{"title":"Organoid-Related Cytokines","description":null,"products":[{"product_id":"92276","title":"Recombinant Human Wnt-3a Protein _ 92276ES","description":"\u003cdiv class=\"Section0\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eWnt3a, one of Wnt family members, plays key roles in regulating pleiotropic cellular functions, including self-renewal, proliferation, differentiation, and motility. The Wnt family comprises 19 human proteins, including Wnt1, Wnt2, Wnt2b (Wnt13), Wnt3, Wnt3a, Wnt4, Wnt5a, Wnt5b, Wnt6, Wnt7a, Wnt7b, Wnt8a, Wnt8b, Wnt9a (Wnt14), Wnt9b (Wnt14b), Wnt10a, Wnt10b, Wnt11, and Wnt16. These genes encode secreted glycoproteins that are rich in cysteine. Wnts can combine with cell membrane receptors that play a critical role in autocrine regulation and\/or participate in paracrine modification by binding to adjacent cell membrane receptors. The signal transduction pathway mediated by Wnt genes is called the Wnt signaling pathway. Accumulating evidence has suggested that Wnt3a promotes or suppresses tumor progression via the canonical Wnt signaling pathway depending on cancer type. In addition, the roles of Wnt3a signaling can be inhibited by multiple proteins or chemicals. Human Wnt-3a shares 96% aa identity with mouse mouse, bovine and canine Wnt-3a, and 89%, 86% and 84% aa identity with chicken, Xenopus and zebrafish Wnt-3a, respectively. It also shares 87% aa identity with Wnt3. During embryonic development, Wnt-3a is necessary for proper development of the hippocampus, anterior-posterior patterning, somite development, and tailbud formation. Wnt-3a also promotes self-renewal of hematopoietic stem cells, neural stem cells, and embryonic stem cells.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003cb\u003e\u003cspan\u003eProduct Properties\u003c\/span\u003e\u003c\/b\u003e \u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable class=\"Table\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 20.0694%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 77.357%;\"\u003e\n\u003cp\u003eWnt Surrogate;Wnt Surrogate-Fc Fusion Protein;\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 20.0694%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 77.357%;\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 20.0694%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eGeneID\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 77.357%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e89780\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 20.0694%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 77.357%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eHEK293 cells-derived Human wnt-3a, Ser19-Lys352.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 20.0694%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 77.357%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eApproximately 63.3 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 20.0694%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAA Sequence\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 77.357%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSY PIWWSLAVGP QYSSLGSQPI LCASIPGLVP KQLRFCRNYV EIMPSVAEGI KIGIQECQHQ FRGRRWNCTT VHDSLAIFGP VLDKATRESA FVHAIASAGV AFAVTRSCAE GTAAICGCSS RHQGSPGKGW KWGGCSEDIE FGGMVSREFA DARENRPDAR SAMNRHNNEA GRQAIASHMH LKCKCHGLSG SCEVKTCWWS QPDFRAIGDF LKDKYDSASE MVVEKHRESR GWVETLRPRY TYFKVPTERD LVYYEASPNF CEPNPETGSF GTRDRTCNVS SHGIDGCDLL CCGRGHNARA ERRREKCRCV FHWCCYVSCQ ECTRVYDVHT CK\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 20.0694%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eTag\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 77.357%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eFc\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 20.0694%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 77.357%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 75% as determined by SDS-PAGE.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 20.0694%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eActivity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 77.357%;\"\u003e\n\u003cp\u003eMeasured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The ED50 for this effect is 25 ng\/mL.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 20.0694%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 77.357%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt; 0.1 EU per 1\u003cspan style=\"font-family: 'Times New Roman', Times, serif;\" face=\"Times New Roman, Times, serif\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" style=\"width: 20.0694%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" style=\"width: 77.357%;\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from a 0.2 µm filtered concentrated solution in PBS.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable class=\"Table\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cb\u003eShipping and Storage\u003c\/b\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -80 ℃ for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003cspan\u003e\u003cb\u003eCaution\u003c\/b\u003e\u003cb\u003es\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003cspan\u003e1.Avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2.For your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3.For research use only!\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53209583845694,"sku":"92276ES10","price":115.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53209583878462,"sku":"92276ES60","price":790.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":46859525292350,"sku":"92276ES80","price":4075.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/5_8baf88e3-9a4a-4a24-a793-d2b56ac20ab9.jpg?v=1767072272"},{"product_id":"92278","title":"Recombinant Human RSPO1 Protein _ 92278ES","description":"\u003cdiv class=\"Section0\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eR-Spondin 1 (RSPO1, Roof plate-specific Spondin 1), also known as cysteine-rich and single thrombospondin domain containing protein 3, is a 27 kDa secreted protein that shares ~40% aa identity with three other R-Spondin family members . All R-Spondins regulate Wnt\/ beta-Catenin signaling but have distinct expression patterns. In humans, rare disruptions of the R-Spondin 1 gene are associated with tendencies for XX sex reversal (phenotypic male) or hermaphroditism, indicating a role for R-Spondin 1 in gender- Injection of recombinant R-Spondin 1 in mice causes activation of beta-catenin and proliferation of intestinal crypt epithelial cells, and ameliorates experimental colitis. Interest in R-Spondin 1 as a cell culture supplement has grown with the expansion of the organoid field. R-Spondin 1 is widely used in organoid cell culture workflows as a vital component that promotes both growth and survival of 3D organoids .\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eProduct Properties\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctable border=\"0\" cellspacing=\"2\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"137\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"377\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eR-Spondin 1 \u003cspan style=\"font-family: 宋体;\"\u003e；\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003eRoof Plate-specific Spondin 1\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"137\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"377\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eQ2MKA7\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"137\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"377\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eCHO Stable Cells-derived human RSPO1 protein, Met1-Ala 263.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"137\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"377\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eApproximately 26.8 kDa. As a result of glycosylation, the apparent molecular mass of it is approximately 40 and 31 kDa in SDS-PAGE under reducing conditions.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"137\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"377\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eMRLGLCVVAL VLSWTHLTIS SRGIKGKRQR RISAEGSQAC AKGCELCSEV NGCLKCSPKL FILLERNDIR QVGVCLPSCP PGYFDARNPD MNKCIKCKIE HCEACFSHNF CTKCKEGLYL HKGRCYPACP EGSSAANGTM ECSSPAQCEM SEWSPWGPCS KKQQLCGFRR GSEERTRRVL HAPVGDHAAC SDTKETRRCT VRRVPCPEGQ KRRKGGQGRR ENANRNLARK ESKEAGAGSR RRKGQQQQQQ QGTVGPLTSA GPA    \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"137\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"377\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"137\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"377\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"137\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"377\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u0026gt; 95% by SDS-PAGE.