinocytes and other IL-20 receptor expressing cells.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct Properties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eCytokine Zcyto10\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eQ9NYY1\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003e50604\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived Human IL-20, \u003c\/span\u003e\u003cspan\u003eLeu25\u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003eGlu176, with an N-terminal Met\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately \u003c\/span\u003e\u003cspan\u003e17\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003cspan\u003e6\u003c\/span\u003e\u003cspan\u003e kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eMLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e5\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eThe ED50 as determined by a cell proliferation assay using human IL-20Rα and human IL-20Rβ co-transfected murine BaF3 pro-B cells is less than 0.5 ng\/m\u003c\/span\u003e\u003cspan\u003eL\u003c\/span\u003e\u003cspan\u003e, corresponding to a specific activity of \u0026gt; 2.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e6\u003c\/span\u003e\u003c\/sup\u003e\u003csup\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003eIU\/mg.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eFully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1.0 \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.2, with trehalose.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213666246974,"sku":"90119ES10","price":170.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213666279742,"sku":"90119ES60","price":760.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213666312510,"sku":"90119ES76","price":1905.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_2b1cef61-8a6d-4763-b261-af72de40fc26.jpg?v=1708077153"},{"product_id":"90118","title":"Recombinant Human Interleukin-19 (Human IL-19) _ 90118ES","description":"\u003cp\u003e\u003cspan\u003eThe molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the regulation of epidermal functions and inflammation. The expression of IL19 in biopsies of patients with active ulcerative colitis was increased compared with patients with quiescent ulcerative colitis and that colitis was attenuated in IL-19-deficient mice. The disruption of the epithelial barrier with dextran sodium sulfate leads to increased IL-19 expression. Attenuated colitis in IL-19-deficient animals was associated with reduced numbers of IL-6-producing macrophages in the inflamed colonic lamina propria. Microbial-driven expression of IL-19 by intestinal macrophages may contribute to the pathogenesis of inflammatory bowel disease.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eMelanoma Differentiation-associated Protein-like Protein, NG.1\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q9UHD0\" target=\"_blank\"\u003eQ9UHD0\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/29949\" target=\"_blank\"\u003e29949\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived human IL-19 protein, leu25-Ala177.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 17.9 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLRRCLISTDM HHIEESFQEI KRAIQAKDTF PNVTILSTLE TLQIIKPLDV CCVTKNLLAF YVDRVFKDHQ EPNPKILRKI SSIANSFLYM QKTLRQCQEQ RQCHCRQEAT NATRVIHDNY DQLEVHAAAI KSLGELDVFL AWINKNHEVM SSA\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e5\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eFully biologically active when compared to standard. The ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by a cell proliferation assay using human IL-20Rα and human IL-20Rβ co-transfected murine BaF3 pro-B cells is less than 1.5 ng\/ml, corresponding to a specific activity of \u0026gt; 6.7 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e5\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1.0 \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 100 mM HAC to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213666148670,"sku":"90118ES10","price":170.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213666181438,"sku":"90118ES60","price":760.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213666214206,"sku":"90118ES76","price":1905.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_f9b8d6bf-5254-417d-9541-00dc967b5cd5.jpg?v=1708077155"},{"product_id":"90117","title":"Recombinant Human Interleukin-17F (Human IL-17F) _ 90117ES","description":"\u003cp\u003e\u003cspan\u003eThe Interleukin 17F\u003c\/span\u003e\u003cspan\u003e (IL-17) family proteins, comprising six members (IL-17, IL-17B through IL-17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. With the exception of IL-17B, which exists as a noncovalently linked dimer, all IL-17 family members are disulfide-linked dimers. IL-17 family proteins are proinflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. Two receptors (IL17 R, and IL-17B R), which are activated by IL-17 family members, have been identified. In addition, at least three additional orphan type I transmembrane receptors with homology to IL-17 R, including IL-17 RL (IL-17 RC), IL-17 RD, and IL17 RE, have also been reported. Human IL-17B cDNA encodes a 180 aa protein with a putative 20 aa signal peptide. Human and mouse IL-17B share 88% amino acid sequence identity. Among IL-17 family members, IL-17B is most closely related to IL-17D, sharing 27% aa sequence homology. IL-17B is expressed highly in spinal cord, and at lower levels in brain, kidney, lung, small intestine, prostate, testes, pancreas, adrenal gland and trachea . Expression of IL-17B has also been detected in chondrocytes in articular cartilage. IL-17B binds the IL-17B receptor but not IL-17 R and exhibits bioactivities distinct from those of IL-17 .\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eML-1, IL-24\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q96PD4\" target=\"_blank\"\u003eQ96PD4\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/112744\" target=\"_blank\"\u003e112744\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived human IL-17F protein, Arg31-Gln163, with an N-terminal Met.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 30.1 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eMRKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 95% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eFully biologically active when compared to standard. The ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by inducing IL-6 secretion of murine NIH\/3T3 cells is less than 20 ng\/ml, corresponding to a specific activity of \u0026gt; 5.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e4 \u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003eIU\/mg.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1.0 \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 6 mM HCl to a concentration of 0.1\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003emg\/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"5 ug","offer_id":53213666050366,"sku":"90117ES08","price":115.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213666083134,"sku":"90117ES60","price":1125.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213666115902,"sku":"90117ES76","price":2920.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_87acaae7-d23f-4602-8962-25bd62c55868.jpg?v=1708077157"},{"product_id":"90116","title":"Recombinant Human Interleukin-17B (Human IL-17B) _ 90116ES","description":"\u003cp\u003e\u003cspan\u003eThe Interleukin 17B\u003c\/span\u003e\u003cspan\u003e (IL-17) family proteins, comprising six members (IL-17, IL-17B through IL-17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus (1, 2). With the exception of IL-17B, which exists as a noncovalently linked dimer, all IL-17 family members are disulfide-linked dimers (3). IL-17 family proteins are proinflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions (1, 2). Two receptors (IL17 R, and IL-17B R), which are activated by IL-17 family members, have been identified. In addition, at least three additional orphan type I transmembrane receptors with homology to IL-17 R, including IL-17 RL (IL-17 RC), IL-17 RD, and IL17 RE, have also been reported (14). Human IL-17B cDNA encodes a 180 aa protein with a putative 20 aa signal peptide (5, 6). Human and mouse IL-17B share 88% amino acid sequence identity. Among IL-17 family members, IL-17B is most closely related to IL-17D, sharing 27% aa sequence homology. IL-17B is expressed highly in spinal cord, and at lower levels in brain, kidney, lung, small intestine, prostate, testes, pancreas, adrenal gland and trachea (57). Expression of IL-17B has also been detected in chondrocytes in articular cartilage (2). IL-17B binds the IL-17B receptor but not IL-17 R and exhibits bioactivities distinct from those of IL-17 (5, 6).