{"product_id":"10694","title":"GTP Tris Solution GMP-grade (200 mM) _ 10694ES","description":"\u003cdiv class=\"top_tabc proDetail\"\u003e\n\u003cdiv\u003e\n\u003cdiv\u003e\n\u003cp\u003e\u003cspan\u003eGTP, Guanosine-5'-triphosphate, can be used in various of molecular biology applications, such as in vitro transcription, RNA amplification, siRNA synthesis, etc. In addition, GTP plays an important role in signal transduction as a phosphate or pyrophosphate messenger: GTP can activate G proteins, which can induce multiple protein kinase mediated cascade reactions, causing a variety of cytological behaviors, such as cell proliferation, differentiation, etc. GTP can also be used as a high-energy precursor of single nucleotides to participate in the synthesis of DNase and RNase.\u003cbr\u003eThis product is a transparent colorless aqueous solution prepared with GTP tris solution, and free of DNase and RNase contamination.\u003cbr\u003eThis product is produced in accordance with GMP process requirements and provided in liquid form.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003e\u003cstrong\u003eFeature\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eValidated, product-specific processes and analytical methods\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eProduct-specific stability\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDocumentation follows applicable GMP guidelines\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAOF production process and raw materials (TSE \u0026amp; BSE) \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eNitrosamine statement\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eRegulatory support documents available\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eLarge-scale production\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eThe increased IVT yield and the decreased dsRNA content under the optimized Tris NTP reaction system\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003e\u003cstrong\u003eApplication\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eRNA synthesis and amplification\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eBuilding block for in vitro transcription\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 class=\"H3_backgro\"\u003e\u003cstrong\u003e\u003cspan\u003eSpecification\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eCAS No\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e86-01-1 (free acid)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eFormula\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eC\u003csub\u003e10\u003c\/sub\u003eH\u003csub\u003e16\u003c\/sub\u003eN\u003csub\u003e5\u003c\/sub\u003eO\u003csub\u003e14\u003c\/sub\u003eP\u003csub\u003e3\u003c\/sub\u003e (free acid)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eMolecular weight\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e523.18 g\/moL (free acid)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003ePurity(HPLC)\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e≥ 99%\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eContent\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e200 mM ± 3 mM\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eStructure\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e\u003cimg src=\"https:\/\/seas.ysbuy.com\/file\/54747\/46f2-166433967152171669.png\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"H3_backgro\"\u003e\u003cstrong\u003e\u003cspan\u003eComponent\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cdiv class=\"tableResponsive\"\u003e\n\u003ctable cellspacing=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eComponents No.\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eName\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e10694ES03\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e10694ES10\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e10694ES60\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e10694\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eGTP Tris Solution GMP-grade (200 mM)\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e1 mL\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e10 mL\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e100 mL\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"H3_backgro\"\u003e\u003cstrong\u003e\u003cspan\u003eStorage\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eThe product should be stored at -25℃ ~ -15℃ for two years.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 class=\"H3_backgro\"\u003e\u003cstrong\u003e\u003cspan\u003eFigures\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eIncreased the IVT yield\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003e\u003cimg style=\"display: block; margin-left: auto; margin-right: auto;\" src=\"https:\/\/seas.ysbuy.com\/file\/252672\/39cd-167539382289035951.png\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: center;\"\u003e\u003cspan\u003e\u003cstrong\u003eFigure 1. The IVT yield was significantly increased under the optimized Tris NTP reaction system, compared with the sodium NTP reaction system.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eDecreased the dsRNA content\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003e\u003cimg style=\"display: block; margin-left: auto; margin-right: auto;\" src=\"https:\/\/seas.ysbuy.com\/file\/189799\/30e1-167539384755655451.png\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: center;\"\u003e\u003cspan\u003e\u003cstrong\u003eFigure 2. The content of dsRNA was significantly decreased under the optimized Tris NTP reaction system, compared with the sodium NTP reaction system. The content of dsRNA was detected by the Dot Blot method.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"top_tabc\"\u003eDocuments:\u003c\/h3\u003e\n\u003cdiv class=\"top_tabc\"\u003e\n\u003cdiv\u003e\n\u003cdiv class=\"cwrap\"\u003e\n\u003cdiv\u003e\n\u003cdiv class=\"list\"\u003e\n\u003cdiv\u003e\n\u003cdiv\u003e\u003ca class=\"down\" title=\"download\" download=\"\" href=\"https:\/\/seas.ysbuy.com\/prod\/doc\/mainDoc\/10655_Manual_HB230112_EN.pdf\" target=\"_blank\"\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Yeasen","offers":[{"title":"1 mL","offer_id":54337114997054,"sku":"10694ES03","price":320.0,"currency_code":"USD","in_stock":true},{"title":"10 mL","offer_id":54337115029822,"sku":"10694ES10","price":2560.0,"currency_code":"USD","in_stock":true},{"title":"100 mL","offer_id":54337115062590,"sku":"10694ES60","price":18920.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0803\/9419\/1166\/files\/FoQ39c7By_wC758xUu2RaQKPPEzH.png?v=1768374656","url":"https:\/\/www.yeasenbio.com\/ar\/products\/10694","provider":"Yeasen - Leading Innovation in Molecular Enzymes and Reagents","version":"1.0","type":"link"}