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"137\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"377\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eMeasured by its ability to induce activation of ßcatenin response in a Topflash Luciferase assay using HEK293T human embryonic kidney cells. The ED50 for this effect is typically 20-120 ng\/mL in the presence of 5 ng\/mL recombinant mouse wnt3a.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"137\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"377\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1μg of the protein by the LAL method.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"137\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"377\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"137\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"377\" valign=\"center\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eShipping and Storage\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -20\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003e℃\u003c\/span\u003e for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92278.jpg?v=1742224086\"\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eCaution\u003c\/b\u003e\u003cb\u003es\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003e1.\u003c\/span\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003e2.\u003c\/span\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Times New Roman, Times, serif\" style=\"font-family: 'Times New Roman', Times, serif;\"\u003e3.\u003c\/span\u003eFor research use only.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53217794687294,"sku":"92278ES10","price":70.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":46859526046014,"sku":"92278ES60","price":415.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":46859526078782,"sku":"92278ES80","price":1995.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92278.jpg?v=1742224086"},{"product_id":"92528","title":"Recombinant Human Noggin Protein,His Tag _ 92528ES","description":"\u003cp\u003e\u003cstrong\u003e\u003cb\u003eDescription\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNoggin is a bone morphogenetic protein (BMP) antagonist expressed in Spemann's organizer. It inhibits TGF-β family ligands and preventing them from binding to their corresponding receptors.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eProduct information\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"203\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"793\"\u003e\n\u003cp\u003eNOG, SYM1, symphalangism 1 (proximal), synostoses (multiple) syndrome 1, SYNS1\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"203\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eUniprot No.\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"793\"\u003e\n\u003cp\u003eQ13253\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"203\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"793\"\u003e\n\u003cp\u003eHEK293 cells -derived human Noggin protein, Gln28-Cys232, with a His tag at the C-terminal\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"203\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"793\"\u003e\n\u003cp\u003eThe protein migrates as 30 KDa under reducing (R) condition (SDS-PAGE) .\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"203\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003e Activity\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"793\"\u003e\n\u003cp\u003eMeasured by its ability to bind BMP2 with Elisa method .\u003c\/p\u003e\n\u003cp\u003eOptimal concentrations should be determined by each laboratory for each application\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"203\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"793\"\u003e\n\u003cp\u003e\u0026gt; 95% as determined by SDS-PAGE.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"203\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"793\"\u003e\n\u003cp\u003e\u0026lt;1.0 EU per 1μg of the protein by the LAL method.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"203\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"793\"\u003e\n\u003cp\u003eLyophilized from a 0.2 μm filtered solution in PBS.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"203\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"793\"\u003e\n\u003cp\u003eIt is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH\u003csub\u003e2\u003c\/sub\u003eO or PBS up to 100 μg\/ml.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eStorage\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe product should be stored at -85~-65℃ for 1 year from date of receipt.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eNotes\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1.Please operate with lab coats and disposable gloves,for your safety.\u003c\/p\u003e\n\u003cp\u003e2.This product is for research use only.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e\u003cspan\u003eDocuments\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eManuals:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92528-Manual-Ver.EN20260414.pdf?v=1776218989\"\u003e92528_Manual_HB20260414.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53213675094334,"sku":"92528ES10","price":80.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53213675127102,"sku":"92528ES60","price":350.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":46859537416510,"sku":"92528ES80","price":1890.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/5_c6c3e5b1-4bd8-4eb3-a442-973b73856f17.png?v=1700906060"},{"product_id":"92703","title":"Recombinant Mouse EGF Protein _ 92703ES","description":"\u003cdiv class=\"Section0\"\u003e\n\u003cdiv class=\"Section0\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eEpidermal growth factor (EGF) is a small, potent growth factor capable of inducing cell proliferation, differentiation, and survival. EGF is the founding member of the EGF family that also includes TGF-alpha, amphiregulin (AR), betacellulin (BTC), epiregulin (EPR), heparinbinding EGFlike growth factor (HBEGF), epigen, and the neuregulins (NRG)-1 through -6. Members of The EGF family are characterized by a shared structural motif, the EGFlike domain, which contains three intramolecular disulfide bonds that are formed by six similarly spaced, conserved cysteine residues. These disulfide bonds are essential for proper protein conformation and receptor binding. All EGF family members are synthesized as type I transmembrane precursor proteins that may contain several EGF domains in the extracellular region. The mature proteins are released from the cell surface by regulated proteolysis. The full length EGF protein is 1207 amino acids (aa) (EGF precursor) containing nine EGF domains and nine LDLR class B repeats. However, the mature protein is much smaller, only 53 aa, and is generated by proteolytic cleavage of the EGF domain proximal to the transmembrane region. EGF is well conserved across mammals with mature human EGF 70% identical to mature mouse and rat EGF. Physiologically, EGF is found in various body fluids, including blood, milk, urine, saliva, seminal fluid, pancreatic juice, cerebrospinal fluid, and amniotic fluid. EGF is a high affinity ligand of the EGF receptor (ErbB). Four ErbB (HER) family receptor tyrosine kinases including EGFR\/ErbB1, ErbB2, ErbB3 and ErbB4, mediate responses to EGF family members. EGF binding induces dimerization of the EGF receptor resulting in activation of the protein tyrosine kinase signaling pathway. These receptors undergo a complex pattern of ligand-induced homo- or hetero-dimerization to transduce EGF family signals. EGF binds ErbB1 and depending on the context, induces the formation of homodimers or heterodimers containing ErbB2.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eProduct \u003c\/b\u003e\u003cb\u003eProperties\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable class=\"Table\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eUrogastrone, URG\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eP01132\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eGeneID\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e13645\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eE.coli-derived Mouse EGF, Asn977-Arg1029.