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd width=\"124\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"526\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eIL-17\u003c\/span\u003e\u003cspan\u003eB\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"124\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"526\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q9UHF5\" target=\"_blank\"\u003eQ9UHF5\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"124\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"526\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/27190\" target=\"_blank\"\u003e27190\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"124\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"526\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived human IL-17B protein, Gln21-Phe180, with an N-terminal Met.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"124\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"526\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 36.5 kDa, a non-disulfide-linked homodimer of two 161 amino acid polypeptide chains.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"124\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"526\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eMQPRSPKSKR KGQGRPGPLA PGPHQVPLDL VSRMKPYARM EEYERNIEEM VAQLRNSSEL AQRKCEVNLQ LWMSNKRSLS PWGYSINHDP SRIPVDLPEA RCLCLGCVNP FTMQEDRSMV SVPVFSQVPV RRRLCPPPPR TGPCRQRAVM ETIAVGCTCI F\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"124\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"526\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"124\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"526\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"124\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"526\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e5\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"124\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"526\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eFully biologically active when compared to standard. The ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by inducing IL-8 secretion of human HepG2 cells is less than 1.0 μg\/ml, corresponding to a specific activity of \u0026gt; 1000 IU\/mg.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"124\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"526\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; \u003c\/span\u003e\u003cspan\u003e0.1\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"124\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"526\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4, with 0.1% Tween-20 and 3% Trehalose.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"124\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"526\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"5 ug","offer_id":53213665952062,"sku":"90116ES08","price":115.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213665984830,"sku":"90116ES60","price":1125.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213666017598,"sku":"90116ES76","price":2920.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_5898b8dc-1d48-4fba-b7a4-7b1e5e2024e7.jpg?v=1708077160"},{"product_id":"90115","title":"Recombinant Human IL-17 Protein _ 90115ES","description":"\u003cdiv class=\"Section0\"\u003e\n\u003cdiv class=\"Section0\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eIL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival\/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. The IL-17 family of cytokines includes six members, IL-17\/IL-17A, IL-17B, IL-17C, IL-17D, IL-17E\/IL-25, and IL-17F, which are produced by multiple cell types. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2\/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis, and multiple sclerosis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eProduct \u003c\/b\u003e\u003cb\u003eProperties\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable class=\"Table\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eCytotoxic T-lymphocyte-associated antigen 8, CLTA-8 , IL-17A\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAccession\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q16552\" target=\"_blank\"\u003eQ16552\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eGeneID\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3605\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eE.coli-derived human IL-17 protein,Gly24-Ala155.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eApproximately 31.0 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAA Sequence\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eGITIPRNPGC PNSEDKNFPR TVMVNLNIHN RNTNTNPKRS SDYYNRSTSP WNLHRNEDPE RYPSVIWEAK CRHLGCINAD GNVDYHMNSV PIQQEILVLR REPPHCPNSF RLEKILVSVG CTCVTPIVHH VA\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eTag\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePhysical Appearance\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 95% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eBiological Activity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eFully biologically active when compared to standard. The ED\u003csub\u003e50\u003c\/sub\u003e as determined by inducing IL-6 secretion of murine NIH\/3T3 cells is less than 7.5 ng\/ml, corresponding to a specific activity of \u0026gt; 1.3 × 10\u003csup\u003e5\u003c\/sup\u003e IU\/mg\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1\u003cspan face=\"Times New Roman, Times, serif\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 4 mM HCl to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eShipping and Storage\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -20\u003cspan face=\"Times New Roman, Times, serif\"\u003e℃\u003c\/span\u003e for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1 month, 2 to 8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -20 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eCaution\u003c\/b\u003e\u003cb\u003es\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1.Avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2.For your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3.For research use only.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Yeasen","offers":[{"title":"5 ug","offer_id":48768528253246,"sku":"90115ES08","price":115.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":48768528286014,"sku":"90115ES60","price":710.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":48768528318782,"sku":"90115ES76","price":1925.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_5aac8e8f-e6a2-4011-8f3e-5525c8918c83.jpg?v=1708077162"},{"product_id":"90114","title":"Recombinant Human Interleukin-16, 130aa (Human IL-16, 130aa) _ 90114ES","description":"\u003cp\u003e\u003cspan\u003eInterleukin 16, also named lymphocyte chemoattractant factor (LCF), was originally identified as a CD8+ T-cell-derived chemoattractant for CD4+ cells. The biologically active form of IL-16 was originally proposed to be a homotetramer of 14 kDa chains containing 130 amino acid residue subunits. The complete pro-IL-16 cDNA was subsequently cloned and shown to encode a 631 amino acid residue hydrophilic protein that lacked a signal peptide. The original 130 amino acid residue polypeptide is now believed to have been derived from the C terminus of the precursor. IL-16 precursor protein has been detected in the lysates of various cells including mitogen stimulated PBMCs. The biologically active and secreted natural IL-16 is assumed to be a proteolytic cleavage product of pro-IL-16 generated by proteases present in or on activated CD8+ cells. A likely cleavage site was proposed to be at aspartate residue 510. This would yield a 121 amino acid residue protein, smaller than the 130 aa residue protein first described. The expression of IL-16 precursor mRNA has been detected in various tissues including spleen, thymus, lymph nodes, peripheral leukocytes, bone marrow and cerebellum. The gene for IL-16 precursor has been localized to chromosome 15.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eInterleukin-16 isoform 2, Lymphocyte chemoattractant factor, LCF\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q14005\" target=\"_blank\"\u003eQ14005\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/3603\" target=\"_blank\"\u003e3603\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived human IL-16 protein,Met1203-Ser1332,with an N-terminal Met.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 13.4 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eMPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e5\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eFully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CD4+ T Lymphocytes is in a concentration range of 1.0-100 ng\/ml.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1.0 \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 µm filtered concentrated solution in 20 mM Tris, 150 mM NaCl, pH 7.0.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCaution\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003es\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213665853758,"sku":"90114ES10","price":170.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213665886526,"sku":"90114ES60","price":760.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213665919294,"sku":"90114ES76","price":1905.