{"product_id":"90906","title":"Rekombinant human vækstreguleret protein-gamma\/CXCL3 (Human Gro-y\/CXCL3) _ 90906ES","description":"\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHuman GRO alfa, GRO beta (MIP-2 alpha) og GRO gamma (MIP-2 beta) er produkter af tre forskellige, ikke-alleliske humane gener. GRO beta og GRO gamma deler henholdsvis 90 % og 86 % aminosyresekvenshomologi med GRO alfa. Alle tre humane GRO'er er medlemmer af alfa (CXC) underfamilien af ​​kemokiner og menes at være homologer af murine KC og MIP-2.\u003c\/span\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eDe tre GRO-cDNA'er koder for 107 aminosyre-precursorproteiner, hvorfra de N-terminale 34 aminosyrerester spaltes for at generere de modne GRO'er. Der er ingen potentielle N-bundne glycosyleringssteder i aminosyresekvenserne. GRO-ekspression kan induceres af serum eller PDGF og\/eller af en række forskellige inflammatoriske mediatorer, såsom IL-1 og TNF, i monocytter, fibroblaster, melanocytter og epitelceller. I visse tumorcellelinjer udtrykkes GRO konstitutivt.\u003c\/span\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eI lighed med andre alfa-kemokiner er de tre GRO-proteiner potente neutrofile tiltrækningsmidler og aktivatorer. Derudover er disse kemokiner også aktive over for basofiler. Alle tre GRO'er kan binde med høj affinitet til IL-8-receptoren type B.\u003c\/span\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e  \u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eProdukt \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eEgenskaber\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003cdiv class=\"tableResponsive\" data-mce-fragment=\"1\"\u003e  \u003ctable width=\"100%\" cellspacing=\"0\" data-mce-fragment=\"1\"\u003e  \u003ctbody data-mce-fragment=\"1\"\u003e  \u003ctr class=\"firstRow\" data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eSynonymer\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eGRO-gamma, MIP2-beta\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eTiltrædelse\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eP19876\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eGeneID\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e2921\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eKilde\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eE.coli-afledt menneske \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003eGRO-y\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e,Ala35-Asn107.\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eMolekylvægt\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eCirka 7,9 kDa\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAA-sekvens\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eTag\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eIngen\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eFysisk udseende\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eSterilt filtreret hvidt frysetørret (frysetørret) pulver.\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eRenhed\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u0026gt; 97 % ved SDS-PAGE og HPLC analyser.\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eBiologisk aktivitet\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eFuldt biologisk aktiv sammenlignet med standard. Den biologiske aktivitet bestemt ved en kemotakse-bioassay under anvendelse af humane CXCR2-transficerede humane 293-celler er i et koncentrationsområde på 10-100 ng\/m\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003eL\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e.\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eEndotoksin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u0026lt;  1 EU pr. 1μg af proteinet ved LAL-metoden.\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eFormulering\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eLyofiliseret fra en 0,2 µm filtreret koncentreret opløsning i 20 mM PB, pH 7,4, 50 mM NaCl.\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003ctr data-mce-fragment=\"1\"\u003e  \u003ctd width=\"124\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eRekonstitution\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003ctd width=\"526\" valign=\"center\" data-mce-fragment=\"1\"\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eVi anbefaler, at dette hætteglas kort centrifugeres inden åbning for at bringe indholdet til bunden. Rekonstituer i sterilt destilleret vand eller vandig buffer indeholdende 0,1 % BSA til en koncentration på 0,1-1,0 mg\/ml.Stamopløsninger bør fordeles i arbejdsalikvoter og opbevares ved ≤ -20°C. Yderligere fortyndinger bør foretages i passende bufferopløsninger.\u003c\/span\u003e\u003c\/p\u003e  \u003c\/td\u003e  \u003c\/tr\u003e  \u003c\/tbody\u003e  \u003c\/table\u003e  \u003c\/div\u003e  \u003cp data-mce-fragment=\"1\"\u003e  \u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eForsendelse og opbevaring\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eProdukterne sendes med ispose og kan opbevares kl \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e-\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e20\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e℃ til -80 ℃\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e for \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e1\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e år.\u003c\/span\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAnbefal at alikvotere proteinet i mindre mængder, når det bruges første gang\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e  \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003eog undgå gentagen frysning-\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003etø \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003ecyklusser.\u003c\/span\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e  \u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eForsigtig\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e1. Undgå gentagen fryse-tø-cyklus.\u003c\/span\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e2. For din sikkerhed og sundhed skal du bære laboratoriefrakker og engangshandsker til betjening.\u003c\/span\u003e\u003c\/p\u003e  \u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e3. Kun til forskningsbrug.\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"100 ug","offer_id":53213668114750,"sku":"90906ES60","price":565.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53213668147518,"sku":"90906ES76","price":1410.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_ae34779f-37e4-4793-819f-f925c62d95a5.jpg?v=1708077079","url":"https:\/\/www.yeasenbio.com\/da\/products\/90906","provider":"Yeasen - Leading Innovation in Molecular Enzymes and Reagents","version":"1.0","type":"link"}