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eApproximately 6.0 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eAA Sequence\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt; 97% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe ED\u003csub\u003e50\u003c\/sub\u003e as determined by a cell proliferation assay using murine Balb\/c 3T3 cells is less than 0.1 ng\/mL, corresponding to a specific activity of \u0026gt; 1.0 × 10\u003csup\u003e7\u003c\/sup\u003e IU\/mg. Fully biologically active when compared to standard. \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable class=\"Table\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1μg of the protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20\u003cspan face=\"Times New Roman, Times, serif\"\u003e℃\u003c\/span\u003e. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eS\u003c\/b\u003e\u003cb\u003ehipping\u003c\/b\u003e\u003cb\u003e and S\u003c\/b\u003e\u003cb\u003etorage\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -20 ℃ for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1 month, 2 to 8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -20 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eCaution\u003c\/b\u003e\u003cb\u003es\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Times New Roman, Times, serif\"\u003e1.\u003c\/span\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Times New Roman, Times, serif\"\u003e2.\u003c\/span\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Times New Roman, Times, serif\"\u003e3.\u003c\/span\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Yeasen","offers":[{"title":"100 ug","offer_id":51559920730430,"sku":"92703ES60","price":115.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":51559920763198,"sku":"92703ES76","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_842b752b-e8d0-4b38-b815-5e32c20befea.jpg?v=1708077293"},{"product_id":"92282","title":"Recombinant Human\/Mouse Wnt-5a Protein, His Tag _ 92282ES","description":"\u003ch3 class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eSpecifications\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003ctable class=\"MsoTableGrid\" border=\"1\" cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"311\" valign=\"top\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eCat.N\u003c\/span\u003e\u003cspan\u003eo\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"651\" valign=\"top\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e92282ES10\u003c\/span\u003e\u003cspan\u003e \/ \u003c\/span\u003e\u003cspan\u003e92282ES60\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\/ \u003c\/span\u003e\u003cspan\u003e92282ES76\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"311\" valign=\"top\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eSize\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"651\" valign=\"top\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e10 μg\u003c\/span\u003e\u003cspan\u003e \/ \u003c\/span\u003e\u003cspan\u003e100 μg\u003c\/span\u003e\u003cspan\u003e \/ \u003c\/span\u003e\u003cspan\u003e500 μg\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3 class=\"p\"\u003e\n\u003cb\u003e\u003cspan\u003ePerformance parameters\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003ctable class=\"MsoTableGrid\" border=\"1\" cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"240\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"744\" valign=\"top\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eWingless-type MMTV Integration Site Family, Member 5a; wingless-type MMTV integration site\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003efamily, member 5A; Wnt5a\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"240\" valign=\"top\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"744\" valign=\"top\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eHEK293 Cells, Gln38-Lys380 with a His tag at the C-terminal\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"240\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eUniProt\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"744\" valign=\"top\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eP41221\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"240\" valign=\"top\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"744\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003eThe protein has a predicted MW of 40kDa. The protein migrates as 60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"240\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"744\" valign=\"top\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u0026gt; 90% by SDS-PAGE.\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"240\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"744\" valign=\"top\"\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1μg of the protein by the LAL method.\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"240\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eF\u003c\/span\u003e\u003cspan\u003eormulation\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"744\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eLyophilized from 0.22 μm filtered solution in PBS, pH7.4, 5% trehalose and 0.01 % Tween 80\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ewere added as protectant before lyophilization\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"240\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eReconstitution\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"744\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eReconstitute at 100 μg\/mL in sterile PBS containing at least 0.1% human or bovine serum\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ealbumin.\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3 class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eStorage\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eThe product should be stored at -85~-65℃ for 1 year. \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eNotes\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e1. \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan\u003ePlease operate with lab coats and disposable gloves,for your safety.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e2. \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan\u003eThis product is for research use only.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 class=\"p\"\u003e\n\u003cb\u003e\u003cspan\u003eProduct Data\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eElectrophoresis (SDS-PAGE)\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/1_7fba3214-ee96-4949-ba73-3ce1a32f1a7a_1024x1024.png?v=1757037174\" alt=\"Figure 1. Human wnt5a Protein on SDS PAGE under reduced\u0026amp;nbsp;condition.  The purity is greater than\u0026amp;nbsp;90%.\" style=\"margin-right: 219px; margin-bottom: 16px; margin-left: 219px; float: none;\"\u003e\u003c\/div\u003e\n\u003cp align=\"center\"\u003eFigure 1. Human wnt5a Protein on SDS PAGE under reduced condition.\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" align=\"center\"\u003eThe purity is greater than 90%.\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cspan\u003eDocuments:\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003cp\u003eSafety Data Sheet\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92282-MSDS-HB250930.pdf?v=1759224144\"\u003e92282_MSDS_HB250822_EN.PDF\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eManuals\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92282ES-Manual-Ver.EN20250905.pdf?v=1757036833\"\u003e92282_Manual_Ver.EN20250905.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":53209551896894,"sku":"92282ES10","price":115.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53209551929662,"sku":"92282ES60","price":710.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":53209551962430,"sku":"92282ES76","price":2485.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_4dd46555-ac09-40c4-a98c-56183bcf2280.jpg?v=1708077312"},{"product_id":"92277","title":"Recombinant Mouse RSPO1 Protein, His Tag _ 92277ES","description":"\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eR-Spondin 1 (RSPO1, Roof plate-specific Spondin 1), also known as cysteine-rich and single thrombospondin domain containing protein 3. Interest in R-Spondin 1 as a cell culture supplement has grown with the expansion of the organoid field. R-Spondin 1 is widely used in organoid cell culture workflows as a vital component that promotes both growth and survival of 3D organoids .