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_c005b03a-06e0-447c-b64a-5dcd886f46a9.jpg?v=1708077164"},{"product_id":"90113","title":"Recombinant Human IL-15 Protein _ 90113ES","description":"\u003cdiv class=\"Section0\"\u003e\n\u003cdiv class=\"Section0\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eHuman Interleukin-15 (IL-15) is a widely expressed 14 kDa cytokine that is plays an important role in many immunological diseases. It shares approximately 97% and 73% sequence identity with simian and murine IL-15, respectively. Both human and simian IL-15 are active on murine cells. IL-15 is secreted by mononuclear phagocytes (and some other cells), especially macrophages following infection by virus. IL-15 and IL-2 have similar biologic properties in vitro, consistent with their shared receptor (R) signaling components (IL-2\/15Rβγc). A role for IL-15 during autoimmune processes such as rheumatoid arthritis and malignancies such as adult T-cell leukemia suggest that dysregulation of IL-15 may result in deleterious effects for the host. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eProduct \u003c\/b\u003e\u003cb\u003eProperties\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable class=\"Table\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-15, IL-15, MGC9721\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAccession\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P40933\" target=\"_blank\"\u003eP40933\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eGeneID\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/3600\" target=\"_blank\"\u003e3600\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eE.coli-derived human IL-15 protein, Asn49-Ser162.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eApproximately 12.9 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAA Sequence\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNWVNVISDLK KIEDLIQSMH IDATLYTESD VHPSCKVTAM KCFLLELQVI SLESGDASIH DTVENLIILA NNSLSSNGNV TESGCKECEE LEEKNIKEFL QSFVHIVQMF INTS\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eTag\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePhysical Appearance\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 97% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eBiological Activity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe ED\u003csub\u003e50\u003c\/sub\u003e as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.5 ng\/mL, corresponding to a specific activity of \u0026gt; 2.0 × 10\u003csup\u003e6\u003c\/sup\u003e IU\/mg. Fully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1\u003cspan face=\"Times New Roman, Times, serif\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20\u003cspan face=\"Times New Roman, Times, serif\"\u003e℃\u003c\/span\u003e. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eShipping and Storage\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -20 ℃ for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1 month, 2 to 8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -20 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eCaution\u003c\/b\u003e\u003cb\u003es\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1.Avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2.For your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3.For research use only!\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":51559921221950,"sku":"90113ES10","price":170.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":48768528679230,"sku":"90113ES60","price":635.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":48768528711998,"sku":"90113ES76","price":1730.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_59208de6-b18b-46c5-8939-6de336e22503.jpg?v=1708077166"},{"product_id":"90110","title":"Recombinant Human Interleukin-11 (Human IL-11) _ 90110ES","description":"\u003cp\u003e\u003cspan\u003eInterleukin 11 (IL-11), a member of the IL-6 family of cytokines, exerts pleiotropic activities by stimulating hemopoiesis and thrombopoiesis, regulating macrophage differentiation, and conferring mucosal protection in the intestine. These effects are mediated by a multimeric complex comprising the ligand-binding IL-11R± and the ubiquitously expressed gp130R-subunit, which together, trigger intracellular signaling and engagement of Stat3. Mature human IL-11 shares 88%, 88%, and 96% aa sequence identity with mouse, rat and canine IL-11, respectively. IL-11 is a pleotropic cytokine produced by lung stromal cells in response to respiratory viruses, cytokines, and histamine. The functions of IL-11 are that it directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eAdipogenesis inhibitory factor, AGIF, IL-11, IL-11Oprelvekin, interleukin 11, interleukin-11, Oprelvekin\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P20809\" target=\"_blank\"\u003eP20809\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/3589\" target=\"_blank\"\u003e3589\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived Human IL-11, Pro22-Leu199\u003c\/span\u003e\u003cspan\u003e, with an N-terminal Met.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 19.1 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eMPGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 95\u003c\/span\u003e\u003cspan\u003e%\u003c\/span\u003e\u003cspan\u003e by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eThe ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by a cell proliferation assay using murine B9-11 cells is less than 1 ng\/m\u003c\/span\u003e\u003cspan\u003eL\u003c\/span\u003e\u003cspan\u003e, corresponding to a specific activity of \u0026gt; 1.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e6\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg. Fully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1μg of the protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"531\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1\u003c\/span\u003e\u003cspan\u003e%\u003c\/span\u003e\u003cspan\u003e BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20\u003c\/span\u003e\u003cspan\u003e℃\u003c\/span\u003e\u003cspan\u003e. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":51559921090878,"sku":"90110ES10","price":185.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":51559921123646,"sku":"90110ES60","price":1430.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":51559921156414,"sku":"90110ES76","price":3150.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_23f1d585-f8b8-4cdb-92e8-59f0013dff28.jpg?v=1708077169"},{"product_id":"90108","title":"Recombinant Human Interleukin-9 (Human IL-9) _ 90108ES","description":"\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eInterleukin 9, also known as IL-9, is a cytokine (cell signaling molecule) belonging to the group of interleukins. IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL-9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eProduct \u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eProperties\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable class=\"Table\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eSynonyms\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eCytokine P40, T-cell Growth Factor P40\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eAccession\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eP15248\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eGeneID\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e3578\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eSource\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eE.coli-derived human IL-1alpha protein, Gln19-Ile144.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eMolecular Weight\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eApproximately 14.1 kDa.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eAA Sequence\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eQGCPTLAGIL DINFLINKMQ EDPASKCHCS ANVTSCLCLG IPSDNCTRPC FSERLSQMTN TTMQTRYPLI FSRVKKSVEV LKNNKCPYFS CEQPCNQTTA GNALTFLKSL LEIFQKEKMR GMRGKI\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eTag\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eNo\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003ene\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003ePhysical Appearance\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003ePurity\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e5\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eBiological Activity\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eFully biologically active when compared to standard. The ED\u003c\/span\u003e\u003csub\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e as determined by a cell proliferation assay using human MO7e cells is less than 0.2 ng\/ml, corresponding to a specific activity of \u0026gt; 5.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e6\u003c\/span\u003e\u003c\/sup\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e IU\/mg.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eEndotoxin\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e\u0026lt; 1.0 \u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eEU\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003eper \u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e1\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eμg of \u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003ethe \u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eprotein \u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eby \u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003ethe \u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eLAL method.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eFormulation\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eReconstitution\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eShipping and Storage\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e-\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e20\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e℃ to -80℃\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003efor \u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e1\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003eyear.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eCaution\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003es\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003col\u003e\n\u003cli align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eFor research use only.\u003c\/span\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003col\u003e\u003c\/ol\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":51559920959806,"sku":"90108ES10","price":265.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":51559920992574,"sku":"90108ES60","price":1430.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":51559921025342,"sku":"90108ES76","price":3625.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_f8d983e6-1adb-4f1b-9361-6018f829d06f.jpg?v=1708077171"},{"product_id":"90107","title":"Recombinant Human IL-6 Protein _ 90107ES","description":"\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eIL-6 is similar to other interleukins in that it has a compact globular folding structure and is held in place by two disulfide bonds. The cysteine involved in forming these two disulfide bonds is highly conserved. IL-6, expressed by a variety of cells, regulates cell growth and differentiation in various tissues and is an important pro-inflammatory and immunomodulatory cytokine.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e \u003c\/span\u003e\u003cb\u003e\u003cspan\u003eProduct Properties\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable class=\"Table\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eSynonyms\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eInterleukin-6,BSF2,HSF,IFNB2\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eUniprot No.\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eP05231\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eSource\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eRecombinant Human IL-6 Protein is expressed from E.coli without tag\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e. \u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eIt contains Val30-Met212.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eMolecular Weight\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eThe protein has a predicted 20.8 kDa same as Tris-Bis PAGE result.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003ePurity\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e\u0026gt; 95% as determined by SDS-PAGE.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eBiological Activity\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eThe ED\u003c\/span\u003e\u003csub\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e as determined by a cell proliferation assay using human TF-1 cells is 0.\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e1\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e-0.\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e5\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003eng\/mL. \u003c\/span\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eEndotoxin\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e\u0026lt; 1 EU per 1μg of the protein by the LAL method.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eFormulation\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS. Normally 8% trehalose is added as protectant before lyophilization\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eReconstitution\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eCentrifuge the tube before opening. Reconstituting to a concentration more than 100 μg\/ml is recommended. Dissolve the lyophilized protein in distilled water.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eShipping and Storage\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eThe product\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003eshould\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003ebe stored at -25~\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e-\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e15℃\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003efor 1 year from date of receipt\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e2-7 days\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e, 2 ~8 °C under sterile conditions after reconstitution.\u003c\/span\u003e  \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e3\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e-6\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003emonths, -\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e8\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e5~\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e-\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e6\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e5℃ under sterile conditions after reconstitution.\u003c\/span\u003e  \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003cb\u003eCaution\u003c\/b\u003e\u003cb\u003es\u003c\/b\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e1.\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003ePlease operate with lab coats and disposable gloves\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e,\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003efor your\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003esaf\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003ee\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003ety\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e.\u003c\/span\u003e   \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e2.\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eThis product is for research use only.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cstrong\u003eDocuments:\u003c\/strong\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eSafety Data Sheet\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e90107-_MSDS_HB\u003c\/span\u003e\u003cspan\u003e2\u003c\/span\u003e\u003cspan\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003e60210\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e_EN.PDF\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eManuals\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/90107-Manual-Ver.EN20260226.docx?v=1772097256\"\u003e90107-Manual-Ver.EN20260226\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"5 ug","offer_id":51559920828734,"sku":"90107ES08","price":60.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":51559920861502,"sku":"90107ES60","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_80a5c95a-66a0-409b-a2fd-91d7e1cd426e.jpg?v=1708077173"},{"product_id":"90102","title":"Recombinant Human Interleukin-1 Receptor Antagonist Protein (Human IL-1RA) _ 90102ES","description":"\u003cp\u003e\u003cspan\u003eIL-1ra was originally isolated from the urine of patients with monocytic leukemia and has also been purified from adherent monocytes. The naturally occurring, fully glycosylated form has an apparent molecular weight of about 25,000 Daltons. The protein shows 26% amino acid homology to IL-1 beta and 19% homology to IL-1 alpha. It will compete with either factor for receptor binding, but does not interact with either one. Human IL-1ra will bind to both types of IL-1 receptor (I and II) on human cells, but reportedly will not block binding to the type II receptor on murine pre-B cell lines. The recombinant, non-glycosylated form of IL-1ra blocks binding of IL-1 to its receptor equally as well as the naturally-occurring, glycosylated form. The IL-1ra has been shown to block the inflammatory responses induced by IL-1 both in vitro and in vivo. Currently, pre-clinical and clinical studies are underway to test possible therapeutic applications for IL-1ra in the treatment of sepsis, rheumatoid arthritis and chronic myelogenous leukemia.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eIL-1RN, IRAP\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eP18510\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e3557\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived\u003c\/span\u003e\u003cspan\u003e Human IL-1RA\u003c\/span\u003e\u003cspan\u003e, Arg26-Glu177.