\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb data-mce-fragment=\"1\"\u003eProduct Properties\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable class=\"Table\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eSynonyms\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eR-Spondin 1;Roof Plate-specific Spondin 1\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e；\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eCristin3; R-spondin-1\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eSource\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eExpressed in E. coli.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eMolecular Weight\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eApproximately 20.9kDa, a single non-glycosylated polypeptide chain containing 189 amino acid\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eAccession\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"https:\/\/www.uniprot.org\/uniprotkb\/Q9Z132\/entry\" target=\"_blank\"\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eQ9Z132\u003c\/span\u003e\u003c\/a\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e: \u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eSer21-Gly209\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eBiological Activity\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eFully biologically active when compared to standard. Measured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The typical ED\u003c\/span\u003e\u003csub\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e50\u003c\/span\u003e\u003c\/sub\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e is 50-200 ng\/mL in the presence of 5ng\/mL recombinant mouse Wnt-3a.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003ePurity\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e\u0026gt; 96% by SDS-PAGE.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eEndotoxin\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e＜\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e0.01EU\/μg protein as determined by LAL method.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eFormulation\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eLyophilized from a 0.2\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003em\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003em filtered solution in \u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e20mM PB, 150mM NaCl,\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003epH 7.4.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eReconstitution\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eBefore use this product, please read the direction below carefully.\u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e1.This vial must be briefly centrifuged prior to opening to bring the contents to the bottom.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e2.Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg\/ml.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eStock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb data-mce-fragment=\"1\"\u003eShipping and Storage\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eThe product\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003eshould\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003ebe stored at -25~\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e-\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e15℃\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003efor 1 year from date of receipt\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e1 month,\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003e2 ~8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e3 months, -25~\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e-\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e15℃ under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eRecommend to aliquot the protein into smaller quantities when first used\u003c\/span\u003e \u003cspan face=\"Helvetica Neue宋体\"\u003eand avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb data-mce-fragment=\"1\"\u003eCaution\u003c\/b\u003e\u003cb data-mce-fragment=\"1\"\u003es\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e1.\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003ePlease operate with lab coats and disposable gloves\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e,\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003efor your saf\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003ee\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003ety\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003e2.\u003c\/span\u003e\u003cspan face=\"Helvetica Neue宋体\"\u003eThis product is for research use only.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"1 mg","offer_id":53252692541758,"sku":"92277ES80","price":2135.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_7b55f7a7-d6d0-42f7-b43f-4ef090f8acea.jpg?v=1708077518"},{"product_id":"92262","title":"Recombinant Mouse Noggin Protein _ 92262ES","description":"\u003cdiv class=\"Section0\"\u003e\n\u003cdiv class=\"Section0\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNoggin is a bone morphogenetic protein (BMP) antagonist expressed in Spemann's organizer.  It inhibits TGF-β family ligands and preventing them from binding to their corresponding receptors. Noggin was originally found as a BMP-4 antagonist, and then has been shown to modulate the activities of other BMPs (BMP-2, 7, 13 and 14). Noggin is very highly conserved among vertebrates, such that mature human Noggin shares 99%, 99%, 98%, 97% and 89% aa sequence identity with mouse, rat, bovine, equine and chicken Noggin, respectively. Secreted noggin protein regulates bone morphogenetic protein activity during development. The Role of the BMP Signaling Antagonist Noggin in the Development of Prostate Cancer Osteolytic Bone Metastasis. Lack of expression of the BMP antagonist noggin by osteoinductive, carcinoma-derived cell lines is a determinant of the osteoblast response induced by their bone metastases. In contrast, osteolytic, carcinoma-derived cell lines express noggin constitutively.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eProduct \u003c\/b\u003e\u003cb\u003eProperties\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable class=\"Table\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNOG, SYM1, symphalangism 1 (proximal), synostoses (multiple) syndrome 1, SYNS1, SYNS1A\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAccession\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P97466\" target=\"_blank\"\u003eP97466\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eGeneID\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/18121\" target=\"_blank\"\u003e18121\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eSource\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eE.coli-derived human Noggin protein, Gln28-Cys232, with an N-terminal Met.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eApproximately 46.4 kDa.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eAA Sequence\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eMQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eTag\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eNone\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePhysical Appearance\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026gt;95% by SDS-PAGE and HPLC analyses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eBiological Activity\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe ED\u003csub\u003e50\u003c\/sub\u003e as determined by inhibiting BMP-4-induced alkaline phosphatase production of murine ATDC5 cells is less than 2 ng\/mL, corresponding to a specific activity of \u0026gt; 5.0 × 10\u003csup\u003e5\u003c\/sup\u003e IU\/mg in the presence of 5 ng\/mL BMP-4. Fully biologically active when compared to standard.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eEndotoxin\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u0026lt; 1.0 EU per 1\u003cspan face=\"Times New Roman, Times, serif\"\u003eμg of \u003c\/span\u003ethe protein by the LAL method.