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 26.2 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eRPSGRKSSKM QAFRIWDVNQ KTFYLRNNQL VAGYLQGPNV NLEEKIDVVP IEPHALFLGI HGGKMCLSCV KSGDETRLQL EAVNITDLSE NRKQDKRFAF IRSDSGPTTS FESAACPGWF LCTAMEADQP VSLTNMPDEG VMVTKFYFQE DE\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e6\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eThe ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by inhibiting IL-1α-dependent proliferation of murine D10S cells is less than 40 ng\/m\u003c\/span\u003e\u003cspan\u003eL\u003c\/span\u003e\u003cspan\u003e, corresponding to a specific activity of \u0026gt; 2.5 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e4\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg in the presence of 50 pg\/ml rHuIL-1α. Fully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; \u003c\/span\u003e\u003cspan\u003e1.0\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eEU \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein by \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"100 μg","offer_id":53252681269566,"sku":"90102ES60","price":285.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_8dfb9c94-b3bc-49f5-aef8-b535ba4d2595.jpg?v=1708077175"},{"product_id":"91214","title":"Recombinant Mouse Interferon-lambda3\/Interleukin-28B (Mouse IFN-¦Ë3\/IL-28B) _ 91214ES","description":"\u003cp\u003e\u003cspan\u003eIL-28B (also named interferon-lambda 3, IFN-lambda 3), IL-28A (IFN-lambda 2) and IL-29 (IFN-lambda 1) are type III interferons that are class II cytokine receptor ligands. They are distantly related to members of the IL-10 family and type I IFN family. Human IL-28B cDNA encodes a 200 amino acid (aa) protein with a 25 aa signal peptide and a 175 aa mature protein that lacks N-glycosylation sites. Mature human IL-28B shares 64% and 75% aa sequence identity with mouse and canine IL-28B, respectively, and is active across species. Human IL-28B shares 94% and 69% aa identity with human IL-28A and IL29, respectively. Type III interferons are widely expressed, but are mainly produced by antigen presenting cells in response to viruses and double-stranded RNA that interact with Toll-like receptors or RIG-1 family helicases. They signal through a widely expressed receptor that is a heterodimer of the IL-10 receptor beta (IL-10 R beta ) and IL-28 receptor alpha (IL-28 R alpha ; also called IFN-lambda R1). Interaction of either type I or type III IFNs with their receptors activates similar pathways, including JAK tyrosine kinase activation, STAT phosphorylation and formation of the IFN-stimulated regulatory factor 3 (ISGF-3) transcription factor complex. Both type I and III IFNs induce antiviral activity and upregulate MHC class I antigen expression. Cell lines responsive to type III IFNs are also responsive to type I IFNs, but in general, higher concentrations of type III IFNs are needed for similar in vitro responses. In vivo, however, type III IFNs enhance levels of IFN-gamma in serum, suggesting that the robust anti-viral activity of type III IFNs may stem in part from activation of the immune system. Anti-proliferative and antitumor activity in vivo has also been shown for type III IFNs.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct Properties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"125\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"524\"\u003e\n\u003cp\u003e\u003cspan\u003eInterleukin 28B；Interferon lambda-3；IFN-lambda-3；Interleukin-28B\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"125\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"524\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q8CGK6\" target=\"_blank\"\u003eQ8CGK6\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"125\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"524\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/338374\" target=\"_blank\"\u003e338374\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"125\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"524\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived mouse Interferon-lambda3\/Interleukin-28B protein, Asp20-Val193\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"125\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"524\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 19.6 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"125\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"524\"\u003e\n\u003cp\u003e\u003cspan\u003eDPVPRATRLP VEAKDCHIAQ FKSLSPKELQ AFKKAKGAIE KRLLEKDMRC SSHLISRAWD LKQLQVQERP KALQAEVALT LKVWENINDS ALTTILGQPL HTLSHIHSQL QTCTQLQATA EPKPPSRRLS RWLHRLQEAQ SKETPGCLED SVTSNLFQLL LRDLKCVASG DQCV\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"125\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"524\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"125\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"524\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"125\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"524\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 98 % by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"125\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"524\"\u003e\n\u003cp\u003e\u003cspan\u003eFully biologically active when compared to standard. The ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is less than 30 ng\/ml, corresponding to a specific activity of \u0026gt; 3.3 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e4\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"125\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"524\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1.0 \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"125\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"524\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"125\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"524\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCaution\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003es\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"5 ug","offer_id":53213656514878,"sku":"91214ES08","price":115.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213656547646,"sku":"91214ES60","price":1125.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213656580414,"sku":"91214ES76","price":2920.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_af1e9f2c-c472-4745-b24b-441679aadd76.jpg?v=1708077418"},{"product_id":"91213","title":"Recombinant Mouse Interferon-lambda2\/Interleukin-28A (Mouse IFN-¦Ë2\/IL-28A) _ 91213ES","description":"\u003cp\u003e\u003cspan\u003eIL28A (Interferon-lambda 2; IFN-lambda 2), IL-28B\/IFN-lambda 3, and IL-29\/IFN-lambda 1 are type III interferons which are distantly related to IL-10 family and type I IFN family cytokines. Mature human IL-28A is an approximately 22-25 kDa protein that shares 66% amino acid (aa) sequence identity with mouse and rat IL-28A and shows cross-species activity. It shares 96% and 70% aa sequence identity with human IL-28B and IL-29, respectively. Type III interferons are upregulated in response to viral infection, and they act predominantly on epithelial cells through a receptor complex that contains IL-10 R beta and IL-28 R alpha \/IFN-gamma R1. Type III IFNs function as anti-viral molecules and induce the upregulation of MHC class I antigen. IL-28A promotes the Th1 polarization of dendritic cells in the airway (e.g. production of IL-12 p70 and IFN-gamma ) and inhibits Th2 and Th17 mediated inflammation. In the liver, however, the IL-28A induced Th1 cytokine response contributes to inflammation in T cell mediated hepatitis. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses in vivo. In contrast, it is up-regulated in invasive bladder cancer where it promotes tumor cell migration.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct Properties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd width=\"125\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"524\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eInterleukin 28A；Interferon lambda-2；Interleukin-28A；IFN-lambda-2\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"125\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"524\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q4VK74\" target=\"_blank\"\u003eQ4VK74\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"125\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"524\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e330496\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"125\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"524\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived Mouse IFN-λ2\/IL-28A, Asp20-Val193\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"125\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"524\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 19.7 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"125\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"524\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eDPVPRATRLP VEAKDCHIAQ FKSLSPKELQ AFKKAKDAIE KRLLEKDMRC SSHLISRAWD LKQLQVQERP KALQAEVALT LKVWENMTDS ALATILGQPL HTLSHIHSQL QTCTQLQATA EPKPPSRRLS RWLHRLQEAQ SKETPGCLED SVTSNLFRLL TRDLKCVASG DQCV\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"125\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"524\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"125\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"524\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"125\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"524\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 95 % by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"125\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"524\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eFully biologically active when compared to standard. The ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is less than 3 ng\/ml, corresponding to a specific activity of \u0026gt; 3.3 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e5\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"125\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"524\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; \u003c\/span\u003e\u003cspan\u003e0.1\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eEU\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein \u003c\/span\u003e\u003cspan\u003eby \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"125\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"524\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4, with 5 % trehalose.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"125\" valign=\"center\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"524\" valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCaution\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003es\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. Avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. For your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. For research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"5 ug","offer_id":53213656416574,"sku":"91213ES08","price":115.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213656449342,"sku":"91213ES60","price":1125.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213656482110,"sku":"91213ES76","price":2920.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_27b3cbbb-063f-4c4f-9abb-40c6e95fc142.jpg?v=1708077421"},{"product_id":"90193","title":"Recombinant Mouse IL-12 Protein _ 90193ES","description":"\u003cp align=\"justify\"\u003e\u003cspan\u003eInterleukin-12 (IL-12), also known as NKSF, TCMF, CLMF and TSF, is a heterodimeric cytokine composed of p35 and p40 subunits. It is produced by monocytes, macrophages, B cells and dendritic cells in response to bacterial lipopolysaccharides and intracellular pathogens. IL-12 signals throughtheIL-12 receptor complex, which is comprised of IL-12 Rβ1 and IL-12 Rβ2. IL-12 induces the proliferation and activation of hematopoietic stem cells, natural killer cells and T- cells. It is indispensible during the development of Th1 cells, leading to the production of IFN-gamma and IL-2.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eProduct Properties\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable class=\"Table\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eIL-12a ; IL-12b ; IL-12p35 ; IL-12p40 ; IL12p40 ; IL12a ; p35 ; p40 ;IL12\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAccession\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003ep35: P43431   p40: P43432\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eCHO-derived Mouse IL-12 protein, IL-12 p35 (Arg23-Ser215) \u0026amp; IL-12 p40 (Met23-Ser335).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e27~29 kDa (p35), 45~50 kDa (p40), on SDS-PAGE under reducing conditions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eTag\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 95% by SDS-PAGE.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eBiological Activity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eED\u003csub\u003e50\u003c\/sub\u003e \u0026lt; 0.15 ng\/ml, measured in a cell proliferation assay using 2D6 cells.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt; 0.2 EU per 1\u003cspan face=\"Times New Roman, Times, serif\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized after extensive dialysis against PBS.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eIt is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH\u003csub\u003e2\u003c\/sub\u003eO or PBS up to 100 μg\/ml. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eShipping and Storage\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -80\u003cspan face=\"Times New Roman, Times, serif\"\u003e℃\u003c\/span\u003e for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1 week, 2 to 8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -20 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eCaution\u003c\/b\u003e\u003cb\u003es\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1.Avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2.For your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3.For research use only.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213655957822,"sku":"90193ES10","price":270.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53213655990590,"sku":"90193ES50","price":1165.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_83ec2ddc-a8a7-4e42-95f3-8cf1c83af7bf.jpg?v=1708077451"},{"product_id":"90192","title":"Recombinant Mouse IL-18 Protein, His Tag _ 90192ES","description":"\u003cp\u003eInterleukin-18 (IL-18) is an effective pro-inflammatory cytokine that induces the production of interferon-gamma by Th1 cells, NK cells, and activated macrophages, especially in the presence of IL-12. IL-18 also plays a role in developmental regulation. The product is characterized by high activity, high purity, and low endotoxin levels. It undergoes validation and testing for biological activity, endotoxin levels, and SDS-PAGE to ensure consistency between batches. The product is provided without a carrier and is suitable for research and production of cell culture, ELISA, or immunoblotting standards.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Properties:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAliases:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eInterleukin 18; IL-18\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUniprot No.:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eP70380\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression Range and System:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eE.coli-derived Mouse IL-18 protein, Asn36-Ser192 with a His tag at the C-terminus.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eApproximately 18 kDa.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAppearance:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e\u0026gt; 98% as determined by SDS-PAGE\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eActivity:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eMeasure by its ability to induce IFN gamma secretion in KG-1 cells. The ED50 for this effect is 0.5 μg\/mL\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEndotoxin:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e\u0026lt; 0.1 EU per 1μg of the protein by the LAL method.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eFrom a solution containing 1×PBS, pH 8.0, lyophilized protein.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eUsage:\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eReconstitute the lyophilized powder with sterile water, with a concentration not less than 100 μg\/mL, and let it stand for at least 20 minutes to fully dissolve.\u003c\/li\u003e\n\u003cli\u003eThe reconstituted solution can be further diluted and aliquoted, with a shelf life of 1 month at 2-8℃, and 3 months at -20℃; avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n\u003cli\u003eWhen further diluting and aliquoting the reconstituted solution, add a certain amount of carrier protein (0.1% BSA, 10% FBS, or 5% HSA). For serum-free experiments, it can be replaced with a 5% trehalose solution as a carrier.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cstrong\u003eTransportation and Storage:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eShipped on ice. Store at -20℃ with a shelf life of one year.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNotes:\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eFor your safety and health, wear lab coats and disposable gloves during operation.\u003c\/li\u003e\n\u003cli\u003eThis product is for research purposes only!\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003col\u003e\u003c\/ol\u003e","brand":"Yeasen","offers":[{"title":"5 ug","offer_id":53213655826750,"sku":"90192ES08","price":125.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53213655859518,"sku":"90192ES20","price":315.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213655892286,"sku":"90192ES60","price":985.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213655925054,"sku":"90192ES76","price":2840.