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eFormulation\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eLyophilized from a 0.2 μm filtered concentrated solution in 30% acetonitrile, 0.1% TFA.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eReconstitution\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\"\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 10 mM HAc to a concentration less than 0.25 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20\u003cspan face=\"Times New Roman, Times, serif\"\u003e℃\u003c\/span\u003e. Further dilutions should be made in appropriate buffered solutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eS\u003c\/b\u003e\u003cb\u003ehipping\u003c\/b\u003e\u003cb\u003e and S\u003c\/b\u003e\u003cb\u003etorage\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eThe products are shipped with ice pack and can be stored at -20 ℃ for 1 year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e1 month, 2 to 8 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e3 months, -20 °C under sterile conditions after reconstitution.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003eRecommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e \u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cb\u003eCaution\u003c\/b\u003e\u003cb\u003es\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Times New Roman, Times, serif\"\u003e1.\u003c\/span\u003eAvoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Times New Roman, Times, serif\"\u003e2.\u003c\/span\u003eFor your safety and health, please wear lab coats and disposable gloves for operation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"justify\"\u003e\u003cspan\u003e\u003cspan face=\"Times New Roman, Times, serif\"\u003e3.\u003c\/span\u003eFor research use only!\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Yeasen","offers":[{"title":"5 ug","offer_id":53252691951934,"sku":"92262ES08","price":95.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/products\/20220513162505336_a2ad885b-7bc5-4b37-ad73-7af927bb9598.jpg?v=1708077526"},{"product_id":"92294","title":"Recombinant Human Wnt-3a protein (Liquid) _ 92294ES","description":"\u003ctable border=\"0\" cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"497\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003eProduct Name\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"163\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003eCat#\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"164\" valign=\"center\"\u003e\n\u003cp class=\"p\" align=\"justify\"\u003e\u003cspan\u003eSize\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"497\" valign=\"center\" rowspan=\"4\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e  Recombinant Human Wnt-3a\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eProtein\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"163\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e92294ES10\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"164\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e10 μg\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"163\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e92294ES60\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"164\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e100 μg\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"163\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e92294ES76\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"164\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e500 μg\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"163\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e92294ES80\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"164\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e1 mg\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eWnt-3a belongs to the Wnt family of signaling proteins, which plays an important role in maintaining the integrity of embryonic and adult tissues.The Wnt family is highly conserved and cysteine-rich.The Wnt signaling pathway can be divided into classical and non-classical pathways, and is involved in the β-catenin-mediated classical signaling pathway including Wnt1, Wnt2, Wnt2b, Wnt3, Wnt3a, Wnt7a, Wnt8, Wnt8b and Wnt10a. Wnt3a, Wnt7a, Wnt8, Wnt8b and Wnt10a, the classical signaling pathway regulates stem cell pluripotent differentiation, organ development and regeneration.Wnt3a signals through the frizzled (FZD) family of receptors and the LRP5\/6 co-receptor to regulate gene expression and a variety of cellular behaviors.Wnt3a, as the most representative signaling protein of the Wnt family, has a wide distribution, and has a role in the regulation of potent cellular functions (including self-renewal, proliferation, and cell regeneration). As the most representative signaling protein of the Wnt family, it is widely distributed and plays a key role in the regulation of pleiotropic cellular functions, including self-renewal, proliferation, differentiation, and motility.Wnt3a is an important ecological niche component for maintaining the proliferation of Lgr5-positive stem cells in intestinal epithelial cells.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eCurrently, Wnt3a protein has been used in organoid cultures such as intestinal, gastric, pancreatic, hepatic, thyroid and ovarian cancers, etc. Its high activity, batch-to-batch stability and serum-free preparation are the keys to the success of organoid experiments. Wnt3a protein purified by NextSense is generally used in organoid culture at a working concentration of 30-100 ng\/mL, which is usually able to activate the Wnt signaling pathway and promote organoid development and cell function. The optimal concentration to use needs to be optimized and determined based on the specific experimental purpose, cell type and culture conditions. This product is supplied in liquid form and is characterized by high purity, high activity, low endotoxin and no animal-derived components, and has been validated in multiple organoid cultures.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eSpecification\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003ctable border=\"0\" cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"141\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"697\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eWnt Surrogate;Wnt Surrogate-Fc Fusion Protein;\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"141\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"697\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eHEK293\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"141\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"697\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e60-75 kDa\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"141\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"697\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e\u0026gt; 95% by SDA-PAGE.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"141\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"697\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e\u0026lt;0.1\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eEU\/μg\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"141\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"697\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eMeasured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The ED50 for this effect is 25 ng\/mL.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"141\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"697\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e1 mg\/mL recombinant protein in Sterile PBS (pH 7.4)\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"141\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eCompounding Methods\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"697\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eBrief centrifugation before opening is recommended to bring the contents to the bottom. Reconstitute to a concentration of 0.1-1.0 mg\/mL in sterile distilled water. The stock solution should be divided into aliquots and stored at \u003c\/span\u003e\u003cspan\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003e≤ \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e-20\u003c\/span\u003e\u003cspan\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003e°\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eC.