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_3b05ae5a-3488-4f86-87df-461a64c0247a.jpg?v=1708077454"},{"product_id":"90162","title":"Recombinant Mouse Interleukin-36 gamma, 152aa (Mouse IL-36¦Ã, 152aa) _ 90162ES","description":"\u003cp\u003e\u003cspan\u003eIL-36 gamma [previously called IL-1F9, IL-1 epsilon (epsilon), and IL-1H1] is a member of the IL-1 family which includes IL-1 beta, IL-1 alpha, IL-1ra, IL-18, IL-36 Ra (IL-1F5), IL-36 alpha (IL-1F6), IL-36 beta (IL-1F8), IL-37 (IL-1F7) and IL-1F10. All family members show a 12 beta-strand, beta-trefoil configuration, and are believed to have arisen from a common ancestral gene. Mouse IL-36 gamma is an 18-22 kDa, 164 amino acid (aa) intracellular and secreted protein that contains no signal sequence, no prosegment and no potential N-linked glycosylation sites. Mouse IL-36 gamma (aa 13-164) shares 58%, 84%, 64% and 60% aa sequence identity with human, rat, equine and bovine IL-36 gamma, respectively, and 23-57% aa sequence identity with other family members. A 193 aa mouse isoform with a 29 aa N-terminal extension has been reported. Highest levels of IL-36 gamma are produced by Langerhans cells, keratinocytes, and stomach Chief cells and parietal cells; these cells contribute to first-line defense against pathogens in the skin, lungs and digestive tract. Its expression is induced by LPS treatment of monocytes, and by IL-alpha \/ beta, IL-17 or TNF-alpha treatment of keratinocytes and bronchial epithelia. Skin IL-36 gamma expression is increased in contact hypersensitivity and psoriasis. It is elevated in inflammatory disorders of the lung (such as asthma) and viral infections. Lung IL-36 gamma and other IL-36 proteins contribute to neutrophil influx. The receptor for IL-36 gamma is a combination of IL-1 Rrp2, mainly found in epithelia and keratinocytes, and the widely expressed IL-1 RAcP. IL-36 alpha, beta and gamma all activate NF-kappa B and MAPK pathways in an IL-1 Rrp2 dependent manner, and IL-36 gamma induces production of inflammatory cytokines and chemokines such as CXCL8\/IL-8. Full-length recombinant IL-36 proteins appear less active than their endogenous counterparts, but trimming of the N-termini enhances their activity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e IL1F9; IL-1F9; IL1H1; IL-1H1\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eQ8R460\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eMm.249379.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived\u003c\/span\u003e\u003cspan\u003e Mouse IL-36γ, 152aa,\u003c\/span\u003e\u003cspan\u003e Gly13-Ser164.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 17.3 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eGRETPDFGEV FDLDQQVWIF RNQALVTVPR SHRVTPVSVT ILPCKYPESL EQDKGIAIYL GIQNPDKCLF CKEVNGHPTL LLKEEKILDL YHHPEPMKPF LFYHTRTGGT STFESVAFPG HYIASSKTGN PIFLTSKKGE YYNINFNLDI KS\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e7\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eThe ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by inducing IL-6 secretion in murine NIH\/3T3 cells is less than 10 ng\/m\u003c\/span\u003e\u003cspan\u003eL\u003c\/span\u003e\u003cspan\u003e, corresponding to a specific activity of \u0026gt; 1.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e5\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eFully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; \u003c\/span\u003e\u003cspan\u003e0.1\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eEU \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein by \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 µm filtered solution in 1 M MOPS, 10 mM NaAC, pH7.6, with 2 mM EDTA, 5% Trehalose, 0.02 % Tween-20.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213655761214,"sku":"90162ES10","price":265.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213655793982,"sku":"90162ES76","price":5055.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_1c1d92bd-77e4-4c79-a765-223c6722e20f.jpg?v=1708077457"},{"product_id":"90161","title":"Recombinant Mouse Interleukin-36 beta, 153aa (Mouse IL-36¦Â, 153aa) _ 90161ES","description":"\u003cp\u003e\u003cspan\u003eMouse interleukin-36 beta [IL-36 beta ; previously IL-1F8, FIL-1 eta(eta) and IL-1H2] is a member of the IL-1 family of proteins that includes IL-1 beta, IL-1 alpha, IL-1ra, IL-18, IL-36Ra\/IL-1F5, IL-36 alpha \/IL-1F6, IL-37\/IL-1F7, IL-36 gamma \/IL-1F9 and IL-1F10. All family members show a 12 beta-stranded beta-trefoil configuration, share up to 50% amino acid (aa) sequence identity, and are believed to have arisen from a common ancestral gene. Although two alternatively spliced transcript variants for human IL-36 beta \/IL-1F8 have been described, to date, only one mouse IL-36 beta \/IL-1F8 isoform is known. Mouse IL-36 beta \/IL-1F8 shares 61% and 74% aa identity with human IL-36 beta isoform 2 and rat IL-36 beta, respectively. IL-36 beta is agonistic, stimulating release of inflammatory mediators such as IL-6 and IL-8, and cytotoxic peptides such as beta-defensins 2 and 3 that aid in defense against microbial pathogens. The receptor for IL-36 proteins is IL-1 Rrp2, with IL-1 RAcP as a coreceptor. Antagonism of IL-36 proteins by IL-36Ra, which also binds IL-1 Rrp2, has been shown by some investigators. Skin keratinocytes express highest levels of IL-36 proteins and their receptors, followed by epithelia in the esophagus, trachea and bronchae. IL-36 beta expression is increased in psoriatic skin and may play a role in pathogenesis of psoriasis. IL-36 beta is also expressed in resting and activated monocytes and B cells, synovial fibroblasts, neurons and glia, and is detectable in plasma and body fluids. IL-36 beta, along with IL-36 alpha and IL-36 gamma, is up-regulated by IL-1 alpha and TNF- alpha in keratinocytes, and has been shown to activate NF- kappa B and MAPK signaling pathways in an IL-1 Rrp2-dependent manner. Full-length recombinant IL-36 proteins appear less active than their endogenous counterparts, but trimming of the N-termini enhances their activity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eFIL1 eta, IL-1 eta, IL-1F8, IL-1H2\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eQ9D6Z6\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e69677\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eMouse IL-36β, 153aa\u003c\/span\u003e\u003cspan\u003e, \u003c\/span\u003e\u003cspan\u003eSer31\u003c\/span\u003e\u003cspan\u003e-Lys183.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately \u003c\/span\u003e\u003cspan\u003e17.4\u003c\/span\u003e\u003cspan\u003e kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSSQSPRNYRV HDSQQMVWVL TGNTLTAVPA SNNVKPVILS LIACRDTEFQ DVKKGNLVFL GIKNRNLCFC CVEMEGKPTL QLKEVDIMNL YKERKAQKAF LFYHGIEGST SVFQSVLYPG WFIATSSIER QTIILTHQRG KLVNTNFYIE SEK\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e7\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eThe ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by inducing IL-6 secretion in murine NIH\/3T3 cells is less than 10 ng\/m\u003c\/span\u003e\u003cspan\u003eL\u003c\/span\u003e\u003cspan\u003e, corresponding to a specific activity of \u0026gt; 1.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e5\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eFully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; \u003c\/span\u003e\u003cspan\u003e1.0\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eEU \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein by \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4, 5% trehalose.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213654778174,"sku":"90161ES10","price":265.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213654810942,"sku":"90161ES76","price":5055.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_939d5215-7ecd-4ea1-a6c0-a0567c6198d9.jpg?v=1708077460"},{"product_id":"90158","title":"Recombinant Mouse Interleukin-36 alpha, 160aa (Mouse IL-36¦Á,160aa) _ 90158ES","description":"\u003cp\u003e\u003cspan\u003eIL36 alpha, previously called IL1F6 and FIL1 epsilon  (family of IL1 member epsilon), is a member of the IL1 family which includes IL1 beta, IL1 alpha, IL1ra, IL18, and novel family members IL36 Ra (IL1F5), IL36 beta (IL1F8), IL36 gamma (IL1F9), IL37 (IL1F7) and IL1F10. All family members show a 12 beta strand, beta trefoil configuration, and are believed to have arisen from a common ancestral gene. IL36 alpha is an 18 kDa, 160 amino acid (aa) intracellular and secreted protein that contains no signal sequence, no prosegment and no potential Nlinked glycosylation sites. It can be externalized nonspecifically in response to LPS and ATPinduced activation of the P2X7 receptor. Fulllength recombinant IL36 alpha is less active than endogenous IL36 alpha, but trimming of the Ntermini enhances its activity. Mouse IL36 alpha shares 83% aa sequence identity with rat IL36 alpha, 5460% with human, rabbit, equine and bovine IL36 alpha, and 2757% aa sequence identity with other novel IL1 family members. IL36 alpha is mainly found in skin and lymphoid tissues, but also in fetal brain, trachea, stomach and intestine. It is expressed by monocytes, B and T cells. The receptor for IL36 alpha is a combination of IL1 Rrp2 (also called IL1 RL2 or IL1 R6), mainly found in epithelia and keratinocytes, and the widely expressed IL1 RAcP. IL36 alpha, beta and gamma all activate NF kappa B and MAPK pathways in an IL1 Rrp2 dependent manner, and induce production of inflammatory cytokines and chemokines such as CXCL8\/IL8. IL36 alpha and other family members are overexpressed in psoriatic skin lesions, and transgenic overexpression of IL36 alpha in skin keratinocytes produces epidermal hyperplasia. IL36 alpha is present in kidney tubule epithelia; it is highly overexpressed in tubulointerstitial lesions in mouse models of chronic glomerulonephritis, lupus nephritis and diabetic nephritis. IL36 alpha is induced by inflammation in adipose tissueresident alternately activated (M2) macrophages, and reduces adipocyte differentiation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eFIL1 epsilon, IL-1 epsilon, IL-1F6, IL-1H1\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eQ9JLA2\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e54448\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived\u003c\/span\u003e\u003cspan\u003e Mouse IL-36α,160aa\u003c\/span\u003e\u003cspan\u003e, Met1-His160, with an N-terminal Met.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 18.0 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eMNKEKELRAA SPSLRHVQDL SSRVWILQNN ILTAVPRKEQ TVPVTITLLP CQYLDTLETN RGDPTYMGVQ RPMSCLFCTK DGEQPVLQLG EGNIMEMYNK KEPVKASLFY HKKSGTTSTF ESAAFPGWFI AVCSKGSCPL ILTQELGEIF ITDFEMIVVH\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e5\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eThe specific activity determined by its ability in a functional ELISA. Immobilized rMuIL-36α at 1 µg\/mL can bind recombinant murine IL-1 Rrp2 with a range of 0.15-5 µg\/mL. Fully biologically active when compared to standard. \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1μg of the protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4, 5 % trehalose.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213654712638,"sku":"90158ES10","price":265.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213654745406,"sku":"90158ES76","price":5055.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_554b4282-19be-40de-b1be-9f6a3eb3aff4.jpg?v=1708077462"},{"product_id":"90157","title":"Recombinant Mouse Interleukin-33 (Mouse IL-33) _ 90157ES","description":"\u003cp\u003e\u003cspan\u003eIL-33, also known as NF-HEV and DVS 27, is a 17.5\u003c\/span\u003e\u003cspan\u003e kDa proinflammatory protein that may also regulate gene transcription. DVS 27 was identifed as a gene that is upregulated in vasospastic cerebral arteries. NF-HEV was described as a nuclear factor that is preferentially expressed in the endothelial cells of high endothelial venules relative to endothelial cells from other tissues. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines. DVS 27, NF-HEV, and IL-33 share 100% amino acid sequence identity. IL-33 is constitutively expressed in smooth muscle and airway epithelia. It is upregulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1 alpha or IL1 beta stimulation. Similar to IL-1, IL-33 can be cleaved in vitro by caspase1, generating an Nterminal fragment that is slightly shorter than the Cterminal fragment. The Nterminal portion of full length IL-33 contains a predicted bipartite nuclear localization sequence and a homeodomain-like helix-turn-helix DNA binding domain. By immunofluorescence, full length IL-33 localizes to the nucleus in HUVECs and transfectants. The Cterminal fragment, corresponding to mature IL-33, binds and triggers signaling through mast cell IL1 R4\/ST2L, a longtime orphan receptor involved in the augmentation of Th2 cell responses. A ternary signaling complex is formed by the subsequent association of IL-33 and ST2L with IL1 RAcP. Stimulation of Th2 polarized lymphocytes with mature IL-33 in vitro induces IL-5 and IL-13 secretion. In vivo administration of mature IL-33 promotes increased production of IL-5, IL-13, IgE, and IgA, as well as splenomegaly and inflammatory infiltration of mucosal tissues. Full length and mature mouse IL-33 share approximately 55% and 90% aa sequence identity with human and rat IL-33, respectively. Mouse IL-33 shares less than 25% aa sequence identity with other IL-1 family proteins.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct Properties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eIL-1F11, NF-HEV\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eQ8BVZ5\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e77125\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived\u003c\/span\u003e\u003cspan\u003e Mouse IL-33\u003c\/span\u003e\u003cspan\u003e, Ser109-Ile266.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 17.5 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSKI\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e8\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eThe ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by a cell proliferation assay using murine D10S cells is less than 0.5 ng\/m\u003c\/span\u003e\u003cspan\u003eL\u003c\/span\u003e\u003cspan\u003e, corresponding to a specific activity of \u0026gt; 2.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e6\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eFully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; \u003c\/span\u003e\u003cspan\u003e1.0\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eEU \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein by \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 µm filtered solution in PBS, and 1 mM EDTA.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213654647102,"sku":"90157ES10","price":170.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213654679870,"sku":"90157ES76","price":1890.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_bf89c5e8-86a3-4fd6-8faf-f1bf963c1f6e.jpg?v=1708077465"},{"product_id":"90155","title":"Recombinant Mouse Interleukin-22 (Mouse IL-22) _ 90155ES","description":"\u003cp\u003e\u003cspan\u003eInterleukin-22 (IL-22), also known as IL-10-related T cell-derived inducible factor (IL-TIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid (aa) residue protein with a putative 33 aa signal peptide that is cleaved to generate a 147 aa mature protein that shares approximately 79% and 22% aa sequence identity with human IL-22 and IL-10, respectively. The mouse IL-22 gene is localized to chromosome 10. Although it exists as a single copy gene in many mouse strains, the IL-22 gene is duplicated in some mouse strains including C57B1\/6, FVB and 129. The two mouse genes designated IL-TIF alpha and IL-TIF beta, share greater than 98% sequence homology in their coding region. IL-22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10R beta (previously known as CRF2-4), belonging to the class II cytokine receptor family.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct Properties\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr class=\"firstRow\"\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eIL-TIF, IL-TIF alpha, IL-22a\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eQ9JJY9\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e50929\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eE.coli-derived\u003c\/span\u003e\u003cspan\u003e Mouse IL-22\u003c\/span\u003e\u003cspan\u003e, Leu34-Val179.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eApproximately 16.6 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLPVNTRCKLE VSNFQQPYIV NRTFMLAKEA SLADNNTDVR LIGEKLFRGV SAKDQCYLMK QVLNFTLEDV LLPQSDRFQP YMQEVVPFLT KLSNQLSSCH ISGDDQNIQK NVRRLKETVK KLGESGEIKA IGELDLLFMS LRNACV\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eNo\u003c\/span\u003e\u003cspan\u003ene\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026gt; 9\u003c\/span\u003e\u003cspan\u003e6\u003c\/span\u003e\u003cspan\u003e% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eThe ED\u003c\/span\u003e\u003csub\u003e\u003cspan\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan\u003e as determined by inducing IL-10 secretion of human COLO 205 cells is less than 0.2 ng\/m\u003c\/span\u003e\u003cspan\u003eL\u003c\/span\u003e\u003cspan\u003e, corresponding to a specific activity of \u0026gt; 5.0 × 10\u003c\/span\u003e\u003csup\u003e\u003cspan\u003e6\u003c\/span\u003e\u003c\/sup\u003e\u003cspan\u003e IU\/mg. Fully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003e\u0026lt; \u003c\/span\u003e\u003cspan\u003e1.0\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eEU \u003c\/span\u003e\u003cspan\u003eper \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003eμg of \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eprotein by \u003c\/span\u003e\u003cspan\u003ethe \u003c\/span\u003e\u003cspan\u003eLAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in 1 × PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"124\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"526\"\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eShipping and Storage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at \u003c\/span\u003e\u003cspan\u003e-\u003c\/span\u003e\u003cspan\u003e20\u003c\/span\u003e\u003cspan\u003e℃ to -80℃\u003c\/span\u003e\u003cspan\u003e for \u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213654548798,"sku":"90155ES10","price":170.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213654581566,"sku":"90155ES60","price":775.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213654614334,"sku":"90155ES76","price":1935.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_a68b63b2-09fa-4c7d-8e8f-dac6b69c681f.jpg?v=1708077468"}],"url":"https:\/\/www.yeasenbio.com\/fa\/collections\/interleukins.oembed?page=4","provider":"Yeasen - Leading Innovation in Molecular Enzymes and Reagents","version":"1.0","type":"link"}