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"141\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"697\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eLiquid\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"141\" valign=\"center\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003econcentration\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"697\" valign=\"top\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e1 mg\/mL\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eStorage\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e-85~-65℃ for storage, valid for 1 year after receipt.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eIt is recommended to aliquot the protein for the first use to avoid repeated freeze-thaw cycles. \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e1. Please operate with lab coats and disposable gloves,for your safety.   \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e2\u003c\/span\u003e\u003cspan\u003e. This product is for research use only.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eDigital\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eSDS-PAGE\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92294-1_e5fb59b5-8c40-4951-9c72-c900a8fc17c7_1024x1024.png?v=1740987418\" alt=\"Figure 1. Human wnt3a Protein on SDS PAGE under reduced condition.\u0026amp;nbsp;The purity is greater than 95%.\" style=\"margin-bottom: 16px; float: none;\"\u003e\u003c\/div\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\n\u003cp class=\"p\"\u003eFigure 1. Human wnt3a Protein on SDS PAGE under reduced condition. The purity is greater than 95%.\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eCell Based Assa\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cimg alt=\"Figure 2. Measured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The ED50 for this effect is25 ng\/mL\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92294-2_600x600.jpg?v=1740987421\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003eFigure 2. Measured by its ability to induce Topflash reporter \u003c\/span\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003eactivity in HEK293T human embryonic kidney cells. The ED50 for \u003c\/span\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003ethis effect is25 ng\/mL\u003c\/span\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eOrganoid Culture\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"Figure 3.Ovarian cancer-like organs cultured for 6 days\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92294-3_600x600.png?v=1740987129\"\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003eFigure 3.\u003c\/span\u003eOvarian cancer-like organs cultured for 6 days\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cimg style=\"float: none;\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92294-4.png?v=1740987133\" alt=\"Figure 4.Small intestinal organoids in mice cultured for 7 days\"\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003eFigure 4.\u003c\/span\u003eSmall intestinal organoids in mice cultured for 7 days\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cimg style=\"float: none;\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92294-5.png?v=1740987137\" alt=\"Figure 5.Pancreatic cancer-like organs cultured for 5 days\"\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003eFigure 5.\u003c\/span\u003ePancreatic cancer-like organs cultured for 5 days\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cspan\u003eDocuments:\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003cp\u003eSafety Data Sheet\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92294-MSDS-HB250930.pdf?v=1759224136\"\u003e92294_MSDS_HB250822_EN.PDF\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eManuals\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92294ES-Manual-Ver.EN20250905.pdf?v=1757036822\"\u003e92294_Manual_Ver.EN20250905.pdf\u003c\/a\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":51559919812926,"sku":"92294ES10","price":80.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":51559919845694,"sku":"92294ES60","price":430.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":51559919878462,"sku":"92294ES76","price":1175.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":51386110738750,"sku":"92294ES80","price":2355.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92294-1.jpg?v=1742223656"},{"product_id":"92291","title":"Recombinant Mouse Noggin Protein (HEK293) _ 92291ES","description":"\u003cp\u003e\u003cspan\u003eNoggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). It is very well conserved in vertebrates, so mature human Noggin has high homology to mouse, rat, bovine, equine, and chicken species.Noggin specifically binds and inhibits BMPs, which play an important role in early embryonic development, limb formation, and neurological development, as well as antagonizing BMPs, which affects normal development of the body's bone, cartilage, and joints.Noggin Noggin was originally identified as a BMP-4 antagonist and plays an important role in the proper formation of the head and other dorsal structures. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eTherefore, Noggin has a high affinity for certain BMPs such as BMP-4, a low affinity for BMP-7, and a high correlation with BMP-2, BMP-13 and BMP-14. During skeletal development, Noggin prevents chondrocyte proliferation, which in turn regulates normal joint formation.Noggin is used in the adult central nervous system and peripheral tissues (e.g., lungs) when human embryonic stem cells (hESCs) or neural stem cells are cultured under certain conditions.Addition of Noggin to antagonize BMP activity results in the proliferation of the stem cells, while keeping them in an undifferentiated state, or differentiating them into dopaminergic neurons. In Noggin-deficient mice, enhanced BMP activity causes a range of developmental abnormalities, including failure of neural tube formation, delayed hair follicle development, axial skeletal malformations, and arthropathy.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eThis recombinant mouse Noggin is high activity, high purity, low endotoxin and label free.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan class=\"15\"\u003e\u003cspan style=\"font-family: Inter SemiBold;\"\u003eSpecification\u003c\/span\u003e\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan class=\"15\"\u003e \u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan class=\"15\"\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003ctable cellspacing=\"0\" border=\"0\" class=\"MsoNormalTable\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"309\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"377\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eNoggin; NOG; SYM1; SYNS1\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"309\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"377\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eHEK293\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"309\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eSequence\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"377\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eLeu20-Cys232\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"309\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"377\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eP97466\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"309\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"377\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003ePredicted Moleucular weight: 23.1 kDa\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"309\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"377\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e\u0026lt; 0.01 EU\/μg by the LAL method.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"309\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"377\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e\u0026gt; 95%\u003cspan style=\"font-family: sans-serif;\"\u003e，\u003c\/span\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003edetermined by SDS-PAGE\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"309\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eBiological Activity\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"377\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eMeasured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The EC50 for this effect is 12-20 ng\/mL in the presence of 50 ng\/mL of Recombinant Human BMP-4.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"309\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"377\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eDissolved\u003c\/span\u003e\u003cspan\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003ein\u003c\/span\u003e\u003cspan\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003esterile\u003c\/span\u003e\u003cspan\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003ePBS\u003c\/span\u003e\u003cspan\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003ebuffer.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"309\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"377\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003eNot\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"309\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003ePhysical Appearance\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"377\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003eF\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eluids\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan class=\"15\"\u003e\u003cspan style=\"font-family: Inter SemiBold;\"\u003eStorage\u003c\/span\u003e\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan class=\"15\"\u003e \u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan class=\"15\"\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e-85~-65℃ storage, valid for 1 year after receipt.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eAvoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan class=\"15\"\u003e\u003cspan style=\"font-family: Inter SemiBold;\"\u003eCautions\u003c\/span\u003e\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan class=\"15\"\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e1. For your safety and health, please wear lab coat and disposable gloves.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e2. This product is for scientific research purposes only.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":51559917617470,"sku":"92291ES10","price":90.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":51559917650238,"sku":"92291ES60","price":555.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":51559917683006,"sku":"92291ES76","price":1665.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92623.jpg?v=1764210718"},{"product_id":"92295","title":"Recombinant Mouse R spondin 1\/RSPO1 Protein, His Tag (HEK293) _ 92295ES","description":"\u003cp class=\"p\"\u003e\u003cspan\u003eR-Spondin-1 (Rspo-1) belongs to the (Rspo) family of Wnt regulators. Currently, the family consists of four structurally related secreted ligands (Rspo 1-4), all of which contain a Frizzled-like structural domain and a platelet-responsive protein structural domain.Rspo-1 is expressed in certain regions of the developing central nervous system, as well as the adrenal glands, ovaries, testes, thyroid gland, and trachea.Rspo can interact with the Wnt\/\u003c\/span\u003e\u003cspan\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003eβ\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e-catenin signaling pathway in a manner that stimulates the Frizzled\/LRP6 receptor complex interaction. With the expanding field of organoids, R-Spondin 1 is widely used in organoid cell cultures as an essential component to promote growth and survival of 3D organoids..\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eSpecification\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003ctable cellspacing=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"215\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eSynonyms\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"528\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eR-spondin-1; RSPO1; CRISTIN3; FLJ40906; RP11-566C13.1; RSPO; R-Spondin1\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"215\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eSpecies\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"528\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eMouse\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"215\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eSource\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"528\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eHEK293\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"215\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eSequence\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"528\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eSer21-Gln265\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"215\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eAccession\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"528\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eQ9Z132\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"215\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eTag\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"528\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eC-His\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"215\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eMolecular Weight\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"528\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eThe protein has a predicted MW of 28.3 kDa. Due to glycosylation, the protein migrates to 45-48 kDa based on Bis-Tris PAGE result.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"215\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eEndotoxin\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"528\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e\u0026lt; 1 EU\/μg by the LAL method.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"215\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"528\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e\u0026gt; 95% as determined by Bis-Tris PAGE\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"215\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eActivity\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"528\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eELISA Data: Immobilized Mouse R spondin 1, His Tag at 5 μg\/ml (100 μl\/Well) on the plate. Dose response curve for Mouse RNF43, hFc Tag with the EC50 of 0.11\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003cspan style=\"font-family: Inter Medium;\"\u003eμg\/ml determined by ELISA.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003eCell Based Assay: Measured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The ED50 for this effect is 4 - 20 ng\/mL in\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003ethe presence of 5 ng\/mL recombinant Human Wnt3a .\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"215\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eFormulation\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"528\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eLyophilized from 0.22 μm filtered solution in 20\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003emM MES, 150\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003emM NaCl, 200\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003emM Arginine (pH 5.5). Normally 8% trehalose \/ 8% mannitol is added as protectant before lyophilization.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"center\" width=\"215\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eAppearance\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"center\" width=\"528\"\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eL\u003c\/span\u003e\u003cspan\u003eyophilized powder\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eStorage \u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e-25 ~ -15 ° C storage, 1 year expiration date after receipt. After re-solution, store at 2 ~8 °C, 7 days expiration date. After re-dissolving, store at -85~-65°C, 3 months expiration date.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eCompounding Methods\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003eCentrifuge before uncapping. It is recommended to reconstitute to a concentration of more than 100 μg\/ml. lyophilized proteins are dissolved in 20 mM MES, 150 mM NaCl, 200 mM Arginine (pH 5.5).\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan\u003eCautions\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e1. For your safety and health, please wear lab coat and disposable gloves.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\"\u003e\u003cspan\u003e2. This product is for scientific research purposes only.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 class=\"p\" style=\"text-align: left;\"\u003e\n\u003cstrong\u003eDocuments:\u003c\/strong\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003cp class=\"MsoNormal\" style=\"text-align: left;\"\u003e\u003cspan\u003eSafety Data Sheet\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p\" style=\"text-align: left;\"\u003e \u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"text-align: left;\"\u003e\u003cspan\u003eManuals\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92295-Manual-Ver.EN20260303.docx?v=1772519948\"\u003e92295-Manual-Ver.EN20260303\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"25 ug","offer_id":51559917453630,"sku":"92295ES25","price":270.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":51559917486398,"sku":"92295ES60","price":835.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":51559917519166,"sku":"92295ES76","price":2710.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92623.jpg?v=1764210718"},{"product_id":"92623","title":"Recombinant Human Noggin Protein _ 92623ES","description":"\u003cp\u003eNoggin is a secreted homodimeric glycoprotein. Secreted Noggin is affixed to the cell surface due to binding to heparin-containing proteoglycans and is an antagonist of bone morphogenetic proteins (BMPs). Noggin is very conserved in vertebrates, so mature human Noggin has high homology to mouse, rat, bovine, equine, and chicken species.Noggin is involved in common regulatory signaling pathways such as the Wnt signaling pathway, the BMP signaling pathway, and the Shh signaling pathway, etc. The Noggin gene has a feedback inhibitory mechanism for the BMP signaling pathway and a feedback activating mechanism for the Wnt signaling pathway. The inhibitor Noggin in the BMP signaling pathway mediates the inhibition of BMP expression to cause Shh signaling.\u003c\/p\u003e\n\u003cp\u003eNoggin is a secreted protein that binds to ligands of the TGF-α family and regulates their activity by inhibiting their access to signaling receptors.Noggin was initially identified as a BMP-4 antagonist and plays an important role in the proper formation of the head and other dorsal structures. As such, Noggin has a high affinity for certain BMPs such as BMP-4 and a lower affinity for BMP-7, in addition to a high correlation with BMP-2, BMP-13 and BMP-14. During skeletal development, Noggin prevents chondrocyte proliferation, which in turn regulates normal joint formation.Noggin is used in the adult central nervous system and peripheral tissues (e.g., lungs) when human embryonic stem cells (hESCs) or neural stem cells are cultured under certain conditions.Addition of Noggin to antagonize BMP activity results in the proliferation of the stem cells, while keeping them in an undifferentiated state, or differentiating them into dopaminergic neurons.              \u003c\/p\u003e\n\u003cp\u003eNoggin is one of the most classical growth factors in organoid culture, and its high activity, batch-to-batch stability and absence of contamination are the keys to the success of organoid experiments. This recombinant human Noggin is supplied in liquid form with high activity, no animal-derived components and low endotoxin.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eSpecification \u003c\/strong\u003e\u003c\/h3\u003e\n\u003ctable border=\"0\" cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"200\" valign=\"center\"\u003e\n\u003cp\u003eSynonyms\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"441\" valign=\"center\"\u003e\n\u003cp\u003eNOG, SYM1, symphalangism 1 (proximal), synostoses (multiple) syndrome 1, SYNS1\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"200\" valign=\"center\"\u003e\n\u003cp\u003eSource\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"441\" valign=\"center\"\u003e\n\u003cp\u003eHEK293\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"200\" valign=\"center\"\u003e\n\u003cp\u003eSequence\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"441\" valign=\"center\"\u003e\n\u003cp\u003eGln28-Cys232\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"200\" valign=\"center\"\u003e\n\u003cp\u003eAccession\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"441\" valign=\"center\"\u003e\n\u003cp\u003eQ13253\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"200\" valign=\"center\"\u003e\n\u003cp\u003eMolecular Weight\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"441\" valign=\"center\"\u003e\n\u003cp\u003ePredicted Moleucular weight: 23.1 kDa(Monomer)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"200\" valign=\"center\"\u003e\n\u003cp\u003eEndotoxin\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"441\" valign=\"center\"\u003e\n\u003cp\u003e\u0026lt; 0.01 EU\/μg by the LAL method.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"200\" valign=\"center\"\u003e\n\u003cp\u003ePurity\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"441\" valign=\"center\"\u003e\n\u003cp\u003e\u0026gt; 95%，determined by SDS-PAGE\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"200\" valign=\"center\"\u003e\n\u003cp\u003eBiological Activity\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"441\" valign=\"center\"\u003e\n\u003cp\u003eMeasured by its ability to inhibit BMP4-induced alkaline phosphatase production by MC3T3E1 mouse preosteoblast cells. The EC50 for this effect is 5-40 ng\/mL.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"200\" valign=\"center\"\u003e\n\u003cp\u003eFormulation\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"441\" valign=\"center\"\u003e\n\u003cp\u003eDissolved in sterile PBS buffer.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"200\" valign=\"center\"\u003e\n\u003cp\u003eTag\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"441\" valign=\"center\"\u003e\n\u003cp\u003eNot\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"200\" valign=\"center\"\u003e\n\u003cp\u003ePhysical Appearance\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"441\" valign=\"center\"\u003e\n\u003cp\u003eLiquid\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003e\u003cstrong\u003eStorage \u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e-85~-65℃ storage, valid for 1 year after receipt.\u003c\/p\u003e\n\u003cp\u003eAvoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eFigure\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/2_27cf2122-7428-468a-b32d-631a6fc7cd6e_1024x1024.png?v=1764210470\" alt=\"Figure 1.Measured by its ability to inhibit BMP4-induced alkaline phosphatase production by MC3T3E1 mouse preosteoblast cells. \u0026amp;nbsp;The EC50 for this effect is 5-40 ng\/mL.\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003cp style=\"text-align: center;\"\u003eFigure 1.Measured by its ability to inhibit BMP4-induced alkaline phosphatase production by MC3T3E1 mouse preosteoblast cells.  The EC50 for this effect is 5-40 ng\/mL.\u003c\/p\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/3_34fb3283-17c7-4a15-85b6-e74054dd0edf_1024x1024.png?v=1764210470\" alt=\"Figure 2.Human Noggin Protein on SDS-PAGE under reduced (R) and Non-reducing (NR) conditions. The purity is greater than 95%.\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003cp style=\"text-align: center;\"\u003eFigure 2.Human Noggin Protein on SDS-PAGE under reduced (R) and Non-reducing (NR) conditions. The purity is greater than 95%.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eCautions\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e1. For your safety and health, please wear lab coat and disposable gloves.\u003c\/p\u003e\n\u003cp\u003e2. This product is for scientific research purposes only.\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Yeasen","offers":[{"title":"10 ug","offer_id":51559916962110,"sku":"92623ES10","price":80.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":51559916994878,"sku":"92623ES50","price":245.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":51559917027646,"sku":"92623ES60","price":365.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":51559917060414,"sku":"92623ES76","price":990.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":51386387431742,"sku":"92623ES80","price":1585.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/92623_32c3c3ea-9c66-4bb0-b8ad-cccf2ca4d601.jpg?v=1777444682"}],"url":"https:\/\/www.yeasenbio.com\/collections\/organoid-related-cytokines.oembed","provider":"Yeasen - Leading Innovation in Molecular Enzymes and Reagents","version":"1.0","type":"link"}